109-73-9 n-Butyl amine

Organic synthesis 9 [OS 9] Acetyl chloride acylation of n-butyl amine... 

Figure 1. Formation of carbonyl groups in 0.1 mm PP films as a function of irradiation time in Xenotest 150 (13). (UVA)2-(2 -hydroxy-3, 5 -di-tert-butylphenyl)-5-chloro-benzotriazole (Ni-Comp) Nickelf2,2 -thiobis-(4-tert-octylphenolate)]-n-butyl-amine (Benzoate) 2,4-di-tert-butylphenyl-3,5-di-tert-buty 1-4-hydroxy-benzoate (HALS) Bis-(2,2,6,6-tetramethyl-piperidinyl-4)sebacate.

Z.Y. Wu, Y.H. Yan, G.L. Shen, and R.Q. Yu, A novel approach of antibody immobilization based on n-butyl amine plasma-polymerized films for immunosensors. Anal. Chim. Acta 412, 29-35 (2000). 

Free-radical additions of trichlorosilane to acetylenes initiated by benzoyl peroxide were stereospecific trans additions, giving only cis adducts. The same workers observed that tri-n -butyl amine also catalyzed addition of trichlorosilane to phenylacetylene but gave a mixture of cis- and trans -l-phenyl-2-trichlorosilylethene, 1,1-phenyltrichlorosilylethene, and 1-phenyl-l,2-bistrichlorosilylethane (54). No stereospecificity was observable with the amine as catalyst. 

To obtain an N-substituted amine reflux 0.1M ketone, 17 g aluminum filings or foil, 50 ml ethanol, 40 ml 30% aqueous n-butylamine (or other amine), and 0.5 g of mercuric chloride for 3 hours. Cool and pour on 500 g crushed ice and 200 ml 10% KOH. Extract 3 times with ether and dry, evaporate in vacuum (or wash combined ether layers 2 times with 10% HCI, basify acid extract with 15% NaOH and extract 3 times with ether and dry, evaporate in vacuum) to get the n-butyl-amine (or other amine). 

Under conditions favoring an SnI mechanism, i.e. in the presence of silver salts, a competition of nucleophiles was observed [11b, 26b]. Thus, the acetoxy derivative 104h was obtained in 85% yield in the reaction of 91e with n-butyl amine in THF in the presence of 1 equiv. of AgOAc (Scheme 33) [11b]. Incorporation of the solvent (ROH, DMF) into the product has also been detected, sometimes as the only reaction mode. 

In our NMR studies 143,147,148,322-324) of amine and other adducts of Ni[R-dtp]2 complexes neat amines were employed in order to eliminate variations in extent of association (H-bonding) of the amines, to permit observation of NH proton shifts, and to maximize the concentration of the preferred adduct. The use of high concentration of primary amines in solutions with Ni[R-dtp]2 complexes can lead to products other than those expected, e.g., with aliphatic diamines, the R-dtp anion salts of f/zs(diamine)nickel(ll) chelates are obtained ). Furlani and co-workers ) have shown that Ni-(ethyl-dtp)2 reacts with n-butyl amine to yield complexes containing the NiS2N4 chromophore, presumably with monodentate ethyl-dtp. In all work with adducts it is necessary to assure that the complexes, adduct molecules and solvent systems are anhydrous. A number of authors 132,284,295,329) shown that Ni[ R-dtp ]2 complexes decompose when in contact with water. 

FAB mass spectrometry of cluster-opened 3 and the isomeric mixture of n-butyl-amine adducts 4 revealed an unprecedented fragmentation behavior [12]. Whereas the usual exohedral adducts of Cjq exhibit typical characteristics, namely relatively... 

Fia. 5. Differential heats of adsorption of n-butyl amine at 26° versus surface coverage 9. (1) Attapulgite clay. (2) Kaolin-based cracking catalyst. 

