Dixon analysis

In our experience, drawing straight lines through the usual small number of data points, as carried out in the Dixon analysis, was not easy, particularly for the slope = 0 line. This ambiguity made it difficult to have confidence in the pAT values determined. The procedure developed in this chapter is more reliable. On the other hand, the pAT values obtained using the Dixon analysis and the analysis presented in this chapter were found to be similar (Fig. 6.6b). 

Caulcutt, R., and R. Boddy, Statistics for Analytical Chemists, Chapman and Hall, London, 1983. Dixon, W. J., and F. J. Massey, Introduction to Statistical Analysis, McGraw-Hill, New York, 1969. 

Dixon B (2005) Applicability of neuro-ftizzy techniques in predicting ground-water vulnerability a GIS-based sensitivity analysis. J Hydrol 309 17-38... 

FIGURE 9.3 Cross-linked recombinant resilin. (a) Structure of the dityrosine adduct, (b) A cross-linked moulded rod. (c) HPLC analysis of acid-hydrolyzed uncross-Unked recombinant resilin and cross-linked recombinant resilin. (From Elvin, C.M., Carr, A.G., Huson, M.G., Maxwell, J.M., Pearson, R.D., Vuocolo 1, T., Liyon, N.E., Wong, D.C.C., Merritt, D.J., and Dixon, N.E., Nature, 437, 999, 2005.)... 

Chen, L. and Dixon, K., Analysis of repair and mutagenesis of chromium induced DNA damage in yeast mammalian cells and transgenic mice, Environmental, Health Perspective, 106, 1027-1032, 1998. 

In the Mediterranean Sea and Middle East area, for example, there are obsidian outflows only in Italy, in some islands in the Aegean Sea, and in Turkey. Artifacts made of obsidian, however, are widely distributed over much of this vast area. Chemical analysis of many of these artifacts has shown that most of the obsidian used to make them originated in one or another of the outflows mentioned, but also in far-distant places such as Armenia and Iran. Plotting on a graph the concentration of selected elements in samples from obsidian sources against that in samples from sites where it was used, enables the identification of the source of the samples (see Fig. 22). Moreover, this type of analysis also makes it possible to trace the routes through which obsidian (and most probably other goods) were traded in antiquity (Renfrew and Dixon 1976). 

Dixon WJ, Massey, FJ (1969) Introduction to statistical analysis. McGraw-Hill, New York... 

Other reviews of multidimensional separations have been published. These include a book on polymer characterization by hyphenated and multidimensional techniques (Provder et al., 1995), a review on polymer analysis by 2DLC (van der Horst and Schoenmakers, 2003), and two reviews on two-dimensional techniques in peptide and protein separations (Issaq et al., 2005 Stroink et al., 2005). Reviews on multidimensional separations in biomedical and pharmaceutical analysis (Dixon et al. 2006) and multidimensional column selectivity (Jandera, 2006) were recently published. Suggested nomenclature and conventions for comprehensive multidimensional chromatography were published in 2003 (Schoenmakers et al., 2003), and a book chapter in the Advances in Chromatography series on MDLC was published in 2006 (Shalliker and Gray 2006). 

Dixon, S.P., Pitfield, I.D., Perrett, D. (2006). Comprehensive multi-dimensional liquid chromatographic separation in biomedical and pharmaceutical analysis a review. Biomed. Chromatogr. 20, 508-529. 

Table 5.1 lists several heart-cut and comprehensive techniques. Heart-cut 2DLC is very common and has great application for the increased resolution of one or several components from the first dimension (Augenstein and Stickler, 1990 Majors, 1980 Pasch et al., 1992 and Dixon et al., 2006). Heart-cut 2DLC for the analysis of polymers is often referred to as cross-fractionation (Balke and Patel, 1980). Protein digest analysis with MS/MS identification has been called multidimensional protein identification technology or MUDPIT. This is described in detail in Chapter 11. 

Rice, N., P. Dixon, D. Lloyd and D. Roberts (2000), Derivation of a needs based capitation formula for allocating prescribing budgets to health authorities and primary care groups in England regression analysis , British Medical Journal, 320, 284-8. 

Dixon, L. C. W. and L. James. On Stochastic Variable Metric Methods. In Analysis and Optimization of Stochastic Systems. Q. L. R. Jacobs et al. eds. Academic Press, London (1980). 

Dixon, A. M. and Larive, C. K. (1997). Modified pulsed-field gradient NMR experiments for improved selectivity in the measurement of diffusion coefficients in complex mixtures application to the analysis of the Suwannee River fulvic acid, Anal. Chem., 69, 2122-2128. 

Renfrew, C., Dixon, J.E. and Cann, J.R. (1968). Further analysis of Near Eastern obsidians. Proceedings of the Prehistoric Society 34 319-331. 

Schuster had an informed interest in chemical problems. He taught a course in chemical physics that was attended by chemistry honors students. Topics included spectrum analysis, saccharimetry, and electrolysis. In 1894, he organized a fortnightly "physical colloquium" for second- and third-year physics students joined by some chemistry honors students. He closely followed the chemical research of his colleagues, Roscoe and Harold Baily Dixon. In interpreting results in his special field of spectroscopy and in electrochemistry, Schuster visualized an "ionic" mechanism of electrical conduction in liquids and gases.60... 

---