Mass spectrometry fatty acids

N. J. Jensen and M. L. Gross, Mass spectrometry methods for structural determination and analysis of fatty acids. Mass Spectmm. Rev. 6, 497-536 (1987). 

Oils are mixtures of mixed esters with different fatty acids distributed among the ester molecules. Generally, identification of specific esters is not attempted instead the oils are characterized by analysis of the fatty acid composition (8,9). The principal methods have been gas—Hquid and high performance Hquid chromatographic separation of the methyl esters of the fatty acids obtained by transesterification of the oils. Mass spectrometry and nmr are used to identify the individual esters. It has been reported that the free fatty acids obtained by hydrolysis can be separated with equal accuracy by high performance Hquid chromatography (10). A review of the identification and deterrnination of the various mixed triglycerides is available (11). 

A. Fox. R. M. T. Rosario, and L. Larsson, Monitoring of bacterial sugars and hydroxy fatty acids in dust from air conditions by gas chromatography-mass spectrometry. Appl. Environ. Microbiol.. 59 4354 (1993). 

Suzuki, K. Application of mass spectrometry to bacterial taxonomy. Cellular fatty acids and isoprenoid quinones. Iyo Masu Kenkyukai Koenshu 1987,12,45-53. 

DeLuca, S. Sarver, E. W. Harrington, P. d. B. Voorhees, K. J. Direct analysis of bacterial fatty acids by Curie-point pyrolysis tandem mass spectrometry. Anal. Chem. 1990, 62,1465-1472. 

Basile, F. Voorhees, K. J. I Iadfield.T. L. Microorganism Gram-type differentiation based on pyrolysis mass-spectrometry of bacterial fatty-acid methyl-ester extracts. Appl. Environ. Microbiol. 1995, 61,1534-1539. 

Beverly, M. B. Basile, F. Voorhees, K. J. Fatty acid analysis of beer spoiling microorganisms using pyrolysis mass spectrometry. J. Am. Soc. Brewing Chemists 1997, 55,79-82. 

Gharaibeh, A. A. Voorhess, K. J. Characterization of lipid fatty acids in whole-cell microorganisms using in situ supercritical fluid derivatization/extraction and gas chromatography/mass spectrometry. Anal. Chem. 1996,68,2805-2810. 

W.J. Muizebelt, M.W.F. Nielen, Oxidative crosslinking of unsaturated fatty acids studied with mass spectrometry, Journal of Mass Spectrometry, 31, 545 554 (1996). 

J.M. Challinor, A rapid simple pyrolysis derivatisation gas chromatography mass spectrometry method for profiling of fatty acids in trace quantities of lipids, J. Anal. Appl. Pyrol., 37,185 197 (1996). 

Organic Mass Spectrometry in Art and Archaeology 14.9.7 The Hydrogen Isotopic Composition of Fatty Acids... 

Metges, C. C., Kempe, K. and Wolfram, G. (1994) Enrichment of selected serum fatty acids after a small oral dosage of (1 C 13)triolein and (8 C 13)triolein in human volunteers analyzed hy gas chromatography combustion isotope ratio mass spectrometry. Biological Mass Spectrometry 23,295 301. 

Scrimgeour, C. M., Begley, I. S. and Thomason, M. L. (1999) Measurement of deuterium incorporation into fatty acids by gas chromatography/isotope ratio mass spectrometry. Rapid Communications in Mass Spectrometry 13, 271. 

Takaichi S, Matsui K, Nakamura M, Muramatsu M and Hanada S. 2003. Fatty acids of astaxanthin esters in krill determined by mild mass spectrometry. Comp Biochem Physiol 136(2) 317-322. 

W.J. Griffiths, Tandem mass spectrometry in the study of fatty acids, bile acids, and steroids, Mass Spectrom. Rev., 22 (2003) 81-152. 

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