Fast liquid chromatography, for

Zhang, H., Heinig, K., and Henion, J. (2000). Atmospheric pressure ionization time-of-flight mass spectrometry coupled with fast liquid chromatography for quantitation and accurate mass measurement of five pharmaceutical drugs in human plasma. J. Mass Spectrom. 35 423-431. 

D. V. McCalley, Comparison of conventional microparticulate and a monolithic reversed-phase column for high-efficiency fast liquid chromatography for basic compounds,/. Chromatogr. 965 (2002), 51-64. 

S. R. Perrin, Fast liquid chromatography for the resolution of chiral compounds, Chirality, 3 188 (1991). 

Nunez, O., Gallart-Ayala, H., Martins, C. P. B., and Lucci, P. 2012. New trends in fast liquid chromatography for food and environmental analysis. J. Chromatogr. A. 1228 298-323. 

Jeffrey, B.S.J. (1991) Silver complexation liquid chromatography for fast high-resolution separation of triacyglycerols. J. Am. Oil Chem. Soc., 68(5), 289-293. 

Magiera, S., Baranowska, I. A new and fast strategy based on semiautomatic microextraction by packed sorbent followed by ultra high performance liquid chromatography for the analysis of drugs and their metabolites in human urine. J. Sep. Sci. 37, 3314—3320 (2014)... 

Schafer, C. Lubda, D. Alkyl Diol Silica Restricted Access Pre-Column Packings for Fast Liquid Chromatography-Integrated Sample Preparation of Biological Fluids, J. Chromatogr. A 909,73-78 (2001). 

Hsieh, Y. et al., Comparison of fast liquid chromatography/tandem mass spectrometric methods for simultaneous determination of cladribine and clofarabine in mouse plasma, J. Pharm. Biomed. Anal., 44(2), 492, 2007. 

Wainhaus, S. et al., Ultra fast liquid chromatography-MS/MS for pharmacokinetic and metabolic profiling within drug discovery, Am. Drug Discov., 2(1), 6, 2007. 

Guillarme, D. et al., Method transfer for fast liquid chromatography in pharmaceutical analysis Application to short columns packed with small particle. Part II Gradient experiments, Eur. J. Pharm. Biopharm., 68(2), 430, 2008. 

An alternative strategy for fast liquid chromatography uses short columns packed with small particles operated at high flow rates and often elevated temperatures to separate simple mixtures under conditions were resolution is compromised but still adequate for identification purposes [252-258]. Small diameter particles provide larger plate numbers by virtue of their relatively small interparticle mass transfer resistance combined with a shallow increase in the reduced plate height as the reduced mobile... 

In-process analysis depends very often on fast analysis, no matter on where this occurs - either research or production processes, continuous or batch processes. A reduction in the analysis time always results in a higher information density, which normally translates into an economical benefit downstream. It is an interesting notion the speed potential of modern UHPLC finally enabled the use of liquid chromatography for current in-process analysis, but is yet very rarely found there. 

Mezcua, M., O. Malato, J. F. Garcia-Reyes, A. Molina-Dlaz, and A. R. Femandez-Alba. 2009. Accurate-mass databases for comprehensive screening of pesticide residues in food by fast liquid chromatography time-of-flight mass spectrometry,. dna/. Chem. 81 913-929. 

Huerta-Fontela M, Galceran MT, Ventura F. Fast liquid chromatography—quadrupole-linear ion trap mass spectrometry for the analysis of pharmaceuticals and hormones in water resources. J Chromatogr A 2010 1217(25) 4212—22. 

Lu Y, Shen Q, et al. Development of an on-line matrix solid-phase dispersion/fast liquid chromatography/tandem mass spectrometry system for the rapid and simultaneous determination of 13 sulfonamides in grass carp tissues. J Chromatogr A 2011 1218(7) 929-37. 

Gallart-Ayala H, Moyano E, et al. On-line solid phase extraction fast liquid chromatography-tandem mass spectrometry for the analysis of bisphenol A and its chlorinated derivatives in water samples. J Chromatogr A 2010 1217(21) 3511—8. 

FIGURE 5 Example of MCR applied to qualitative and quantitative analysis of compounds in strawberry samples by means of fast liquid chromatography and MCR-ALS. The multiset is formed by four triplicate standard mixtures of the phenolic acids at different concentration levels. Eight chromatographic runs of pure standard samples were also used for optimal MCR-ALS resolution. Source. Mas et al. [32]. 

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