Djerassi, Carl

Daub, Guido H., 6 Dave, Vinod, 18 Davies, Huw M. L., 57 Davis, Franklin A., 62 Denmark, ScoU E., 45 Denny, R. W., 20 DeLucchi, Ottorino, 40 DeTar, DeLos R, 9 Dickhaut, J., 48 DJerassi, Carl, 6 Donaruma, L, Guy, 11 Drake, Nathan L., I DuBois, Adrien S., 5 Ducep, Jean-Bemard, 27 Dunogu s, Jacques, 37... 

Djerassi, Carl. This Man s Pill Reflections on the 50th Birthday of the Pill. New York Oxford University Press, 2001. This is a highly personahzed history of the development of the birth control pill by the person often termed the father of the birth control pill. ... 

Djerassi, Carl, and Roald Hoffmann. Oxygen. Weinheim Wiley-VCH,... 

Djerassi, Carl (1923- ) Austrian-born American chemist. The first notable work which he and his colleagues at Syn-tex, in Mexico City, performed was to extract cortisone from a vegetable source. Djerassi and his colleagues then investigated the steroid hormone progesterone... 

We wish to thank Professor Carl Djerassi for suggesting that we undertake this effort. We are especially grateful to Drs. N. Dyson, C. Djerassi, I. T. Harrison and J. Pfister, each of whom reviewed the final draft of one of the chapters. Secretarial help by Miss Mary Jakubauskus is also gratefully acknowledged. 

Steroid chemistry, the glamor area of natural product research in the years following World War II, was replaced by macrolides, alkaloids, and prostanoids. Sterol chemistry again became exciting when an unanticipated rich diversity of marine invertebrate sterols were isolated, notably from sponges. After pioneering research in Italy, the field was reborn in Carl Djerassi s laboratory at Stanford. As a result, we now have a better and more detailed knowledge of sterol biosynthesis than of any other class of marine natural products. The authors of Chapter 1 are Stanford alumni. 

It is not often that current research is featured in a popular novel. Carl Djerassi [231] wrote in 1998 a science-in-fiction book, NO, where the principal character, Renu Krishnan, a molecular biologist, discovers that salts formed by reacting certain nucleophiles with the bioregulatory agent nitric oxide (NO) can regenerate pharmacologically active NO on contact with body fluids and can treat erectile dysfunction. 

Personal letter from S. S. Schweber, 20 April 1992. Also, [Lord] Alexander Todd, "Summing Up," in Further Perspectives in Organic Chemistry. Ciba Foundation Symposium 53 (new series). To Commemorate Sir Robert Robinson and His Research (Amsterdam Elsevier, 1978) 203204 and Carl Djerassi, lecture at University of Oklahoma, Norman, 19 November 1992. 

Studies on isolation from adrenal cortex and the synthesis of cortisone (in 28 steps), an anti-arthritic hormone, was accomplished in the 1940s by Woodward and others. Cortisone was used as an important military medicine during World War II. Carl Djerassi from Stanford University directed the research at the Syntex Laboratories, which led to the synthesis of the first oral contraceptive pill for women. Koji Mori is very active in the field of the synthesis of pheromones. 

The next great chemist to take up the challenge of making other human steroids was the Austrian-born Carl Djerassi, who fled his coimtry after the Nazi invasion in iggS, and joined the Swiss owned CIBA company in New York. He subsequently joined Syntex (now a respectable company after that shady start) and devised a way of making cortisone from extracts of Mexican yams or sisal. However, the Syntex synthesis of cortisone was never commercially successful because a competing method, involving the use of microbial fermentation, could provide a cheaper product. 

We wish to thank Professors Carl Djerassi, Albert Moscowitz and Gunther Snatzke, without whose pioneering work much of what is written in this chapter would not have been possible. Special thanks go to those authors, Professors Djerassi and J. F. King, and journals or books for allowing use of illustrations from their articles. 

C. Djerassi, The Pill, Pygmy Chimps, and Degas Horse The Autobiography of Carl Djerassi (New York Basic Books. 1992). 

Carl Djerassi, Roald Hoffmann Oxygen A Play in 2 Acts... 

Terms from the realm of inorganic chemistry rarely make it to the title of novels. This is true in particular for stories dealing exclusively with chemistry between people rather than chemistry between elements. NO (nitric oxide) by Carl Djerassi does not conform to this category, but Platinum Blues by William Deverell [1] surely does. To the unbiased reader the relationship between platinum and the blues (singular) in the music business may not be an obvious one, and consequently one wonders if the author, at some stage, may have had an encounter with inorganic chemistry. After all, comprehensive inorganic chemistry textbooks frequently refer to this class of blues (plural), which still provides an aura of fascination. 

Oestrone lacks one of progesterone s methyl groups, probably removed in the body as CO2 after oxidation. In 1946, Carl Djerassi, a man whose work led directly to the invention of the contraceptive pill, showed that another derivative of cholesterol could be rearranged to the oestrone analogue 1-methyloestradiol—notice how the methyl group has this time migrated to an adjacent carbon atom. At the same time, the dienone has become a phenol. 

Carl Djerassi, an American bom in Vienna in 1923, worked chiefly eft CIBA, Syntax in Mexico, and at Stanford, He developed syntheses of human steroids from compounds in plants, was a pioneer of mass spectrometry, and is a colourful campaigner for peace and disarmament. 

Tou have had a lot of interaction with Carl Djerassi. Are you also involved in biotechnology ... 

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