Drug utilization

Goldberg Arnold R, Kaniecki D. Health economic considerations in cardiovascular drug utilization. In Frishman W, Sonnenblick E, editors. Cardiovascular pharmacotherapeutics. New York McGraw-Hill, Inc., 2003. pp. 43-55. 

Procyshyn RM, Zerjav S (1998). Drug utilization patterns and outcomes associated with in-hospital treatment with risperidone or olanzapine. Clin Ther20, 1203—17. 

General Drug Utilization Principles in Intensive Care... 

Luo, N. et al. (2004). Drug utilization review of risperidone for outpatients in a tertiary referral hospital in Singapore. Hum. Psychopharmacol, 19, 259-64. 

R. B. Wallace, Drug utilization in the rural elderly Perspectives from a population study, in Geriatric Drug Use—Clinical and Social Perspectives (S. R. Moore and R. W. Teal, eds.), Permagon Press, New York, 1985, pp. 78-85. 

DC Brodie. Drug utilization review/planning. Am J Pub Health 46 103, 1972. 

Despite the scientific elegance of the antibody-mediated approach to tumour detection/destruc-tion, initial clinical trials proved disappointing. A number of factors contributed to their poor therapeutic performance, particularly against solid tumours. Most such factors relate directly/ indirectly to the fact that the first generation of such drugs utilized whole monoclonal antibody preparations of murine origin. These factors include ... 

A few studies have examined the impacts of Medicaid and non-Medicaid copayments on drug utilization and health care costs. In a 1993 study, Reeder et al. noted an 11% decrease in prescription use after South Carolina established a 50-cent per prescription copayment. This increase was significantly greater than in Tennessee, a comparison state with no copayments (Reeder et al., 1993). Another study using survey data from the 1992 Medicare Beneficiary Survey found that elderly and disabled Medicaid beneficiaries who live in states with prescription drug copayments have lower prescription drug utilization than their counterparts in states without copayment, and three-fourths of the difference was directly attributed to copayment policies. The study predicted that Medicaid copayments... 

Blalock SJ, Byrd JE, Hansen RA et al. (2005) Factors associated with potentially inappropriate drug utilization in a sample of rural community-dwelling older adults. Am 1 Geriatr Pharma-cother 3(3) 168-179... 

The evolving structural insights into the hERG drug-binding site show that this channel has a relatively larger inner cavity, with many aromatic and polar residues intricately positioned to interact with drugs. Utilization of in silico techniques, refined... 

Despite the promising applications of PK and PK/PD modelling in many fields of drug research [3,49] and drug utilization [29], awareness of their limitations is necessary. Among others, the following aspects may interfere with successful PK and PK/PD modelling and analy-... 

As the ultimate goal of pharmacoepidemiology is to improve the rational use of drugs, the applications of the field to achieve that goal are quite broad. Here, we divide the applications into four major areas for improving the rational use of dmgs efficacy, safety, cost-effectiveness, and drug utilization. 

Focused drug use evaluation (drug utilization review) can be done to identify problems concerning the use of specific medicines or the treatment of specific diseases, particularly in hospitals. The qualitative methods employed in social science (e.g. focus group discussion, in-depth interviews, structured observation and structured questionnaires), can be used to investigate the motives underlying irrational use. All data collected should be used to design interventions and to measure the impact of those interventions on medicine use. 

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