Flavonoids thyme

Negative atmospheric pressure chemical ionization (APC) low-energy collision activation mss spectrometry has also been employed for the characterization of flavonoids in extracts of fresh herbs. Besides the separation, quantitative determination and identification of flavonoids, the objective of the study was the comparison of the efficacy of the various detection systems in the analysis of flavonoids in herb extracts. Freeze-dried herbs (0.5g of chives, cress, dill, lovage, mint, oregano, parsley, rosemary, tarragon and thyme) were ground and extracted with 20 ml of 62.5 per cent aqueous methanol. After sedimentation the suspension was filtered and used for HPLC analyses. Separations were carried out in an... 

Spices (rosemary, sage, thyme) contain considerable amounts of flavonols and flavones, mainly in the glycoside form (154). Thus, phenolic analyses in spices were often considered in order to determine the optimum time for plant collection to give maximum flavonoid contents and for health benefits (154,155). Flavonoids (naringin, luteolin, apigenin, and chrysoeriol) were extracted from spices using a percolation process at room temperature with solvents (MeOH and EtOAc), and HPLC analysis was carried out (155). 

The flavonoids are a group of secondary metabolites widely distributed in the plant kingdom [63]. In 1984, more than 4000 flavonoids were identified in plants [64]. The major dietary sources of flavones are spices and pot herbs, such as parsley, rosemary, and thyme [65], whereas flavonols are predominantly found in onions, kale, broccoli, apples, berries and cherries, and in tea and red wine [66]. The flavanones are mainly restricted to citrus fruits [67], and flavanols are found in considerable amounts in tea, apricots, apples, and cherries [66]. 

Labiatae Basil, marjoram, mint, thyme, rosemary, dill, oregano, sage Mono-, diterpenes, flavonoids, rosmarol, ursolic acid, phenolic derivatives... 

Extracts derived from most members of the Labiatae family (Table 3) have the potential to reduce the oxidation of food products and extend shelf life. This antioxidant action is dependent on the ability of the constituent phenolics to scavenge free radicals and chelate metals [27]. This dual effect has implications for CHD since it has been proposed in some studies, mainly from Europe, that a high status of iron increases the risk of CHD [28]. A number of the active compounds found in rosemary have also been found in sage and other herbs. In oregano, four flavonoids were identified among the active fraction [29], while in thyme, dimers of thymol and flavonoids have been isolated and characterized. 

As shown by recent studies, a number of natural extracts from selected herbs (such as rosemary, sage, oregano, and thyme), which were found to be rich in polyphenols, flavonoids, and other compounds, have been well proved to be effective in retarding the development of rancidity in oils and fatty acids. Indeed, the activity of the natural extracts has been found to be dependent, among other factors, on the type and polarity of the extraction solvent, the isolation procedures, and the active components from the raw materials."" ... 

Thyme is rich in antioxidant molecules which include phenolic compounds, flavonoids, essential oils, tannins, and catechins [28,90]. Some of the most predominant phytochemicals in thyme include ter-pineol, anethole, apigenin, rosmarinic acid, myristic acid, palmitic acid, kaempferol, ferulic acid, caffeic acid, thymol, anethol, carvacrol, euge-nol [28,90]. Thyme has traditionally been used as a natural remedy for a variety of applications including as an antibacterial and antitussive... 

LUT belongs to the sub-class of flavonoids known as flavones, and is one of the most bio-active flavonoids. It is found mainly in parsley, thyme, and peanut hull. Possesses in its molecular structure two benzene rings linked through a heteroc cle. One of the benzene ring has two hydroxyls in the meta position (resorcinol) and the other ring has two hydroxyls in ortho position (catechol). LUT is important since several beneficial effects on human health have been reported, such as cardiovascular protection, anticancer activity, anti-allergic activity and the prevention of cataracts (Lopez-Lazaro, 2009). 

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