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Drugs, role

Frecer, V., Maliar, T. and Miertus, S. (2000) Protease inhibitors as anticancer drugs role of molecular modelling and combinatorial chemistry in drug design. Int. J. Med. Biol. Environ. 28 161-173. [Pg.443]

Kashiyama, E. Yokoi, T. Todaka, T. Odomi, M. Kamataki, T. Chiral inversion of drug role of intestinal bacteria in the stereoselective sulphoxide reduction of flosequinan. Biochem. Pharmacol. 1994, 48,... [Pg.399]

Binds lidocaine, propanolol, drugs Role in immune system Modifies platelet aggregation Polymorphism with no clinical significance... [Pg.5284]

Requirements and Problems in Urin-analysis for Abuse Drugs. Role of Gas Chromatography Am. J. Med. Technol. 39(6) 205-210 (1973) CA 79 101163s Review... [Pg.216]

The interpretation of molecular surfaces is particularly important wherever molecular interactions, reactions, and properties play a dominant role, such as in drug design or in docking c.xpcrimcnts. [Pg.125]

Following the similar structure - similar property principle", high-ranked structures in a similarity search are likely to have similar physicochemical and biological properties to those of the target structure. Accordingly, similarity searches play a pivotal role in database searches related to drug design. Some frequently used distance and similarity measures are illustrated in Section 8.2.1. [Pg.405]

The development of a new drug is both a time-consuming and a cost-intensive process. It takes 12 to 15 years and costs up to 800 million to bring a new drug to the market. As measured by the market capitalization, the pharmaceutical companies play a pivotal role in the global economy. In February 2003 Pfizer was ranked at position five worldwide, with a market capitalization of 163 billion. Ranking third as far as the market capitalization in Europe is concerned was GlaxoSmithKline, with a current value of 101 billion. Novartis was number five in Europe with 82 billion. [Pg.598]

Chemoinformati.cs is involved in the drug discovery process in both the lead finding and lead optimization steps. Artificial neural networks can play a decisive role of various stages in this process cf. Section 10.4.7.1). [Pg.602]

Raman spectraof [INFRARED TECHNOLOGY AND RAMAN SPECTROSCOPY - RAMAN SPECTROSCOPY] (Voll4) -role in drug delivery pRUG DELIVERY SYSTEMS] (Vol 8)... [Pg.85]

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See also in sourсe #XX -- [ Pg.56 ]



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Clinical evaluation, drugs roles

Drug absorption colon role

Drug development process stability role

Drug development roles

Drug disposition, role

Glutathione, drug resistance role

Its Roles in Transdermal Drug Delivery

Melanin Play a Role in Drug Binding

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Pharmaceutical drug development separation science role

Physiological Roles of Drug Transporting ABC Proteins - Search for Substrates

Potency, drugs cell membrane role

Potency, drugs receptor role

Prostaglandins , drugs, role

Role of Covalent Binding in Drug Toxicity

Role of Lipophilicity in Drug Clearance

Role of Outsourcing in Drug Manufacture

Role of Polymers in Ternary Drug Cyclodextrin Complexes

Role of Transporters in Drug Absorption

Role of Transporters in Drug Distribution

Role of Transporters in Drug Interactions

Role of the Drugs

Role of the Orphan Drug Act

Role of water in drug-DNA intercalation

The Central Role of Cardiovascular Safety in Drug Development and Therapeutic Use

The Expanding Role of HPLC in Drug Discovery

The Role of Drug Transporters in RE Development

The Role of Functional Groups in Drug-Receptor Interactions

The Role of Liquid Chromatography-Mass Spectrometry in Pharmacokinetics and Drug Metabolism

The Role of Synthetic Chemistry in Drug Discovery

The role of clinical trials in new drug development

The role of statistics In drug development

Thomas R. Cech 2 The Role of PharmacogeneticsPharmacogenomics in Drug Development and Regulatory Review Current Status

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