Dings inhibition

The color development of photochromic compounds can also be utili2ed as a diagnostic tool. The temperature dependence of the fa ding of 6-nitroindolinospiropyran served as the basis for a nondestmctive inspection technique for honeycomb aerospace stmctures (43). One surface of the stmcture to be exarnined was covered with a paint containing the photochromic compound and activated to a violet color with ultraviolet light. The other side of the stmcture was then heated. The transfer of heat through the honeycomb stmcture caused bleaching of the temperature-dependent photochromic compound. Defects in the honeycomb where heat transfer was inhibited could be detected as darker areas. 

Ding, Q. and Keller, J. N. (2001). Proteasome inhibition in oxidative stress neurotoxicity Implications for heat shock proteins. J. Neurochem. 77,1010-1017. 

Tantillo C, Ding J, Jacobo-Molina A, Nanni RG, Boyer PL, Hughes SH, et al. Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase implications for mechanisms of drug inhibition and resistance. J Mol Biol 1994 243 369-387. 

Hsiou Y, Ding J, Das K, Clark AD Jr., Hughes SH, Arnold E. Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution implications of conformational changes for polymerization and inhibition mechanisms. Structure 1996 4 853-860. 

Qin, L., Ding, Y., Pahud, D.R., Chang, E., Imperiale, M.J. and Bromberg, J.S. (1997) Promoter attenuation in gene therapy interferon-gamma and tumor necrosis factor-alpha inhibit transgene expression. Hum. Gene Then, 8, 2019-2029. 

Qin, L. H., Ding, Y. Z., Pahud, D. R., Robson, N. D., Shaked, A. and Bromberg, J. S. (1997). Adenovirus-mediated gene transfer of viral interleukin-10 inhibits the immune response to both alloantigen and adenoviral antigen. Hum. Gene Ther. 8, 1365-1374. 

Navas, III M.A.A., Ding, J.L., Ho, B. Inactivation of Factor C by dimethyl sulfoxide inhibits coagulation of the Carcinoscorpius amoebocyte lysate. Biochem Inti 21 (1990) 805-813. 

Ding, J.B., et al. (1994). Farnesyl-L-cysteine analogs can inhibit or initiate superoxide release by human neutrophils. / Rio/ Chem 269 16837-16844. 

Ding, C. K., Chachin, K., Ueda, Y., and Wang, C. Y. (2002). Inhibition of loquat enzymatic browning by sulfhydryl compounds. Food Chem. 76, 213-218. 

Chen RH, Ding WV, McCormick F. Wnt signaling to beta-catenin involves two interactive components. Glycogen synthase kinase-3beta inhibition and activation of protein kinase G. J Biol Chem.. 2000 275 17894-17899. 

Aulabaugh A, Ding W, Ellestad GA et al (2000) Inhibition of respiratory syncytial virus by a new class of chemotherapeutic agents. Drugs Future 25 287-294... 

LOX has been found to be an important marker for cancer progression within the melanoma system, and therefore could be a useful biomarker and therapeutic target for melanoma chemoprevention (Winer et al., 2002). It also has been found that 12(S)-HETE is involved in the proliferation of pancreatic carcinoma cells (Ding et al., 2001) and inhibition of the 12-LOX has been shown to cause apoptosis of these cells (Tong et ah, 2002). 12-LOX and 12(S)-HETE were also found to enhance proliferation and survival of gastric cancer cell lines (Wong et al., 2001). 

Ding, X. Z.. T.sokos, G. C.. and Kiang, J. G. (1998). Over expression of HSP-70 inhibits the phosphorylation of HSFl by activating prolein phosphatase and inhibiting protein kinase C activity. FASEB J. 12(6), 45... 

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