Drug quantitation

Ding J. and Neue U.D., 1999. A new approach to the effective preparation of plasma samples for rapid drug quantitation using online solid phase extraction mass spectrometry. Rapid Commun Mass Spectrom 13 2151. 

Dexketoprofen Gel Non-destructive drug quantitation method of a hydrogel in transflectance mode 35... 

Fink, M. Classification of psychoactive drugs quantitative EECi analysis in man. In Van Praag, H.M., et aL (eds) Handbook oj Biological Psychiatry, Part VI. Marcel Dekker, New York, 1981, pp. 309-326. 

In the present study various surface measurements were made on interfacial lipid films to analyze in more detail the nature of interactions of lipids, Ca2+, ATP, and the glycolate esters. Surface pressure-area and surface potential-area diagrams were obtained on surface films of stearic acid, lecithin, and a mixture of brain lipids with Ca2+, ATP, and the drugs present in the subsolution, individually or in combination. Using radioactive Ca2+, ATP, and drug, quantitative measurements were made on the surface adsorption of these substances to lipid films. In addition, electron microscopy was performed on brain lipid films formed in the presence or absence of Ca2+ and ATP. Our objective was to establish the existence of surface complexes involving these substances with the hope... 

Taki, Y., et al. 1995. Gastrointestinal absorption of peptide drug Quantitative evaluation of the degradation and permeation of metkephamid in rat small intestine. J Pharm Exp Therapeut 274 373. 

Key words Plasmodium falciparum, Kinase, Drug, Quantitative structure-activity relationships, Pharmacophore, Docking, Antimalarials... 

Ding J, Neue UD (1999) A New Approach to the Effective Preparation of Plasma Samples for Rapid Drug Quantitation of Plasma Samples for Rapid Drug Quantitation Using On-line Solid Phase Extraction Mass Spectrometry. Rapid Communications in Mass Spectrometry 13 2151-2159... 

C E Pipftei er et al. Antiepilephc Dn Levels Quality Control Program Interlaboratory alxlity, mAntieptleptic Drugs Quantitative Analysts and Interpretation,C E Pi pengere/a/ (Ed),New Y k, Raven Press, 1978, p 187-197... 

K.H. Dudley, C.E. Pippenger, J.K. Panry, H. Kutt, Antiepileptic Drugs Quantitative analysis and interpretation, Raven Press, New York, 1978. 

Many instances of parent drug quantitation are illustrated throughout this book. In some cases, the quantitation of metabolites is also warranted. Quantitation of metabolite is necessary when the metabolite is either toxic or pharmacologically active or when the concentrations of metabolite reach or exceed the parent drug concentration in plasma. The latter case can be important because total drug exposure is more an exposure to metabolite than parent drug and most safety and efficacy parameters are in relation to plasma exposure. 

Tiller, P.R. et al., Drug quantitation on a benchtop liquid chromatography-tandem mass spectrometry system, J. Chromatogr. A., Ill, 119, 1997. 

Dinman BD, Chaffin DB Surface electromyography in chronic inorganic mercury intoxication, in Adverse Effects of Environmental Chemicals and Psychotropic Drugs Quantitative Interpretation of Functional Tests, Vol 1. Edited by Horvath M. Amsterdam, Elsevier, 1973, pp 165-169 Dodes JE The amalgam controversy an evidence-based analysis. J Am Dent Assoc 132 348-356, 2001... 

A second fundamentally important area of research, in which the influence of temperature was poorly understood, and in which an influence of hydrostatic pressure was unknown, was the physiological and biochemical action of narcotics and other drugs. Quantitative interpretations were attempted through various hypotheses, based for example on correlations between potency of action and solubility of the drug in olive oil, and distribution of the drug between water and olive oil at different temperatures.Other theories were based on partial agreement of quantitative effects with adsorption isotherms or on specific properties of the drug. - ... 

Turnpenny P, Fraier D, Chassaing C, Duckworth J. Development of a micro-turbulent flow chromatography focus mode method for drug quantitation in discovery bioanalysis. J Chromatogr B Anal Technol Biomed Life Sci 2007 856 131-140. 

Liu RH, Lin T-L, Chang W-T, et al. (2002) Isotopically labeled analogues for drug quantitation. Analytical Chemistry 74 618A-626A. 

Herbal Identity, purity, and stability tests of plant drugs Quantitation of marker compounds... 

In summary, despite the significant challenges associated with LC-MS/MS-based assays for protein drug quantitation, these assays stiU show promise as an emerging complementary technique for protein bioanalysis. 

Abuse and Target Drug Quantitation in Urine/Blood Matrices. 29... 

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