Experimenters marijuana

Cannabis can also be administered orally, although this route of administration is now rarely used experimentally. Marijuana plant material is crushed into a powder, which then is baked into a brownie or similar easily consumed food (14). 

Loeber RT and Yurgelun-Todd DA (1999). Human neuroimaging of acute and chronic marijuana use Implications for frontocerebellar dysfunction. Human Psychopharmacology Clinical and Experimental, 14, 291-304. 

Robb HWJ and O Hanlon JF (1993). Marijuana s effect on actual driving Summary of a 3-year experimental program. In HD Utzelmann, G Berghaus and G Kroj (eds), Alcohol, Drugs and Traffic Safety (No. T92, pp. 603-611). Verlag TUV, Cologne. 

Because of the pathological elements in this written description, the student was advised by several people to do no more drug experimentation. However, about a year later, the student accepted a friend s invitation to smoke marijuana. The session began with a number of pleasant bodily feelings and unusual perceptual impressions. Suddenly, the student became obsessed with the notion that his friend desired to have sexual relations with him. The student s friend called the police, and the student was rushed to a hospital, having... 

Given the popularity of marijuana, LSD, mescaline, cocaine, and heroin, the use of ketamine in the 1970s and 1980s remained largely confined to either experimental therapeutic use, or what has been described by author Jay Stevens as the neuro-consciousness frontier, a small group of accredited and unaccredited individuals who experimented with the effects of hallucinogenic substances. 

Wenger, T., Croix, D., Tramu, G., and Leonardelli,J. (1992). Marijuana and reproduction. Effects on puberty and gestation in female rats. Experimental results. Ann. Endocrinol. (Paris) 53, 37—43. 

It is the character of Kennedy s friends rather than his own low personal standard of morality that explains why as a leader of the powerful Senate Judiciary Committee he has come forward as the leading sponsor of federal legalization of marijuana and why he has given his approval to decriminalization of heroin "for experimental purposes." The job of the Kennedy dynasty is to usher in British dope and the criminals who distribute it — through the front door. 

When Peter Stafford s Psychedelic Encyclopedia first appeared in 1977, it was a major addition to the literature on an important group of drugs affecting the mind. It provided detailed and straightforward accounts of LSD, mescaline, marijuana, and a host of other chemicals and plants. Stafford s information was accurate, balanced and uncontaminated by polemic. Clearly, he was sympathetic to intelligent experimentation with these agents, and, clearly, he was experienced with them personally, but his purpose was to present a logical selection of facts rather than to push his own views. 

To analyze a urine sample for THC (the chapter-opening molecule), the principal psychoactive component of marijuana, the organic compounds are extracted from urine, purified, concentrated, and injected into the GC-MS. THC appears as a GC peak with a characteristic retention time (for a given set of experimental parameters), and gives a molecular ion at 314, its molecular weight, as shown in Figure 13.6. 

There is now experimental evidence that for high levels of alcohol intoxication there is definite state-specific memory in humans 21. It is an experimental demonstration of the old folk idea that if you lose something while very drunk and cannot find it the next day, you may be able to find it if you get very drunk again and then search. Experiential data collected in my study of marijuana users 105 also indicate the existence of state-specific memory, and I have recently received verbal reports that laboratory studies are finding state-specific memory for marijuana intoxication. There also seems to be state-specific memory for the conditions induced by major psychedelic drugs. 

Altered perception of the passage of time is the second common cognitive effect of cannabis (Chait Pierri, 1992). This is perhaps best described in statements like a few minutes seemed to pass like hours. Phe effect has been noted in both surveys and the experimental literature. However, the time distortion is not as pronounced in the research reports as it is in more subjective self-reports pro ided by marijuana users. 

Abstract Marijuana and other exogenous cannabinoids alter immune function and decrease host resistance to microbial infections in experimental animal models and in vitro. Two modes of action by whichA -tetrahydrocannabinol (THC) and other cannabinoids affect immune responses have been proposed. First, cannabinoids may signal through the cannabinoid receptors CBi and CB2. Second, at sites... 

The studies that have been performed on experimental animals have utilized THC doses in the range of 0.2 to 100 mg/kg. These doses have been administered by different routes to guinea pigs and mice or other rodents. The concentrations of THC measured in the circulation of these animals are achievable in human marijuana smokers following appropriate extrapolation for mass/surface ratio (Rachelefsky and Opelz 1977). 

Ashfaq MK, Watson ES, elSohly HN (1987) The effect of subacute marijuana smoke inhalation on experimentally induced dermonecrosis by S. aureus infection. Immunophar-macol Immunotoxicol 9 319-331... 

Self-administration of d -THC by smoking a marijuana cigarette, where the subject controls the dose and the rate of dosing to achieve a desired effect, might be expected to affect rCBF or rCGM differently from experimenter-controlled i.v. 

Clark LD, Nakashima EN (1968) Experimental studies of marijuana. Am J Psychiatry 125 379-384... 

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