Dexamphetamine

Therapeutic Function Antiobesity drug Chemical Name d-Amphetamine tannate Common Name Dexamphetamine tannate... 

C22H29FO5 50-02-2) see Dexamethasone lert-butylacetate Dexamethasone 21-isonicotinate Dexamethasone 21 -linolate Dexamethasone phosphate Dexamethasone pivalate dexamphetamine... 

Somoza EC, Winhusen TM, Bridge TP, et al An open-label pilot study of methylpheni-date in the treatment of cocaine-dependent patients with adult attention deficit/ hyperactivity disorder. J Addict Dis 23 77—92, 2004 Sora 1, Wichems C, Takahashi N, et al Cocaine reward models conditioned place preference can be established in dopamine- and in serotonin-transporter knockout mice. Proc Natl Acad Sci U S A 95 7699-7704, 1998 Soral, Hall FS, Andrews AM, etal Molecular mechanisms of cocaine reward combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proc Nad Acad Sci U S A 98 5300-5305, 2001 Spear J, Alderton D Psychosis associated with prescribed dexamphetamine use 0etter). 

Amphetamines (speed sulph, sulphate, uppers, wake-ups, billy whizz, whizz, whites, base) are synthetic stimulants which as medicines have been formed into a variety of tablets. Their current medical use is very limited and in fact only dexamphetamine sulphate, Dexedrine, is now available for use solely in the treatment of narcolepsy. The only other amphetamine available for medical use is methylphenidate (Ritalin) for the treatment of attention deficit syndrome in children. As a street drug, amphetamine usually comes as a white, grey, yellowish or pinky powder. The purity rate of street powders is less than 10%, the rest being made up of milder stimulants such as caffeine, other drugs such as paracetamol or substances like glucose, dried baby milk, flour or talcum powder. 

Hansen, E.L., and McKenzie, G.M. Dexamphetamine increases striatal neuronal firing in freely-moving rats. Neuropharmacology 18 547-552, 1979. 

Warenycia, M.W., and McKenzie, G.M. Immobilization of rats modifies the response of striatal neurons to dexamphetamine. Pharmacol Biochem Behav 21 53-59, 1984a. 

Rollema, J. De Vries, J.B. Westerink, B.H.C. Van Putten, F.M.S. and Horn, A.S. Failure to detect 6-hydroxy dopamine in rat striatum after the dopamine releasing drugs dexamphetamine, methylamphetamine and MPTP. Eur J Pharmacol 132 65-69, 1986. 

Strombom, U.H. and Liedman, B., Role of dopaminergic neurotransmission in locomotor stimulation by dexamphetamine and ethanol, Psychopharmacology, 78, 271, 1982. 

Amphetamine The family name for a group of CNS stimulants, which is also applied specifically to one of them. Amphetamine exists in two forms or isomers, with d-amphetamine (dexamphetamine) being the more potent. 

Dextroamphetamine should be used with caution and only upon medicinal indication in treating narcolepsy, consequences of encephalitis, and other illnesses accompanied by apathy, drowsiness, asthenia, for temporary increase of physical and mental capacity, in treating attention deficit disorder in children, and in treating obesity.Synonyms of this drug are D-amphetamine, dexamphetamine, dexalone, tempodex, zenidex, and many others. 

Amphetamine and related compounds (dexamphetamine, methylphenidate, ephedrine, MDMA [ecstasy], cocaine and other dopaminergic drugs)... 

Stimulants such as dexamphetamine and methylphenidate have also been used to treat depression. They are not widely used. They may have a faster onset of action and have been proposed to initiate treatment, during the time before the other antidepressants become effective. 

Amphetamines (dexamphetamine, meth-amphetamine etc.) are central sympathomi-metics. These are drugs of abuse and repeated use can cause long lasting behavioural abnormalities and can precipitate psychosis. The detail is discussed in chapter Adrenergic drugs. ... 

Dexamphetamine tablets or suspension 20-200 mg/day Not time-limited Monitoring Urine... 

Treatment aimed at short-term cessation of amphetamine use was considered completely unrealistic. After the necessary discussions the substitution prescribing option was initiated, with the harm-reduction objective of at least reducing Peter s injecting and use of street amphetamine. He was given dexamphetamine sulphate liquid 60mg per day, with a plan to reduce gradually over the following months. 

Carnwath T, Gabbay M Barnard f (2000). A share of the action general practitioner involvement in drug misuse treatment in Greater Manchester. Drugs Education, Prevention and Policy, 7, 235-44 Carnwath T, Garvey T Holland M (2002). The prescription of dexamphetamine to patients with schizophrenia and amphetamine dependence. Journal of Psychopharmacology, 16, 372-7... 

Merrill J, McBride A, Pates R, Peters L, Tetlow A, Roberts C, Arnold K, Crean J, Lomax S Deakin B (2005). Dexamphetamine substitution as a treatment of amphetamine dependence a two-centre randomized controlled trial. Drugs Education, Prevention Policy, 12, 94-97... 

Sherman JP (1990). Dexamphetamine for speed addiction. Medical Journal of Australia, 153, 306... 

Hare RH, Dominian J, Sharpe L. Phenelzine and dexamphetamine in depressive illness. BMJ 1962 1 9-12. 

Peck, A.W. et al., A comparison of bupropion hydrochloride with dexamphetamine and amitriptyline in healthy subjects, Br J. Clin. Pharmacol., 7, 469, 1979. 

The composition of amphetamine or dexamphetamine pills or capsules actually is a combination of the various types of amphetamine salts. For instance, the... 

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