Dextromethorphan pseudoephedrine

Ulcyte, Urbal Splenda dextromethorphan pseudoephedrine sufentanil Sufenta nisoldipine sucralfate sulindac sulfacetamide sulfacetamide sulfacetamide sulfacetamide sulfacetamide... 

Bromatane DX—dextrometho qihan HBr, brompheniramine maleate, pseudoephedrine HC1 Cardec DM—dextromethorphan HBr, carbinoxamine maleate, pseudoephedrine HC1... 

Sudafed Noil-Drowsy Severe Cold Formula Maximum Strengtli Tablets—dextromethorphan HBr, pseudoephedrine HC1, acetaminophen Tannic-12 Tablets—carbetapentane tannate, chlorpheniramine tannate... 

Tussafed Syrup—dextromethorphan HBr, carbinoxam-ine maleate, pseudoephedrine HC1 Tussend Tablets—hydrocodone bitartrate, chlorpheniramine, pseudoephedrine HC1 Vanex HD Liquid—hydrocodone bitartrate, chloqihen-iramine, phenylephrine HC1... 

Many commonly used medications also contain substances that are eliminated by the MAOIs and must not be taken by these patients. The list of medications to be avoided inclndes the narcotic pain reliever meperidine (Demerol), and many over-the-connter cold remedies containing dextromethorphan or pseudoephedrine. Finally, patients taking MAOIs must also avoid medications that elevate serotonin levels. This inclndes certain appetite snppressants and antidepressants including the SSRIs, venlafaxine, duloxetine, mirtazapine, nefazodone, and trazodone. Medications that interact with the MAOIs cannot be taken until at least 2 weeks after the MAOI has been stopped. 

A) UV spectrum of an extract elixir containing pseudoephedrine. dextromethorphan and triprolidine. (B) Second derivative spectrum of the extract. Note the absorbance maximum of dextromethorphan disappears. 

Pseudoephedrine hydrochloride 30 mg, triprolidine hydrochloride 1.25 mg, dextromethorphan bromide 10 mg and preservatives. 

X 10 ml of chloroform. The chloroform layers are combined and evaporated to dryness using a rotary evaporator. The residue is dissolved in ca 10 ml of methanol and transferred to a 100 ml volumetric flask and then diluted to volume with mobile phase. The areas of the peaks obtained from the linctus extract are compared with a solution containing pseudoephedrine.HCl, dextromethorphan.HBr and triprolidine.HCl (structures shown in Fig. 11.14) at the same concentrations as would be expected in the linctus extract. 

The HPLC chromatogram of an extract from a linctus containing pseudoephedrine, dextromethorphan, triprolidine and methylparaben. ODS column 25 cm x 4.6 mm, mobile phase acetonitrile/0.05 M phosphate buffer pH 6.8 (35 65) 1 ml/min. UV monitoring at 260 nm. 

Rx with pseudoephedrine, dextromethorphan (Bromadine-DM, Bromarest DX, Bromatane DX, Bromfed DM, Bromphen DX, Dimetane DX, Myphetane DX)... 

After reaching this temperature, dissolve sequentially, dextromethorphan hydrobromide, chlorpheniramine maleate and pseudoephedrine hydrochloride,and saccharin sodium. 

Hanzlick R. 1995. National association of medical examiners pediatric toxicology (pedtox) registry report 3 case submission summary and data for acetaminophen, benzene, carboxyhemoglobin, dextromethorphan, ethanol, phenobarbital, and pseudoephedrine. American Journal of Forensic Medicine and Pathology 16 (4) 270-277. 

A 2-year-old child developed hyperirritability, incoherent babbling, and ataxia after being over-medicated with a pseudoephedrine/dextromethorphan over-the-counter combination cough formulation for upper respiratory symptoms (224). The symptoms abated after withdrawal of the product. 

In another three cases (girls aged 10, 13, and 15 years) severe acute psychosis was associated with the use of an over-the-counter formulation containing ephedrine or pseudoephedrine and dextromethorphan combined with other compounds (225). The psychopathology included agitation, depressed mood, flat affect, pressure of speech, visual and auditory hallucinations, and paranoia. All three improved dramatically, with residual symptoms of irritability, 2-4 days after withdrawal of the mixture and treatment with risperidone 0.5-2.0 mg/day. 

Roberge RJ, Hirani KH, Rowland PL 3rd, Berkeley R, Krenzelok EP. Dextromethorphan- and pseudoephedrine-induced agitated psychosis and ataxia case report. J Emerg Med 1999 17(2) 285-8. 

Soutullo CA, Cottingham EM, Keck PE Jr. Psychosis associated with pseudoephedrine and dextromethorphan. J Am Acad Child Adolesc Psychiatry 1999 38(12) 1471-2. Price LH, Lebel J. Dextromethorphan-induced psychosis. Am J Psychiatry 2000 157(2) 304. 

Oral solution containing at least three of the following—Acetaminophen and salts of Chlorpheniramine, Dextromethorphan, and Pseudoephedrine USP (24, p. 31)... 

Acetaminophen, Dextromethorphan, Hydrobromide, Doxylamine Succinate, and Pseudoephedrine Hydrochloride oral solution USP (24, p. 37)... 

Pseudoephedrine Hydrochloride, Carbinoxamine Maleate, and Dextromethorphan Hydrobromide oral solution USP (24) and NE (19 Eirst Suppl, p. 2654)... 

Tylenol Cold APAP 650 mg Pseudoephedrine hydrochloride 60 mg Dextromethorphan hydrobromide 30 mg... 

In another three cases (girls aged 10, 13, and 15 years) severe acute psychosis was associated with the use of an over-the-counter formulation containing ephedrine or pseudoephedrine and dextromethorphan combined with... 

Combinations of pseudoephedrine with dextromethorphan are often used in over-the-counter formulations. Although they are generally considered safe, two reports... 

A 2-year-old child developed hyperirritability, psychosis, and ataxia after being overmedicated with a cough formulation containing pseudoephedrine and dextromethorphan. The child made an uneventful recovery after an observation period of 4 hours in the emergency department. 

Other ingredients of nonprescription cold and allergy medications include pseudoephedrine, guaifenesin, dextromethorphan, and antihistamines. 

Clinically important, potentially hazardous interactions with amitriptyline, amoxapine, amphetamines, bupropion, citalopram, clomipramine, cyproheptadine, desipramine, dextroamphetamine, dextromethorphan, diethylpropion, dopamine, doxepin, entacapone, ephedra, ephedrine, epinephrine, fluoxetine, fluvoxamine, ginseng, imipramine, levodopa, mazindol, meperidine, methamphetamine, nefazodone, nortriptyline, paroxetine, phendimetrazine, phentermine, phenylephrine, pizotifen, propoxyphene, protriptyline, pseudoephedrine, rizatriptan, sertraline, sibutramine, sumatriptan, sympathomimetics, tramadol, tricyclic antidepressants, trimipramine, tryptophan, venlafaxine, zolmitriptan... 

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