Desoximetasone 0.25%

Fluoro-llb,21-dihydroxy-16a-methylpregna-l,4-diene-3,20-dione. See Desoximetasone. 

More recent work in the corticosteroid senes has involved modification of the dihydrox-yacetone side chain at the 17 position Activity is retained, for example, when the hydroxyl group at the 17 position is omitted Thus, addition of the elements of hypobromous acid to tnene 36 [8], gives the bromohydnn 37, treatment with base leads to internal elimination to form the p-epoxide 38, opening of the oxir.ine with hydrogen fluoride gives desoximetasone, 39, [9]... 

Clobetasol Propionate Qobetasone Butyrate Desoximetasone Fluticasone Propionate Halcinonide Mometasone... 

C24H320.-i 1056-37-7) see Desoximetasone 21-acetoxy-3a-hydroxy 16a-methylpregnane-ll,20-dione (C24H36O5 1056-38-8) see Desoximetasone 21-acetoxy-17-hydroxy-16p-methyIpregna l,4,9(ll)-tn-ene-3,20-dione... 

CH5N30 57-56-7) see Azimilide hydrochloride Carbazochrome Cortisone Fluazacoit Trazodone semicarbazide hydrochloride (CHftCIN O 563-41-7) see Desoximetasone Hydrocortisone Nitrofural semicarbazidoacetic acid (C3H7N3O3 138-07-8) see Nitrofurantoin D-serine... 

Darodipine, 107 Dazoxiben, 91 Delapril, 58 Desciclovir, 165 Desipramine, 201 Desoximetasone, 70 Dezaguanine, 162,163 Dezocine, 59 Diazlquone, 51 Difloxacin, 143, 144, 145 Dilevalol, 20 Disoxarll, 86 Diuretic, 130,168 Domperidone, 133 Donetidine, 114 Dopamine, 20 Dopexamine, 22 Doxazosin, 148 Doxorubicin, 62 Dribendazole, 132 Duoperone, 199... 

Examples of group I, i.e. weak or low efficacy topical steroids, are hydrocortisone acetate in various concentrations, methylprednisolone 1.0% and prednisolone 0.5%. Group II, the moderately potent steroids, includes alclometasone dipropionate 0.05%, hydrocortisone butyrate 0.1%, triamcinolone acetonide 0.025% and fluocinolone ace-tonide 0.01%. Group III, the potent steroids, contains among others betamethasone valerate 0.1%, betamethasone dipropionate 0.05%, budesonide 0.025%, desoximetasone 0.05%, fluticasone propionate 0.05%, amcinonide 0.1%, fluocinonide 0.05% and mometasone furoate 0.1%. Group IV comprises the very potent agents such as clobetasol propionate 0.05% and halobetasol propionate 0.05%. 

Amdnonide ointment 0.1% Desoximetasone cream or ointment 0.25%, gel 0.05% Fluodnonide cream, ointment, gel 0.05% Haldnonide cream 0.1%... 

Amdnonide cream 0.1% Desoximetasone cream 0.05% Fluodnolone acetonide cream 0.2% Fluodnonide acetonide ointment 0.025% Ftydrocortisone valerate ointment 0.2%... 

---