Drug resistance gene

Kioka, N., Hosokawa, N., Komano, T., Hiiayoshi, H., Nagat, K., Ueda, K. (1992). Quercetin, a bioflavonoid, inhibits the increase of human multi-drug resistance gene (MDRI) expression caused by arsenite. FEES Lett. 301, 307-309. [Pg.456]

PETERSON G and BARNES s (1991) Genistein inhibition of the growth of hiunan hreast cancer cells independence from estrogen receptors and the multi-drug resistance gene. Biochem Biophys Res Commun. 179 (1) 661-7. [Pg.218]

Hoffmeyer S, Burk O, Von Richter O, Arnold HP, Brockmoller J, Johne A et al. Functional polymorphisms of the human multi-drug resistance gene multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc Natl Acad Sci USA 2000 97 3473-3478. [Pg.335]

Schluter A, Szczepanowsld R, Puhler A et al (2007) Genomics of IncP-1 antibiotic resistance plasmids isolated from waste water treatment plants provides evidence for a widely accessible drug resistance gene pool. KEMS Microbiol Rev 31(4) 449-477... [Pg.211]

This is known to be mediated in some instances by the multi-drug resistant gene (MDRl) producing the /J-glycoprotein, where /(-glycoprotein expression was associated with a decrease in intracellular IM levels and development of resistance (37). [Pg.136]

Multiple drug resistance gene 1 (mdr-1) Chemotherapy-induced [86]... [Pg.272]

Panwala CM, Jones JC, Viney JL. A novel model of inflammatory bowel disease mice deficient for the multiple drug resistance gene, mdrla, spontaneously develop colitis. J Immunol 1998 161 5733-5744. [Pg.147]

A recent successful application of the shRNA barcode approach for drug resistance genes was completed. The authors used RNAi to identify for genes that conferred resistance to trastuzumab... [Pg.158]

Shi, R. et al. Temperature-mediated heteroduplex analysis for the detection of drug-resistant gene mutations in clinical isolates of Mycobacterium tuberculosis by denaturing HPLC, SURVEYOR nuclease. Microb. Infect. 2006, 8, 128-135. [Pg.123]

Zhao JY, Ikeguchi M, Eckersberg T et al. Modulation of multi-drug resistance gene expression by dexam-ethasone in cultured hepatoma cells. Endocrinology 1993 133 521-8. [Pg.246]

Fojo, A.T. Ueda, K. Slamon, D.J. Poplack, D.G. Gottesman, M.M. Pastan, M.M. Expression of a multi-drug-resistance gene in human tumors and tissues. Proc. Natl. Acad. Sci. USA 1987, 84, 265-269. [Pg.589]

Distribution and chemical induction of multiple drug resistance genes in rats. Drug Metabolism and Disposition The Biological Fate of Chemicals, 30, 838-844. [Pg.219]

P-glycoprotein (P-gp) is an ATP-dependent drug efflux pump. In humans, P-gp is encoded by the multi-drug resistance gene (MDR-1) that is located on the long arm of chromosome 7. Overexpression of P-gp in neoplastic cells is associated with the phenomenon of multidrug resistance to chemotherapeutic agents... [Pg.631]

Akache. B., MacPherson, S., Sylvain, M.A.. and Turcotte, B. (2004) Complex interplay among regulators of drug resistance genes in Saccharomyces cerevisiae. The Journal of Biological Chemistry, 279. 27855-27860. [Pg.185]

Karnani, N., Gaur, N.A., Jha, S., Puri, N., Krlshnamurthy, S., Goswami, S.K., Mukhopadhyay, G., and Prasad, R. (2004) SREl and SRE2 are two specific steroid-responsive modules of Candida drug resistance gene 1 (CDRl) promoter. Yeast, 21, 219-239. [Pg.187]

M., Cucullo, L.. Goodrich. K., Bingaman, W., Mayberg, M.R., Bengez, L. etal. (2001) Overexpression of multiple drug resistance genes in endothelial cells from patients with refractory epilepsy. Epilepsia, 42, 1501-1506. [Pg.296]

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