Escherichia coli antimicrobials effective against

Mechanism of Action An antitubercular that inhibits DNA-dependent RNA polymerase, an enzyme in susceptible strains of Escherichia coli and Bacillus subtilis. Rifabutin has a broad spectrum of antimicrobial activity including against mycobacteria such as Mycobacterium avium complex (MAC). Therapeutic Effect Prevents MAC disease. 

Nanavaty J, Mortensen J E, Shryock T R 1998 The effects of environmental conditions on the in vitro activity of selected antimicrobial agents against Escherichia coli. Current Microbiology 36 212-215... 

Karamenderes et al. [67] reported the composition and antimicrobial activity of the essential oils obtained from Achillea millefolium L. subsp. pannonica (Scheele) Hayek, Achillea millefolium subsp. millefolium, Achillea arithmifolia Waldst Kitt and Achillea kotschyi Boiss. subsp. kotschyi, four Achillea species from Turkey. 1,8-cineole, Fig. (2), artemisia alcohol and ascaridole were identified as major components. The essential oils showed antibacterial and antifungal effects even with low concentrations. The essential oil of the flowering tops of another Achillea species, Achillea fragantissimum (Forsk.) Sch. Bip growing in Sinai, was analyzed [68]. Santolina alcohol, a- and P-thujone, Fig. (5) and artemisia ketone account for approximately 80% of the oil. The oil showed marked antimicrobial activities against Escherichia coli. Bacillus subtilis and Staphylococcus aureus. 

The antimicrobiai activity of CHG is pH dependent, with an optimal use range of 5.5-7.0, a nice consistent match with the body s usuai range of pH. However, the relationship between antimicrobial effectiveness of CHG and pH varies with the microorganism. For example, CHG s antimicrobial activity against Staphylococcus aureus and Escherichia coli increases with an increase in pH, but the reverse is true for Pseudomonas aeruginosa. 

---