Ergometrine tartrate

In some cases hydrochloride salts are not very water soluble due to the strength of association between the base and its counter ion, and other salts have to be used. For instance, salts may be prepared with di- or tricarboxylic acids, e.g. ergometrine tartrate, diethylcarbamazine citrate, sumatriptan succinate (Fig. 3.18) and lisuride maleate are all used because of the water insolubility of their hydrochlorides. Similarly strong monobasic organic acids such as mesilate are used to promote water solubility, as in the case of benzatropine mesilate (Fig. 3.18) andphentol-amine mesilate. In some instmces salts are too ready to absorb water from the atmosphere, for instance the muscle relaxant dmg atracurium is formulated as its besilate salt to avoid the problems of water absorption experienced with its mesilate. 

Their reaction was tested on the individual components of the test mixture indole, ergotamine tartrate, ergotaminine and ergobasine [ergometrine) [3]. The results obtained were as follows ... 

Lysergic acid diethylamide (LSD) LSD in illicit preparations containing ergot alkaloids like iso-LSD, ergometrine maleate, ergocryptinine base and ergotamine tartrate Partition p.-Bondapak C18/ Corasil Methanol/0.1 per cent ammonium carbonate (60 40)... 

The tartrate of an alkaloid obtainable from certain species of ergot. It is assayed colorimetrically by the dimethylaminobenzaldehyde method given under Ergot after solution in 1 per cent tartaric acid against a standard ergometrine maleate solution. 1 mg of ergometrine maleate = 1 488 mg of ergotamine tartrate. 

---