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Endothelial Tumors

Anti-CD34 (M) Dako 1 800 MWER Recognition of endothelial tumors, dermatofibrosarcoma protuberans, solitary fibrous tumors, and selected peripheral nerve sheath tumors and epithelioid sarcomas... [Pg.88]

Anti-CD31 (M) Dako 1 40 MWER Recognition of endothelial tumors... [Pg.88]

Anti-L//ex europaeus 1 lectin (P) Dako 1 4000 NT Recognition of endothelial tumors via binding of Ulex europaeus 1 lectin... [Pg.88]

The usual approach to characterization of a vascular tumor is to employ a battery of endothelial-selective markers together with several reagents directed at epithelial and muscle-related determinants. That is because selected endothelial tumors may histologically simulate carcinomas or sarcomas with myogenic differentiation... [Pg.486]

Lesions classified as hemangioendotheliomas, generally conceptualized as borderline endothelial tumors, have increased in number in recent years. [Pg.487]

Tissue-type plasminogen activator (tPA) is a glycoprotein (68 kDa), synthesized by endothelial and tumor-cells. As a serine protease, tPA hydrolyses Arg561-Val562 peptide bond in plasminogen, resulting in plasmin formation. It needs cofactors for efficient plasminogen activation. [Pg.1202]

Urokinase-type plasminogen activator (uPA, urokinase) is synthesized by endothelial and tumor cells as a single-chain glycoprotein (scuPA) without catalytic activity. When it is converted to a two-chain protein (tcuPA) by plasmin, an active serine protease center develops, which activates plasminogen. Thus, uPA (55 kDa) results in the amplification of fibrinolysis. [Pg.1268]

Ahn SY, Cho CH, Park KG, Lee HI, Lee S, Park SK, Lee IK, Koh GY (2004) Tumor necrosis factor-alpha induces fractaUdne expression preferentially in arterial endothelial cells and mithramycin A suppresses TNF-alpha-induced fractaUdne expression. Am J Pathol 164 1663-1672 Alfano M, Schmidtmayerova H, Amelia CA, Pushkarsky T, Bukrinsky M (1999) The B-oligomer of pertussis toxin deactivates CC chemokine receptor 5 and blocks entry of M-tropic HIV-1 strains, [see comments]. J Exp Med 190 597-605 Ambrosini E, Alois F (2004) Chemokines and glial cells a complex network in the central nervous system. [Review] [239 refs]. Neurochem Res 29 1017-1038 Azuma Y, Ohura K (2002) Endomorphins 1 and 2 inhibit IL-10 and IL-12 production and innate immune functions, and potentiate NE-kappaB DNA binding in THP-1 differentiated to macrophagelike cells. Scand J Immunol 56 260-269... [Pg.332]

Activated T cells begin releasing cytokines including interleukin-2 (IL-2), interferon-y, (IFN-y), tumor necrosis factor (TNF-a), and others.4,13 Cytokine activity leads to a rapid proliferation and turnover of skin cells, triggering the inflammatory process and the development of psoriatic skin lesions.4,13,14 TNF-a may have a role in disease severity it upregulates endothelial and keratinocyte expression of ICAM-1,... [Pg.950]

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