Ethoxyresorufin-O-deethylase activity

Kannan, K., D.L. Villeneuve, A.L. Blankenship, and J.P. Giesy. 1998b. Interaction of tributyltin with 3,3, 4,4, 5-pentachlorobiphenyl-induced ethoxyresorufin O-deethylase activity in rat hepatoma cells. Jour. Toxicol. Environ. Health 55A 373-384. 

Single ip injection of 30 mg PCB 118/kg BW to immatures. Fish killed 4 days later and liver analyzed Liver EROD (7-ethoxyresorufin O-deethylase) activity was 5.6 times higher than controls AHH activity was 2.7 times higher than controls 5... 

M (cytoplasmic vacuolation, accentuation of zonation, increased ethoxyresorufin-O-deethylase activity) 402.9 F (cytoplasmic vacuolation, accentuation of zonation, increased ethoxyresorufin-O-deethylase activity)... 

Golor G, Neubert D. 1989. EROD (ethoxyresorufin-o-deethylase) activity in rat liver tissue after application of TCDD and OCDD alone and in combination [Abstract]. Naunyn Schmiedeberg s Arch Pharmacol 339 10. 

Schulz-Schlage T, Golor G, Stahlmann R. 1992. Biological effect of high doses of TCDD in the marmoset monkey, Callithrixjacchus, Plateau of ethoxyresorufin O-deethylase activity in liver microsomes. Chemosphere 25(7-10) 991-995. 

Weber LW, Lebofsky M, Stahl BU, et al. 1992b. Comparative toxicity of four chlorinated dibenzo-p-dioxins (CDDs) and their mixture. Part III Structure-activity relationship with increased plasma tryptophan levels, but no relationship to hepatic ethoxyresorufin o-deethylase activity. Arch Toxicol 66(7) 484-488. 

Bols, N.C., K. Schirmer, E.M. Joyce, D.G. Dixon, B.M. Greenberg and J.J. Whyte. Ability of polycyclic aromatic hydrocarbons to induce 7-ethoxyresorufin-o-deethylase activity in a trout liver cell line. 

Schirmer, K., D.J. Tom, N.C. Bols and J.P. Sherry. Ability of fractionated petroleum refinery effluent to elicit cyto- and photocytotoxic responses and to induce 7-ethoxyresorufin-o-deethylase activity in fish cell lines. Sci. Total Environ. 271 61-78, 2001. 

Tom, D.J., L.E.J. Lee, J. Lew and N.C. Bols. Induction of 7-ethoxyresorufin-o-deethylase activity by planar chlorinated hydrocarbons and polycyclic aromatic hydrocarbons in cell lines from the rainbow trout pituitary. Comp. Biochem. Physiol. 128A 185-198, 2001. 

Nacci, D., L. Coiro, A. Kuhn, D. Champlin, W. Munns, J. Specker and K. Cooper. Nondestructive indicator of ethoxyresorufin-O-deethylase activity in embryonic fish. Environ. Toxicol. Chem. 17 2481—2486,1998. 

Huang Y-W, Karasov WH, Patnode KA, et al. 1999. Exposure of northern leopard frogs in the Green Bay ecosystem to polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins, and polychlorinated dibenzofurans is measured by direct chemistry but not hepatic ethoxyresorufin-O-deethylase activity. Environ Toxicol Chem 18(10) 2123-2130. 

Achazi. R. K., Chroscz, G.. Heimig. E.. Neunaber. R., and Steudel, 1. (1994). A high molecular regulator of 7-ethoxyresorufin-o-deethylase activity in fish. Comp. Biodiem. Physiol. C 108, 243-256. 

Table 5 Chlorinated polycyclic aromatic hydrocarbons (CIPAH) activity expressed as (a) EROD (ethoxyresorufin-O-deethylase) activity as the relative intensity of ClPAH-mduced cytochrome P450 (CYP) activity in human breast cancer MCF-7 cells [228] (b) environmental fate [Bioaccumulation aquatic] in Pimephales promelas over 96 h [10 L/kg wet] (c) ecotoxicological information [Aquatic Toxicity] LC50 for Pimephales promelas after 96 h [10 mg/L] and (d) carcinogenity in rats, TD50 [10 mol/kg]...

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