Transplantation cartilage cell

In a similar study, osteoblasts, osteocytes, and chondrocytes were grown on fibers obtained from a nonwoven mesh of polyglycolide. Vacanti and coworkers demonstrated that polyglycolide can be used as a matrix for bone and cartilage cell transplantation. A drawback to the use of these fibrous meshes was their insufficient compressive properties. In a study by Mooney... 

Risbud M., Ringe J., Bhonde R., Sittinger M., In vitro expression of cartilage-specific markers by chondrocytes on a tno-compatible hydrogel Implications for engineering cartilage tissue. Cell Transplant., 10,2001,155-763. 

Kim W S, Vacanti J P, Cima L et al., Cartilage engineered in predetermined shapes employing cell transplantation on synthetic biodegradable polymers , Plast. Reconstr. Surg., 1994, 94, 233-7. 

Zhu, S., Zhang, B., Man, C., Ma, Y., Liu, X., Hu, J., 2014. Combined effects of connective tissue growth factor-modified bone marrow-derived mesenchymal stem cells and NaOH-treated PLGA scaffolds on the repair of articular cartilage defect in rabbits. Cell Transplantation 23, 715-727. 

H., 2011. Safety of autologous bone marrow-derived mesenchymal stem cell transplantation for cartilage repair in 41 patients with 45 joints followed for up to 11 years and 5 months. Journal of Tissue Engineering and Regenerative Medicine 5, 146-150. 

In practical veterinary the SC can be used in substitution therapy in case of different pathologies. The methods of making 3-D cell construction have been already invented and are applied for the substitution of large bone, skin, and cartilage defects. The transplantation of bone marrow stem cells is used in the case of animal oncology diseases. The methods of cell therapy with the usage of SC are approbated in the treatment of autoimmune and endocrine diseases of domestic animals. 

Human cells, tissues, or organs implanted or transplanted in animals present a relatively strong and valuable tool, provided that immune rejection of the human material can be avoided. Immune-deficient animals like mice may well be used to develop organ-like structures (teratomas) from transplanted stem cells [13] or with combinations of human cells or human tissue (e.g., synoviocytes and cartilage [14], and activated mononuclear cells and transplanted skin [15]). 

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