Desorption continued atmospheric pressure chemical

DGE a AC AMS APCI API AP-MALDI APPI ASAP BIRD c CAD CE CF CF-FAB Cl CID cw CZE Da DAPCI DART DC DE DESI DIOS DTIMS EC ECD El ELDI EM ESI ETD eV f FAB FAIMS FD FI FT FTICR two-dimensional gel electrophoresis atto, 10 18 alternating current accelerator mass spectrometry atmospheric pressure chemical ionization atmospheric pressure ionization atmospheric pressure matrix-assisted laser desorption/ionization atmospheric pressure photoionization atmospheric-pressure solids analysis probe blackbody infrared radiative dissociation centi, 10-2 collision-activated dissociation capillary electrophoresis continuous flow continuous flow fast atom bombardment chemical ionization collision-induced dissociation continuous wave capillary zone electrophoresis dalton desorption atmospheric pressure chemical ionization direct analysis in real time direct current delayed extraction desorption electrospray ionization desorption/ionization on silicon drift tube ion mobility spectrometry electrochromatography electron capture dissociation electron ionization electrospray-assisted laser desorption/ionization electron multiplier electrospray ionization electron transfer dissociation electron volt femto, 1CT15 fast atom bombardment field asymmetric waveform ion mobility spectrometry field desorption field ionization Fourier transform Fourier transform ion cyclotron resonance... [Pg.11]

Several years later, the next step in the application of MS-MS for mixture analysis was developed by Hunt et al. [3-5] who described a master scheme for the direct analysis of organic compounds in environmental samples using soft chemical ionisation (Cl) to perform product, parent and neutral loss MS-MS experiments for identification [6,7]. The breakthrough in LC-MS was the development of soft ionisation techniques, e.g. desorption ionisation (continuous flow-fast atom bombardment (CF-FAB), secondary ion mass spectrometry (SIMS) or laser desorption (LD)), and nebulisation ionisation techniques such as thermospray ionisation (TSI), and atmospheric pressure ionisation (API) techniques such as atmospheric pressure chemical ionisation (APCI), and electrospray ionisation (ESI). [Pg.152]

An ideal interface should not cause extra-column peak broadening. Historical interfaces include the moving belt and the thermospray. Common interfaces are electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCl). Several special interfaces include the particle beam—a pioneering technique that is still used because it is the only one that can provide electron ionization mass spectra. Others are continuous fiow fast atom bombardment (CF-FAB), atmospheric pressure photon ionization (APPI), and matrix-assisted laser desorption ionization (M ALDl). The two most common interfaces, ESI and APCI, were discovered in the late 1980s and involve an atmospheric pressure ionization (API) step. Both are soft ionization techniques that cause little or no fragmentation hence a fingerprint for qualitative identification is usually not apparent. [Pg.147]

Earlier methods of ionization applied to carotenoids, including electron impact (El), chemical ionization (Cl), a particle beam interface with El or Cl, and continuous-flow fast atom bombardment (CF-FAB), have been comprehensively reviewed elsewhere (van Breemen, 1996, 1997 Pajkovic and van Breemen, 2005). These techniques have generally been replaced by softer ionization techniques like electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI), and more recently atmospheric pressure photoionization (APPI). It should be noted that ESI, APCI, and APPI can be used as ionization methods with a direct infusion of an analyte in solution (i.e. not interfaced with an HPLC system), or as the interface between the HPEC and the MS. In contrast, matrix-assisted laser desorption ionization (MALDI) cannot be used directly with HPEC. [Pg.127]

MS is undoubtedly the solution of the near future for LC detection. Improvements made to interfacing devices together with a continuous and sensible diminution of instrumentation costs promote MS as a universal/selective tunable detection system. Atmospheric pressrue electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) are the most robust and popular devices for interfacing MS to LC systems. In Table 9, LC-MS data for some pesticides are given. Although ESI and APCI are more often used, other LC-MS interfaces produce reliable results in pesticide applications thermospray (TSI), particle beam (PBI) and matrix-assisted postsource decay laser desorption/ionization (CID-PSD-MALDI). [Pg.3605]

Laser desorption atmospheric pressure chemical ionization (LD-APCI) combines a laser system and an APCI source to desorb and ionize small chemical compounds on TLC plates (Figure 7.3) [29]. Vaporization and desorption of analytes from the TLC gel bed was achieved by surface heating with a continuous wave (CW) diode laser operated at 808 nm. It was reported that a laser power density of 10 W/cm enables desorption of analytes from white TLC plates. Furthermore, the application of a graphite suspension (10 mg/mL in isopropanol) on the TLC gel decreased the CW laser power required for analyte desorption to 10" W/cm. Thermally desorbed analytes were postionized by reacting with charged species generated by corona discharge of the air. The TLC LD-APCI/MS approach was first used to characterize... [Pg.111]