Ethers formamides

B. Reactions with Imido Esters, O-Alkyllactim Ethers, Formamide, and... 

Acetic acid, acetone, acetonitrile, benzenerwater (1 1), chloroform, cyclohexanone, dichloroacetice acid, dichloromethane, N,N-dimethylacetamide, dimethyUormainide, dimethylsulfoxide, dioxane, ethanol, ethylene glycol monomethyl ether, formamide, formic acid, 2-hydroxyethyl methacrylate, isopropanol, methanol, 2-methoxyethanol, methyl ether ketone, morphloline, 2,2 -oxydiethanol, 1-penlanol, phenol, 1,2-propanediol, 1-propanol, propylene glycol, pyridine, letrahydrcrfuran, trielhyl phosphate, trifluoroacelic acid, trimelhyl phosphate, water ... 

Dimethyl formamide Ethylene carbonate Ethylene glycol dimethyl ether Formamide 3-Methoxypropionitrile... 

Non-solvent acetonitrile, alcohols, chlorinated hydrocarbons, diethyl ether, formamide, hydrocarbons, ketones, methanol ... 

Formats s. a-Nitroformals —, mixed s. Alkoxymethyl ethers Formamide... 

The physical properties of finish removers vary considerably due to the diverse uses and requirements of the removers. Finish removers can be grouped by the principal ingredient of the formula, method of appHcation, method of removal, chemical base, viscosity, or hazardous classification. Except for method of apphcation, a paint remover formulation usually has one aspect of each group, by which it can be used for one or more appHcations. A Hst of the most common organic solvents used in finish removers has been compiled (3). Many are mentioned throughout this article others include ethyl lactate [97-64-3] propylene carbonate [108-32-7] furfural alcohol [98-01-1/, dimethyl formamide [68-12-2] tetrahydrofuran [109-99-9] methyl amyl ketone [110-43-0] dipropylene glycol methyl ether [34590-94-8] and Exxate 600, a trade name of Exxon Chemicals. 

Dimethyl formamide with cyclohexane or petroleum ether. 

Petroleum ether with aniline, benzyl alcohol, dimethyl formamide, dimethyl sulfoxide, formamide, furfuryl alcohol, phenol or water. 

Dimethyl formamide with benzene, ethanol or ether. 

A. p-Xylylene-bis(lriphenylphosphonium chloride). A mixture of 262 g. (1.0 mole) of triphenylphosphine (Note 1) and 84 g. (0.48 mole) of J)-xylylene dichloride (Note 2) in 1 1. of dimethyl-formamide is heated at reflux with stirring for 3 hours (Note 3). The mixture is then allowed to cool to room temperature with stirring, and the white crystalline solid is collected, washed with 100 ml. of dimethylformamidc followed by 300 ml. of ether, and... 

A mixture of 3.18 g (10 mmoles) of 17 -hydroxy-2-hydroxymethylene-5a-androstan-3-one, 20 ml dry dimethyl formamide and 0.3 g (13 mmoles) of sodium hydride is stirred for 0.5 hr at room temperature under nitrogen. A total of 1.51 g (12.5 mmoles) of redistilled allyl bromide is added and the mixture is stirred for 1 hr on the steam bath. Aqueous potassium hydroxide (2 g in 5 ml of water) is added and stirring is continued for 1 hr on the steam bath. The reaction mixture is diluted with 50 ml of methylene dichloride followed by careful addition of 300 ml of water. The organic phase is separated and the aqueous phase is again extracted with 50 ml of methylene dichloride. The combined extracts are washed with water, dried over sodium sulfate, filtered and chromatographed on 200 g of silica gel. Elution with pentane-ether (4 1) provides 2a-allyl-17j -hydroxy-5a-androstan-3-one 0.85 g (26%) mp 118-119° [aj 14° (CHCI3), after crystallization from ether-hexane. 

