3- 2- ethylamino

Chemical Name 2-Ethylamino-4-methyl-4-phenyl-6-chloro-4H-3,1 -benzoxazine Common Name —... 

C22H34O3) see Drostanolone 3 -hydroxy-2-ethylamino-acetophenone (C H 3N02 22510-12-9) see Etilefrine... 

Mebeverine (81), a smooth muscle relaxant, is prepared, i. a., by reacting sodium 3,4-dimethoxy-benzoate (77) with 1,4-dichlorobutane to form chloro-ester 78 which is in turn transformed to the corresponding iodide (79) on heating with Nal in methyl-ethyl ketone. Alkylation of 2-ethylamino-3-p-methoxy-phenylpropane (80) with 79 leads to mebeverine... 

Rhena-/3-ketoimine derivatives of several selected 2-ethylamino compounds have been prepared (36). These amines include 2-chloroethyl-amine (a DNA-alkylating reagent), cystamine ( a heparin antagonist), histamine (a potent vasodilator), tryptamine and O-methylserotonin (two indole alkaloids), and 0,0-dimethyldopamine (an adrenergic drug derivative). 

Fig. 57. Tris(2-ethylamino)amine (8) used as central core for the build up of poly-L-lysine cellobioside dendrimers. ... 

In another spectrophotometric procedure Motomizu [224] adds to the sample (2 litres) 40% (w/v) sodium citrate dihydrate solution (10 ml) and a 0.2% solution of 2-ethylamino-5-nitrosophenol in 0.01 M hydrochloric acid (20 ml). After 30 min, add 10% aqueous EDTA (10 ml) and 1,2-dichloroethane (20 ml), mechanically shake the mixture for 10 minutes, separate the organic phase and wash it successively with hydrochloric acid (1 2) (3 x 5 ml), potassium hydroxide (5 ml), and hydrochloric acid (1 2) (5 ml). Filter, and measure the extinction at 462 nm in a 50 mm cell. Determine the reagent blank by adding EDTA solution before the citrate solution. The sample is either set aside for about 1 day before analysis (the organic extract should then be centrifuged), or preferably it is passed through a 0.45 xm membrane-filter. The optimum pH range for samples is 5.5 - 7.5. From 0.07 to 0.12 p,g/l of cobalt was determined there is no interference from species commonly present in seawater. 

N-Ethyl-yV-(6-methyl-2-pyridyl)aminomethylenemalonate (265, R = Me, R1 = R2 = Et) was prepared in 16-66% yields in the reaction of 2-(ethylamino)-6-methylpyridine, diethyl malonate, and ethyl orthoformate in the presence of acidic catalysts (AcOH, EtCOOH, Dianion WK-11) at 150-160°C for 2-3.5 hr [74JAP(K) 109383],... 

Li and Felbeck (1972) reported that the half-lives for atrazine at 25 °C and pH 4 with and without fulvic acid (2%) were 1.73 and 244 d, respectively. The hydrolysis half-lives in a 5 mg/L fulvic acid solution and 25 °C at pH values of 2.9, 4.5, 6.0, and 7.0 were 34.8, 174, 398, and 742 d, respectively. The only product identified was 2-(ethylamino)-4-hydroxy-6-isopropylamino-5-triazine (Khan, 1978). The primary degradative pathway appears to be chemical (i.e., hydrolysis) rather than microbial (Armstrong et al., 1967 Best and Weber, 1974 Gormley and Spalding, 1979 Geller, 1980 Lowder and Weber, 1982 Skipper et al, 1967). 

Chlor-2-( ethylamino-imino-methylamino)-benzimidazol-bis-[Hydrochlorid] 20% Schmp. 192-194° (Zers.)... 

Vi HgtClOJj h5c2-nh2 65° 72 h 20-25° 18 h 2-Ethylamino-I-(3-trifluor-methyl-phenyl)-propan + l-Ethylamino-3- (3-trifluor-methyl-phenyl)-propan 76 17 4... 

VXH OCH, H3° o Li[AlH4]/TKF Q° dann Ruckfl., 12 h N- (2-Ethylamino-2-phen-yl-ethyl) -phenylglycin-methylester 90 1... 

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