Emil Fischers Research

Whereas the configurations of the sugars are truly a lasting monument to Emil Fischer, the concept of asymmetric induction, also referred to as partial asymmetric synthesis, initiated a new era in chemical research that is still with us today. 

Geison, "Scientific Change." J. S. Fruton, "Contrasts in Scientific Style Emil Fischer and Franz Hofmeister, Their Research Schools and Their Theories of Protein Structure," Proceedings of the American Philosophical Society 129 (1985) 313370 also see, Fruton, "The Liebig Research Group, a Reappraisal," ibid., 132 (1988) 166 Holmes, "Complementarity," 121164 and J. B. Morrell, "The Chemist Breeders ... 

Fruton, Joseph S. "Contrasts in Scientific Style Emil Fischer and Franz Hofmeister Their Research Schools and Their Theories of Protein Structure." Proceedings of the American Philosophical Society 129 (1985) 313370. 

It was emphasized above that, during the course of his experimental work, Emil Fischer had to create new concepts on which to base further exploratory research. A few examples of this will now be cited. 

FISCHER, HANS (1881-1945). A German biochemist who studied under Emil Fischer. He was awarded the Nobel prize in chemistry in 1930 lor his synthesis of the blood pigment hcmin. He also did important fundamental research on chlorophyll, and porphyrins, and carotene. 

The researchers Joseph von Mering and Emil Fischer, a student of von Baeyer, developed the first barbiturate drug to be marketed. Fischer produced 5.5-diethylbarbituric acid, a hypnotic (medication to help patients sleep) and sedative (medication to relax people with constant nervousness and anxiety). This sedative/hypnotic drug was known by the trade names Barbital, Veronal, and Dorminal. Barbital proved to be a more effective sedative/hypnotic agent and replaced the class of drugs, sedative bromides, which were used at the time.14... 

Kunz, H. "Emil Fischer - Unequalled Classicist, Master of Organic Chemistry Research, and Inspired Trailblazer of Biological Chemistry". Angew. Chem. Int. Ed. 41,4439-4451 (2002). 

Kunz H (2002) Emil Fischer-Unequalled classicist, master of organic chemistry research, and inspired trailblazer of biological chemistry. Angew Chem fnt Ed Engl 41 4439 1451... 

The period during which the foundations of present carbohydrate nomenclature assumed a systematic form covers the years 1890-1895 the system is due to Emil Fischer and its conventions were devised by him because they were necessary for clarity in the description of his sugar researches. His main proposals for nomenclature were made in successive steps during this period, and a study of the order of the historical record leaves no doubt that the subject assumed form in his mind by... 

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