Dehydrochlorination of bis(tnfluoromethylthio)acetyl chloride with calcium oxide gives bis(trifluoromethylthio)ketene [5] (equation 6) Elimination of hydrogen chloride or hydrogen bromide by means of tetrabutylammonium or potassium fluoride from vinylic chlorides or bromides leads to acetylenes or allenes [6 (equation 7) Addition of dicyclohexyl-18-crown-6 ether raises the yields of potassium fluoride-promoted elimination of hydrogen bromide from (Z)-P-bromo-p-ni-trostyrene in acetonitrile from 0 to 53-71 % In dimethyl formamide, yields increase from 28-35% to 58-68%... 

By a more detailed study of the reaction of 5-azauracil with diazo-methane it was found that this reaction is considerably accelerated by the presence of a small amount of water, methanol, or dimethyl-formamide. It does not proceed appreciably in absolute ether. By... 

Aj Preparation of 3-Chloromethyl-6-Chloro-7-Sulfamyl-3,4-Dihydro-Benzothiadizine-1,1-Dioxide—Jo 8 ml of 40-50% chloroacetaldehyde aqueous solution and 7 ml of dimethyl-formamide are added 10 grams of 2,4-disulfamvl-5-chloroaniline. The mixture is heated on a steam bath for 2 hours after which it Is concentrated at reduced pressure. The residue Is triturated with water. The solid material is recrystallized from methanol-ether after-treatment with activated carbon to give 7.2 grams of product, MP 229°-230°C. 

The characteristics of this product are as follows. It is a pale yellow, nonodorous, slightly bitter, crystalline powder, very soluble in water (>1.5 g/cc), soluble in methanol and formamide, slightly soluble in ethanol and isopropanol, insoluble in ether, benzene and chloroform MP 162° to 163°C with decomposition uncorrected). 

To the mixture of 85.5 g ethyl a-(3chloro-4.aminophenyl)-propionate hydrochloride, 142 g sodium carbonate and 600 ml dimethyl formamide, 107 g 1,4room temperature. The mixture is filtered, the filtrate evaporated in vacuo, the residue is triturated with hexane, the mixture filtered, the residue washed with petroleum ether and the filtrate evaporated. The residue is combined with 280 ml 25% aqueous sodium hydroxide and the mixture refluxed for 8 hours. After cooling, it is diluted with water, washed with diethyl ether, the pH adjusted to 5 to 5.2 with hydrochloric acid and extracted with diethyl ether. The extract is dried, filtered, evaporated and the residue crystallized from benzene-hexane, to yield the a-(3-chloro-4-pyrrolinophenyl)-propionic acid melting at 94°C to 96°C. 

A. N,N-Dimeihyljormamide-dimelhyl sulfate complex. In a 500-ml. four-necked flask equipped with mechanical stirrer, reflux condenser with calcium chloride drying tube, dropping funnel, and thermometer is placed 73 g. (1.0 mole) of dimethyl-formamide, and 126 g. (1.0 mole) of dimethyl sulfate is added dropwise with stirring at 50-60° (Note 1). After the addition is complete, the mixture is heated for another 2 hours at 70-80°. The dimethylformamide complex forms as a viscous, colorless or pale yellow ether-insoluble oil. 

Aldehydes, formates, primary, and secondary alcohols, amines, ethers, alkyl halides, compounds of the type Z—CH2—Z, and a few other compounds add to double bonds in the presence of free-radical initiators/ This is formally the addition of RH to a double bond, but the R is not just any carbon but one connected to an oxygen or a nitrogen, a halogen, or to two Z groups (defined as on p. 548). The addition of aldehydes is illustrated above. Formates and formamides " add similarly ... 

Cyanogen chloride 0.25/a Cyclohexane 100/a Diethyl ether 100/a Dimethyl formamide 10/b Dimethyl sulphate 0.005/c Dimethyl sulphide 1/a Epichlorohydrin 5/b Ethyl acetate 200/a Ethyl benzene 30/p... 

The reaction of brominated diphenyl ethers with methoxide in dimethyl formamide has been examined, and suggested as a ranking of their susceptibility to hydrolytic reactions under natural conditions (Rahm et al. 2005). The nature of the products was not apparently systematically examined. 

---