Excess stroke

The most obvious difference is the application of a vertical feed screw which is required to stuff the typically loose, voluminous feed material into the press chamber. Providing predensified material allows to produce briquettes with sufficient size (thickness) without excessive stroke length of the ram. 

The die used for the extrusion of sections is lifted by means of a tube which passes through the container support and is set on a sleeve which is connected to the ejector crosshead. The crosshead is moved up by the two bottom plungers being so designed to form at the same time the cylinders for the two stationary top pullback plungers which are bolted to the frame by two tie-rods each. In order to facilitate dismounting of the sleeves in the dowmward direction, the pistons can perform an excess stroke after the bolts, which hold the sleeve in the crosshead, have first been released. 

A schematic picture of how concentrations might vary across a liquid-vapor interface is given in Fig. III-ll. The convention indicated by superscript 1, that is, the F = 0 is illustrated. The dividing line is drawn so that the two areas shaded in full strokes are equal, and the surface excess of the solvent is thus zero. The area shaded with dashed strokes, which lies to the right of the dividing... 

True. Excessive alcohol use can lead to many health problems. Heart and liver disease, increased risks of strokes, stomach, liver and mouth cancer, and dementia are all associated with excess alcohol use. 

However, when used in excess it can lead to a wide range of physical and mental problems, e.g. heart and liver disease, cancers, increased risk of stroke, mood and personality changes and dementia (Korsakoff s psychosis). 

Kissela B, Schneider A, Kleindorfer D, Khoury J, Miller R, Alwell K, Woo D, Szaflarski J, Gebel J, Moomaw C, PancioU A, Jauch E, Shukla R, Broderick J. Stroke in a biracial population The excess burden of stroke among blacks. Stroke. 2004 35 426 31. 

Finally, AIDS dementia has parallels with cerebral ischemia or stroke and again the key mechanism appears to involve overactivation of glutamate receptors, in particular the NMDA receptor, followed by excessive influx of calcium and the generation of free radicals. 

Rissanen, T.H. et al.. Low serum lycopene concentration is associated with an excess incidence of acute coronary events and stroke the Kuopio Ischaemic Heart Disease Risk Factor Study, Br. J. Nutr., 85, 749, 2001. 

Isolated seizures that are not epilepsy can be caused by stroke, central nervous system trauma, central nervous system infections, metabolic disturbances (e.g., hyponatremia and hypoglycemia), and hypoxia. If these underlying causes of seizures are not corrected, they may lead to the development of recurrent seizures I or epilepsy. Medications can also cause seizures. Some drugs that are commonly associated with seizures include tramadol, bupropion, theophylline, some antidepressants, some antipsy-chotics, amphetamines, cocaine, imipenem, lithium, excessive doses of penicillins or cephalosporins, and sympathomimetics or stimulants. 

Poor sleep architecture and fragmented sleep secondary to OSA can cause excessive daytime sleepiness (EDS) and neu-rocognitive deficits. These sequelae can affect quality of life and work performance and may be linked to occupational and motor vehicle accidents. OSA is also associated with systemic disease such as hypertension, heart failure, and stroke.21-23 OSA is likely an independent risk factor for the development of hypertension.24 Further, when hypertension is present, it is often resistant to antihypertensive therapy. Fatal and non-fatal cardiovascular events are two- to threefold higher in male patients with severe OSA.25 OSA is associated with or aggravates biomarkers for cardiovascular disease, including C-reactive protein and leptin.26,27 Patients with sleep apnea often are obese and maybe predisposed to weight gain. Hence, obesity may further contribute to cardiovascular disease in this patient population. 

Hypertension, or a chronic elevation in blood pressure, is a major risk factor for coronary artery disease congestive heart failure stroke kidney failure and retinopathy. An important cause of hypertension is excessive vascular smooth muscle tone or vasoconstriction. Prazosin, an aradrenergic receptor antagonist, is very effective in management of hypertension. Because oq-receptor stimulation causes vasoconstriction, drugs that block these receptors result in vasodilation and a decrease in blood pressure. 

Hypertension (blood pressure >140/90 mmHg) may be caused by an elevation in cardiac output or excessive vasoconstriction. Diuretics are used in these patients to reduce cardiac output. Assume that the hearts of these individuals are operating on the ascending portion of the cardiac function curve. As the plasma volume is reduced in response to treatment with diuretic drugs, venous return and preload are reduced, as are ventricular filling and stroke volume, and cardiac output, thus bringing blood pressure back within the normal range. 

During IV administration, milrinone increases stroke volume (and cardiac output) with little change in heart rate. It also decreases PAOP by venodilation and thus is particularly useful in patients with a low cardiac index and an elevated LV filling pressure. However, this decrease in preload can be hazardous for patients without excessive filling pressure, leading to a decrease in cardiac index. 

The response-to-injury hypothesis states that risk factors such as oxidized LDL, mechanical injury to the endothelium, excessive homocysteine, immunologic attack, or infection-induced changes in endothelial and intimal function lead to endothelial dysfunction and a series of cellular interactions that culminate in atherosclerosis. The eventual clinical outcomes may include angina, myocardial infarction, arrhythmias, stroke, peripheral arterial disease, abdominal aortic aneurysm, and sudden death. 

Adverse effects include postural hypotension with associated CNS symptoms, reflex tachycardia, headaches and flushing, and occasional nausea. Excessive hypotension may result in MI or stroke. Noncardiovascular adverse effects include rash (especially with transdermal nitroglycerin) and methemoglobinemia with high doses given for extended periods. 

The human body can tolerate only a small range of temperature, especially when the person is engaged in vigorous activity. Heat reactions usually occur when large amounts of water and/or salt are lost through excessive sweating following strenuous exercise. When the body becomes overheated and cannot eliminate this excess heat, heat exhaustion and heat stroke are possible. 

Glutamate that is a major neurotransmitter in the mammalian nervous system not only plays a role in the development of the brain and learning but is also a potent neurotoxin when present in excess at synapses (Plaitakis and Shashidharan, 2000 Rausch et ah, 2006). Glutamate excitotoxicity has been shown to contribute to neuronal degeneration in acute conditions such as stroke, epilepsy, h) oglycemia, and chronic... 

We tested this strategy on the enzyme caspase-3, a cysteine-aspartyl protease that is one of the central executioners of apoptosis. Excess apoptosis is attributed to a variety of diseases, from stroke to Alzheimer s Disease to sepsis, making caspase-3 a popular drug target [25]. The enzyme also made an ideal starting point for constructing extenders. It is well characterized both structurally and mechanistically and contains an active site cysteine residue that is irreversibly alkylated by small molecule inhibitors. 

Enthusiasm is shown by a very long stroke, often in the crossing of the letter "t." If the t-bar is extra long, it means lots of enthusiasm. You ought to notice that the opposite of enthusiasm is a very short t-bar, perhaps on the left side of the stem, and that would be someone who procrastinates. Obviously if you procrastinate excessively you may never get around to achieving your goals. 

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