Dexon, poly , absorbable sutures

The first synthetic absorbable suture that reached commercial production is Dexon, manufactured by American Cyanamid Co. It is poly(glycolic acid) prepared by the polymerization of glycolide (14). Another absorbable... 

The first synthetic absorbable suture was made from a homopolymer of glycolic acid by Davis Geek Co. and manufactured with the tradename Dexon (1970). This suture was followed by a second material produced by Ethicon, Inc., in 1974, a copolymer of lactide and glycolide known as poly-glactine 910 or Vicryl. Both Vicryl and Dexon are made from polymer fibers, which are braided to produce sutures. In addition. Vicryl is Teflon coated for... 

Owing to its hydrolytic instability, initially, its use was limited. Currently, polyglycolide and its copolymers poly(lactic-co-glycolic acid) with lactic acid, poly(glycolide-co-caprolactone) with e-caprolactone, and poly(glycolide-co-trimethylene carbonate) with trimethylene carbonate) are widely used to develop synthetic absorbable sutures that were marketed under the trade name of Dexon and are now sold as Surgicryl [61],... 

Scanning electron images of some commercial absorbable sutures (a) Chromic catgut polyglycolic acid family (b) Dexon poly(glycolide/L-lactide) copolymer or polyglactin 910 family ... 

Absorbable suture materials are catgut (collagen derived from sheep intestinal submucosa), reconstituted collagen, polyglycolide (e.g., Dexon , Dexon II , Dexon S ), poly(glycolide/lactide) random copolymer (e.g.. Vicryl ), antimicrobial-coated Vicryl (Vicryl Plus ), poly-/ -dioxanone (e.g., PDS , PDSII PDS Plus), poly(glycolide/trimethylene carbonate) block copolymer (e.g., Maxon ), poly(glycolide/e-caprolactone) (e.g., Monocryl ,... 

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