Ethyl laurate

Successful results have been obtained (Renfrew and Chaney, 1946) with ethyl formate methyl, ethyl, n-propyl, iso-propyl, n-butyl, iso-butyl, sec.-butyl and iso-amyl acetat ethyleneglycol diacetate ethyl monochloro- and trichloro-acetates methyl, n-propyl, n-octyl and n-dodecyl propionates ethyl butyrate n-butyl and n-amyl valerates ethyl laurate ethyl lactate ethyl acetoacetate diethyl carbonate dimethyl and diethyl oxalates diethyl malonate diethyl adipate di-n-butyl tartrate ethyl phenylacetate methyl and ethyl benzoates methyl and ethyl salicylates diethyl and di-n-butyl phthalates. The method fails for vinyl acetate, ieri.-butyl acetate, n-octadecyl propionate, ethyl and >i-butyl stearate, phenyl, benzyl- and guaicol-acetate, methyl and ethyl cinnamate, diethyl sulphate and ethyl p-aminobenzoate. 

From ethyl laurate by reduction with hydrogen under pressure with copper catalyst. Ger. pat. 552,888 [C. A. 26, 5573 (1932)]-... 

Lauryl Alcohol (to, 62) By the reduction of ethyl laurate at 260° over a nickel catalyst. Palfray and Sabctay, Bull. soc. chim. (5) 3, 682 (1936). 

Fig. 131.—The reciprocal melting point plotted against the volume fraction of diluent for cellulose tributyrate in benzo-phenone ( ), in hydroquinone monomethyl ether (O), and in ethyl laurate (A). (Mandelkern and Flory. )...

Hydroquin one monomethyl ether Dimethyl phthalate Ethyl benzoate Ethyl laurate... 

Ethyl laurate-water Pore size = 0.2 fim, Product name Celgard 2400, Hoechst 116... 

Ethyl laurate-water Molecular weight cutoff = 500Da, Product name BM5, Berghof 116... 

Membrane reactor Ethyl laurate hydrolysis Candida rugosa lipase 116... 

When the mixture has cooled to about 6o°, there are added from the separatory funnel, first, a solution of 114 g. (0.5 mole) of ethyl laurate (Note 3) in 150 cc. of absolute alcohol (Note 4), then 500 cc. more of alcohol, as rapidly as is possible (Note 5) without loss of material through the condenser. The time required for the addition of the ester solution and the alcohol is less than five minutes, usually two or three minutes. When the reaction has subsided, the flask is heated on a steam bath until the sodium is completely dissolved (Note 6). The mixture is then steam distilled to remove the toluene and ethyl alcohol. 

The ethyl laurate used was prepared by the alcoholysis of cocoanut oil and fractionation of the resulting esters. The material boiled at i27-i32°/5 mm. 

Ethyl hydrogen sebacate, 21, 48 electrolysis of, 21, 48 Ethyl isothiocyanate, 21, 82 Ethyl lactate, 21, 71 Ethyl laurate, 20, 69 Ethyl linoleate, 22, 77 Ethyl linolenate, 22, 83 Ethyl malonate, 23, 16 Ethyl mercaptan, 22, 59 Ethyl 1V-methyl-/3-aminopropionate, 20, 37... 

This procedure has been used successfully for many years in the preparation of ethyl laurate, caprylate, and myristate by the alcoholysis of cocoanut oil (1 kg.) in ethanol (1900 g.) with hydrogen chloride (50 g.) as a catalyst.3 The method differs slightly from the one described above. The alcoholysis is complete after fifteen or twenty hours, and the solution is then neutralized to methyl orange with barium carbonate. The mixture is added to an equal volume of a saturated sodium chloride solution, whereupon 1100-1300 g. of the mixture of crude ethyl esters separates. This mixture of esters is washed with water and fractionated as described above. The yields are approximately 50 g. of ethyl caprylate, 350 g. of ethyl laurate, and 60 g. of ethyl myristate from 1000 g. of cocoanut oil. 

Novozym 435 (CAL-B, gift from Novo Nordisk, Denmark) (1.5 g) ethyl laurate (2.64 g, 11.6 mmol)... 

A solution of 2-aminooctane (1 g, 7.7 mmol), ethyl laurate (2.64 g, 11.6 mmol), Ndl-diethyl-2-mercapto-propionamide (1.49 g, 9.2 mmol) and Novozym 435 (1.5 g) in heptane (77 mL) was heated for 8 h at 80 °C in the presence of AIBN (the overall quantity of 30 mol% of AIBN (430 mg, 2.7 mmol) was divided into four equal portions that were added successively every 2 h). 

Laurone has been prepared by hydrating and decarboxylating decylketene dimer.3 It has also been prepared by distilling calcium laurate 4 by heating lauric acid with phosphorus pent-oxide 5 by heating barium laurate under reduced pressure 6 by the ester condensation of ethyl laurate with sodium ethoxide 7 or of methyl laurate with sodium hydride 8 followed by ketonic hydrolysis by catalytic ketonization of lauric acid over a chromate catalyst 9 or by passing lauric acid over thorium dioxide at 400°.10... 

Ethyl Laurate FEMA No. 2441 Ethyl Dodecanoate 228.38/C, 4H2802/ CH3(CH2)10COOC2H5 colorless, oily liq/ fruity-floral m—ale, chloroform, ether ins—water/ 269° 1 mL in 9 mL 80% ale gives clear soln... 

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