The bis-diethylacetal of di-(4-oxo-n-butyl)amine (182) was obtained from y-aminobutyraldehyde diethylacetal (180) and y-chlorobutyral-dehyde acetal (181) and, after removal of acetal protecting groups, converted into 1-formylpyrrolizidine (183) without isolation of the intermediates. The final condensation was achieved by Babor et oZ.,109 who isolated 1-formylpyrrolizidine in ca. 10-15% yield at pH 4—4.5. Hydrogenation of the compound over platinum afforded 1-hydroxymethylpyrrolizidine, which they claimed to be ( + )-isoretronecanol. Leonard and Blum123 carried out the same condensation at pH 7 and reduced the resultant aldehyde, without isolation, with sodium boro-... 

On the basis of the polarographic studies, the direct electron transfer polymerizations of the monomers, of which half-wave potentials could be measured, were conducted keeping the potential at a level where the monomer alone was reduced and the electrolyte was not affected. During the electrolysis of a-methyl-styrene, for example, the red color of the carbanion was observed around the cathode, but dissipacted and vanished quickly. Only low polymers were found in the cathodic compartment, but no polymer in the anolyte. In the polymerization of other monomers almost identical results were obtained. From the fact that tri-n-butyl-amine was detected in the catholyte and analysis of the end group of polymers obtained, two possible termination steps were postulated ... 

An even more convincing argument is provided by the studies (46), results of which are also shown in Fig. 14. Tri-n-butyl amine in dimethyl formamide induces only a slow polymerisation of L-proline NCA whereas the polymerisation of y-ethyl-L-glutamate NCA is very fast under these conditions even if the concentration of the base is reduced by a factor of ten (78, 46). This is a striking observation since proline NCA is an extremely reactive monomer and polymerises very fast on addition of a primary amine. However, addition of 3-methyl hydantoin,... 

This reaction represents a general method for the preparation of secondary amines thus, di-n-butyl amine has been obtained from di-w-butyl cyanamide in yields of 75 per cent of the theoretical amount. 

Moreover, the formation of enoxy-silanes via silylation of ketones127 by means of N-methyl-N-TMS-acetamide (1 72) in presence of sodium trimethylsilanolate (173) was reported in 1969 and since then, the use of silylating reagents in presence of a catalyst has found wide appreciation and growing utilization as shown in recent papers128-132 (Scheme 27). Diacetyl (181) can be converted by trifluoromethylsul-fonic acid-TMS-ester (182) into 2,3-bis(trimethylsiloxy)-l, 3-butadiene (7treatment with ethyl TMS acetate (7 5)/tetrakis(n-butyl)amine fluoride l-trimethylsiloxy-2-methyl-styrene (i<56)130. Cyclohexanone reacts with the combination dimethyl-TMS-amine (18 7)/p-toluenesulfonic acid to 1-trimethylsiloxy-l-cyclohexene (iSS)131. Similarly, acetylacetone plus phenyl-triethylsilyl-sulfide (189) afford 2-triethylsiloxy-2-pentene-4-one (790)132. ... 

Into a solution containing a-naphthoic acid chloride in benzene with agitation and cooling for 0.5 h a benzene solution of N,N-diethylamine-ethyl-N -(n-butyl)amine is dropped. As the dropping is ended, the solution is kept under agitation in a water bath for 3 h. 

It appears that both JL, and 3 are produced as intermediates during the decomposition of an Amadori compound. There is little evidence, based on end product isolation that the 4-deoxyosone (2) is produced to any extent in these reactions. An early isolation of 1, by Anet (6), was accomplished by decomposing an Amadori compound ("difructose glycine") in aqueous solution. Subsequent studies have shown that Amadori compounds are easily converted to HMF in dilute acid solution as well. Furthermore, Kato s (8) published preparation of 3-deoxyosone, in which glucose is reacted with N-butyl amine almost certainly involves the intermediate formation of an Amadori compound and its decomposition in situ. Thus, it can be reasonably concluded that 3-deoxyosones are produced from Amadori compounds during their degradation. 

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