Examples temporary procedure

Examples of procedural access controls include inventorying keys, changing access codes regularly, and requiring security passes to pass gates and access sensitive areas. In addition, facilities should establish the means to readily identify all employees, including contractors and temporary workers with unescorted access to facilities. 

Figure 2. Insertion/injection experiment process insertion procedure. (A) Manduca Sexto Moth pupa. (B) Implantation of microchip. (C) After insertion. (D) Insertion examples Injection procedure. (E) Prior to injection the insect was stimulated to gauge its baseline activity level. (F) Various chemicals were injected into the thorax to determine the dosage effects on the degree and length of insect temporary paralysis. (G) The moth paralyzes about a minute after injecting 5 pL of LGA. (H) In a successful test, after 2-3 h, the moth recovers sufficiently to flap its wings.

A policy regarding the retention of temporary procedures once they have expired is required. As already noted, the procedures must be removed from the operating manual to minimize the chance of someone using them inadvertently. However, many technicians and managers not unreasonably like to keep copies of the old temporary procedures because they can serve as worked examples, or go-bys, in the event that a similar procedure has to be written at a later date. 

Once a critical instrument loop is identified, a procedure for testing the entire loop must be written. The test procedure will influence the design of the new system, since, if possible, the test should be an actual performance test. For example, if a high temperature should close a valve, the ideal test would consist of raising the temperature to see if the value closes. Efforts should be made to avoid test procedures which require temporary wiring disconnects, valve closures, and so on, which might not be returned properly to operating condition. 

In some cases, further modification of the above-described procedure is required. The synthesis of nakienone B [134] and a similar synthesis of nakienone A [135] have provided such examples (Scheme 1-40). Since any attempts to metallate the dienyl iodide corresponding to the side chain lead to the formation of the corresponding enallene via elimination, the cyclic component must be metallated, necessitating temporary reduction of enones to enols. The high sensitivity of the target molecule requires a non-acidic route. 

If plasma or whole blood is required for analysis, then the blood is collected in a tube containing an anticoagulant. Heparin (sodium salt) is frequently used. However, its effect is temporary and heparin is expensive. Therefore, a more widely used anticoagulant is potassium oxalate, about 1 mg per mL blood. Oxalate precipitates blood calcium, and the calcium is required in the clotting process. Obviously, plasma prepared in this way cannot be analyzed for calcium or potassium many other metals are precipitated by oxalate, and so serum is usually analyzed for these. The usual practice in preparing whole blood or plasma samples is to add the required amount of oxalate in solution form to the collection tube and then to dry the tube in an oven at 110°C. By this procedure, the collected blood is not diluted. For example, 0.5 mL of a 2% potassium oxalate solution would be taken and dried for a 10-mL blood sample. Potassium oxalate causes red cells to shrivel, with the result that the intracellular water diffuses into the plasma. Thus, the plasma should be separated as soon as possible. 

Figure 18.3 shows examples of applying this procedure to benzene-toluene columns with different feed points and different feed compositions. Accordingly, trays 7,10, and 5 or 10 are the best control trays in Fig. 18.3a, b, and c, respectively. Figure 18.4, based on the column in Fig. 18.3a, shows how a variation in control tray temperature affects product composition with a correctly located and an incorrectly located control tray. When the temperature variation is caused by a change of pressure or in the concentration of a nonkey component, it will produce a steady-state offset in product composition. A disturbance in the material or energy balance will cause a similar temperature variation until corrected by the control action in this case, the offset will only be temporary. Figure 18.4 shows that the offset in either case is minimized when the control tray is selected in accordance with Tolliver and McCune s procedure (403). A dynamic analysis by these authors (403) indicated that the control tray thus selected tends to have the fastest, most linear dynamics. 

Related to the above, an employee may take the correct steps to meet the requirements of a regulation, but fail to document the work properly. For example, an employee may develop a temporary operating procedure and discuss it with the operators. However, if it is not written down, it could generate a willful citation. 

It is important to distinguish between temporary operations and rare permanent operations. If an operation is to be carried out just once with no anticipation that it will ever be repeated, then it is temporary. If, however, it is anticipated that the operation will be repeated, then it is rare permanent, and will have its own associated procedures as part of the operating manual. For example, if a vessel is to receive a special chemical treatment say once every 3 years, then that operation is rare permanent. ... 

The above comments do not mean that there is no place for general conclusions and deductions, particularly in reviews as distinct from audits. However, such conclusions should be identified as such. In the above example, the auditor might write, There appears to be no policy for writing operating procedures for temporary operations. This conclusion is based on the following observations... ... 

Protective equipment (e.g., eye protection, temporary barriers, clothing and/or gloves, respirators, etc.) is recommended, for example, only if the hazard analysis indicated a need, or if the Safe Operating Procedure (SOP) requires periods of beam access such as during setup or infrequent maintenance activities. Temporary protective measures for service can be handled in a manner similar to the service of any embedded Class IV laser. 

For example, during maintenance, startups, turnarounds, etc.. It may be desirable to make temporary changes to the BPCS functions. Failures of the administrative procedures may result in the corruption and failure of the SIS. 

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