Fibrous meshes

The DNA-containing nucleus has been described as a balloon filled with thick solution with a fibrous mesh which holds the DNA in place and which moves molecules about. 

Different photocatalytic reactor configurations are reported in the literature including annular reactor with a small thin film of catalyst coated on the iimer surface of the outer annulus, flat-plate fluidized beds, annular packed beds, and catalyst coated on honeycombed monoliths, porous fibrous mesh, and optical fiber bundles (31,32). 

On secretion from the cell, the tropoelastin is aligned with the microfibrils, and lysyl oxidase initiates the reactions that cross-link elastin molecules, using lysine residues within the hydrophilic alternating domains in the proteins. This cross-linking reaction is the same as that which occurs in collagen. In this reaction, 2, 3, or 4 lysine residues are cross- linked to form a stable stracture. The net result of the cross-linking is the generation of a fibrous mesh that encircles the cells. 

Supported Ti02 on porous fibrous meshes (Ibrahim and de Lasa, 2002 Feral and Ollis, 1992), on monoliths (Blanco et al., 1996b), on honeycombs (Suzuki, 1993)... 

The behavior of stem cells in a 3D environment is well worth studying, since most practical applications of tissue repair and regeneration are accomplished by materials with a 3D structure, such as scaffolds, hydrogels, fibrous meshes, and microspheres. 

To investigate their biocompatibifity with woimded tissue, SELP-7 and SELP-5 fibrous meshes were appfied to porcine dermal wounds. No adverse effects were observed and the wounds (2x2 cm partial and fiill dermal thickness) were completely epithelialized after 14 days. Histological evaluation revealed that some SELF filaments had been incorporated into the healing tissue. Similar results were observed with SELF sponges (2). 

Focus has changed with time from nonabsorbable to absorbable polymers. Absorbable polymers typically take the form of fibrous meshes, porous scaffolds, or hydrogels. If the polymer can degrade at a controlled rate, the body s own cells can infiltrate the matrix and replace the polymer space with natural tissue. The use of an absorbable polymer can have many advantages, such as the following ... 

Selection of a tissue engineering substrate includes a choice between absorbable and nonabsorbable material, as well as a choice between synthetic and naturally derived materials. The most common synthetic polymers used for fibrous meshes and porous scaffolds include polyesters such as polylactide and polyglycolide and their copolymers, polycaprolactone, and polyethylene glycol. Synthetic polymers have advantages over natural polymers in select instances, such as the following i... 

In a similar study, osteoblasts, osteocytes, and chondrocytes were grown on fibers obtained from a nonwoven mesh of polyglycolide. Vacanti and coworkers demonstrated that polyglycolide can be used as a matrix for bone and cartilage cell transplantation. A drawback to the use of these fibrous meshes was their insufficient compressive properties. In a study by Mooney... 

Bone is a natural composite comprised of type I collagen and calcium phosphate minerals, of which nanocrystalline apatite is the main component [39, 40]. Certain osteoconductive bioceramics exert an effect on bone cell attachment and growth factor binding or release, and can accelerate the treatment of bone defects [41-43]. Polymer composite scaffolds can be produced, via electrospinning, which contain a specific amount of electrical charge in order to form non-woven fibrous meshes with fibre dimensions in the nano- to microscale [44-46]. 

B) SEM image of PCL/PEI electrospun nanofibers (C) absence of red fluorescence in PCL fibrous meshes stained with Texas Red avidin (D) red fluorescence in PCL/PEI fibrous meshes stained with Texas Red avidin (E) fluorescent image of electrospun PCL meshes pretreated with DNA and stained with fluorescent-tagged Hoechst 33258 (F) fluorescent image of electrospun PCL/PEI meshes pretreated with DNA and stained with fluorescent-tagged Hoechst 33258. 

Dinucci, D., and Chiellini, F. (2010) Poly(lactic-co-glycolic acid) electrospun fibrous meshes for the controlled release of retinoic acid. Acta Biomater.,... 

Orientation In the particular case of nerve guide substitutes engineering, orientation of fibers rightly scaled in a parallel distribution have shown to guide axon extension and Schwann cell growth by contact guidance on the surface without infiltration into the inner network while random fibrous mesh are infiltrated. 

SELF polymers were fabricated as nonwoven fibrous meshes to produce fibrillar mats which were flexible, had good drapability, and were stable in wet environments. Fibrous meshes were produced from SELP5, SELF , and SELFF by extruding the polymer dope containing 20-33% (w/v) protein into a high velocity gas stream. 

Fine filaments were collected on a circular, metal wire loop forming a web of suspended filaments in the center. Webs were removed from the loop and pressed into fibrous meshes. The meshes were stabilized by immersing them in either methanol or ethanol and dried under ambient conditions. The meshes were sterilized by electron beam irradiation at a dose of 2.5 MRads. 

Shin, M., Ishii, O., Sneda, T, Vacant , J.R, 2004. Contractile cardiac grafts using a novel nano-fibrous mesh. Biomaterials 25, 3717-3723. 

Three-dimensional porous scaffolds have been developed in several forms (eg, fibrous meshes, foams, sponge-Uke structures, hydrogels, microparticles, selfassembling peptides) by means of a wide range of fabrication techniques such as... 

Dermagraft Organogenesis Inc. (US) Poly(glycolic acid) fibrous mesh cultured with human fibroblasts Healing of chronic diabetic foot ulcers Marketed... 

Shin, Y. M., Shin, H., and Lim, Y. M. 2010. Siuface modification of electrospun poly(L-lactide-co-e-caprolactone) fibrous meshes with a rgd peptide for the control of adhesion, proliferation and differentiation of the preosteoblastic cells. Macromol Res 18 472-81. 

Wan, Y., et al. (2008). Preparation and mechanieal properties of poly(chitosan-g-DL-lactic acid) fibrous mesh scaffolds. Polymers for Advanced Technologies, 19(2), 114-123. 

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