Winter flounder

Flounder, winter (Pseudopleuronectes americanus) Winter, spring 500,000-1,500,000... 

Calabrese A, Thurberg FP, Dawson MA, WenzlofF DR. 1975. Sublethal physiological stress induced by cadmium and mercury in the winter flounder (Pseudoplumnectes amer-icanus). In Koeman JH, Strik JJ, editors, Sublethal effects of toxic chemicals on aquatic animals. Amsterdam Elsevier. 

Winter flounder, Pleuronectes americanus 5.0 60 days Increased gill tissue respiration 18... 

Calabrese, A., F.R Thurberg, M.A. Dawson, and D.R. Wenzloff. 1975. Sublethal physiological stress induced by cadmium and mercury in winter flounder, Pseudopleuronectes americanus. Pages 15-21 in J.H. Koeman and J.J.T.W.A. Strik (eds.). Sublethal Effects of Toxic Chemicals on Aquatic Animals, Elsevier Sci. Publ. Co., Amsterdam. 

Jessen-Eller, K. and J.F. Crivello. 1998. Changes in metallothionein mRNA and protein after sublethal exposure to arsenite and cadmium chloride in juvenile winter flounder. Environ. Toxicol. Chem. 17 891-896. 

Winter flounder, Pleuronectes americanus New York Muscle Liver Texas Muscle Skin... 

Baker, J.T.P. 1969. Histological and electron microscopical observations on copper poisoning in the winter flounder (Pseudopleuronectes americanus). Jour. Fish. Res. Bd. Can. 26 2785-2793. 

February-March 1989 muscle Winter flounder, Pleuronectes americanus ... 

Klein-MacPhee, G., J.A. Cardin, and WJ. Berry. 1984. Effects of silver on eggs and larvae of the winter flounder. Trans. Amer. Fish. Soc. 113 247-251. 

Johnson, L.L., C.M. Stehr, O.P. Olson, M.S. Myers, S.M. Pierce, C.A. Wigren, B.B. McCain, and U. Varanasi. 1993. Chemical contaminants and hepatic lesions in winter flounder (Pleuronectes americanus) from the northeast coast of the United States. Environ. Sci. Technol. 27 2759-2771. 

Elskus, A.A., J J. Stegeman, J.W. Gooch, D.E. Black, and R.J. Pruell. 1994. Polychlorinated biphenyl congener distributions in winter flounder as related to gender, spawning site, and congener metabolism. Environ. Sci. Technol. 28 401-407. 

Greig, R.A. and G. Sennefelder. 1987. PCB concentrations in winter flounder from Long Island Sound, 1984—1986. Bull. Environ. Contam. Toxicol. 39 863-868. 

McElroy, A.E., J.M. Cahill, J.D. Sisson, and K.M. Kleinow. 1991. Relative bioavailability and DNA adduct formation of benzo[a]pyrene and metabolites in the diet of the winter flounder. Comp. Biochem. Physiol. 100C 29-32. 

McEboy, A.E. and RD. Colarusso. 1988. Disposition of dietary benzo[a]pyrene in aquatic species winter flounder (Pseudopleuronectes americanus) and green crab (Carcinus maenas). Bull. Mt. Desert Isl. Biol. Lab. 27 45-57. 

Payne, J.F., J. Kiceniuk, L.L. Fancey, U. Williams, G.L. Fletcher, A. Rahimtula, and B. Fowler. 1988. What is a safe level of polycyclic aromatic hydrocarbons for fish subchronic toxicity study on winter flounder (Pseudopleuronectes americanus). Canad. Jour. Fish. Aquat. Sci. 45 1983-1993. 

As 3 Winter flounder, Pteuronectes americanus 7.2 LC100 (7 days) 3... 

The winter flounder antifreeze protein (AFP), characterized by Sicheri and Yang [42], consists of 37 residues of eight amino acids in an a-helix configuration. The AFP protein was synthesized by the conjoining of the Aa residues determined in the glycine mold, with the exception of the two residues at each of the termini, FIOOC-Asp Thr and Ala Arg-NP and the synthesized protein fragment is left with open amidic surfaces on the... 

Fig. 7.6 The 33-residue fragment of the winter flounder antifreeze protein (AFP), constructed by the conjoining of the Aa amino acid residues defined within the glycine mold , pictured in terms of its 0.001 au isodensity envelope, its van der Waals envelope. This is a view showing the ice-binding motif. It is believed that the AFP strand binds... 

Canada [8]. In this document all three approaches have been performed after an extensive literature study of effects documented and environmental concentrations measured in the Canadian aquatic environment. Thus, based on the most sensitive endpoint found in the literature (LC50 of nonylphenol (NP) for winter flounder 17 pig L-1 [9]), and applying an uncertainty factor of 100, for NP a PNEC of 0.17 p.g L-1 was derived. Analogously, NEC were derived for nonylphenol ethoxylates (NPEO) and nonylphenol ethoxy carboxylates (NPEC) these are listed in Table 7.4.1. 

In this report we compare several properties of hepatic microsomal AHH activity in control and DBA-treated little skates (including metabolic profiles obtained from c-benzo(a)pyrene as elucidated by high pressure liquid chromatography [HPLC]), we describe the partial purification of two different forms of cytochrome P-450 (cytochrome P-448 and cytochrome P-451) from hepatic microsomes of DBA-pretreated little skates and we report polycyclic hydrocarbon-like induction in large numbers of winter flounder assayed in Maine during June, July, and August, which was quite different than data obtained with sheepshead examined in Florida during the same period. 

In spite of these limitations there seems little doubt that induction of the hepatic MFO system in certain fish can indicate the presence of selected toxic chemicals (to fish and humans) in both freshwater and marine environments. For this reason we have been studying various aspects of this question for the last few years in freshly captured fish (winter flounder and little skate in Maine and the sheepshead in Florida) and in fish induced by polycyclic hydrocarbon administration. 

One of our more interesting observations is illustrated in Table III. The administration of DBA to winter flounder increased hepatic microsomal AHH and 7-ethoxyresorufin deethylase activities as expected, and AHH activity was strongly inhibited in the DBA-treated flounder by 10" M a-naphthoflavone as we have previously reported for both little skate (4) and sheepshead (9). However, the presence of high AHH and 7-ethoxyresorufin deethylase activities in one control flounder, and the inhibition of AHH activity by a-naphthoflavone in this animal suggested that the hepatic microsomal MFO system of this fish was already induced. 

EFFECT OF 1,2,3,4-DIBENZANTHRACENE (DBA)-PRETREATMENT ON HEPATIC MICROSOMAL 3ENZ0(a)PYRENE HYDROXYLASE (AHH) AND 7-ETH0XYRES0RUFIN DEETHYLASE (7-ERF) ACTIVITIES IN WINTER FLOUNDER... 

Bend, J. R., Bogar, A., and Foureman, G. L. Partially induced hepatic microsomal mixed-function oxidase systems in individual winter flounder, Pseudoplenroneates ameriaanus, from coastal Maine. Bull. Mt. Desert Island Biol. Lab. (1977) 17 47-49. 

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