Design report—oral

The text on appropriate prescribing and some quotations (designated Report) are based on a UK Parliamentary Report (The National Health Service Drugs Budget 1994 HMSO London). Twelve Members of Parliament took evidence from up to 100 organisations and individuals orally and/or in writing. It is both a surprise and a pleasure to be able to continue to quote with approval from such a source. PNB, MJB. 

I Party Written Design Report and Oral Presentation... 

A sample student design report and the visuals from the oral presentation of the project are given in Chapter 28 of this book. Also included is a critique of these reports. Exanples of the problems described in this chapter are given in the sample report. 

This follows the outline of the results section of a written report described in the document tided Written Design Reports. However, there are a few inportant points to remember. First, a detailed stream flow table will not be easily seen or understood by your audience. Second, what is effectively communicated in a table in a written report might be best communicated orally using a graph or pie chart. Avoid using conplex tables and figures with small print. These can neither be seen in the back of the room nor digested by anyone. 

All of the rules on figures and tables in the document entitled Written Design Reports extend to oral presentations. 

The format and rules for presenting figures, tables (use sparingly if at all in oral presentation), equations, etc., are identical to those in the document Written Design Reports. 

In order to strengthen the constructivist-based approach, the position of student activities and their products (papers, drawings, written reports, oral reports...) in the thirds year Theory of architecture e.g. students were asked to write a scientific autobiography (14), in which they have to theorize the design projects they have designed in the first and second year Design Studio. ... 

Third, previous studies have shown there are elements of engineering education in Vietnam that do not fully match the skills students are expected to demonstrate after graduation. [2, 3, 4] This factor led to the incorporation of a design project. With this facet the students applied theory toward application, in addition to working on teams, preparing a design report, and making a final oral presentation. 

An impressive example of the application of structure-based methods was the design of a inhibitor of the HIV protease by a group of scientists at DuPont Merck [Lam et al. 1994 This enzyme is crucial to the replication of the HIV virus, and inhibitors have bee shown to have therapeutic value as components of anti-AIDS treatment regimes. The star1 ing point for their work was a series of X-ray crystal structures of the enzyme with number of inhibitors boimd. Their objective was to discover potent, novel leads whid were orally available. Many of the previously reported inhibitors of this enzyme possessei substantial peptide character, and so were biologically unstable, poorly absorbed am rapidly metabolised. 

In animals, deaths from acrylonitrile have been reported in several species following inhalation, oral or dermal exposure. In most species, death appears to be related to cyanide poisoning. That the cyanide moiety is involved in human toxicity of acrylonitrile has been reported in a case study in which a human male was sprayed with acrylonitrile when a valve burst (Vogel and Kirkendall 1984). This individual suffered symptoms characteristic of cyanide poisoning, and treatments designed to reduce cyanide levels in the blood were required in order to save his life. 

The critical effect of intermediate-duration exposure to -hexane in humans is neurotoxicity, specifically peripheral neuropathy. No inhalation MRL was derived for this duration because the reports of neurological effects in humans were predominantly case reports with inadequate documentation of exposure levels or comparison with unexposed groups. A large database on neurological effects in rats exists for this duration however, the design of these experiments precluded documentation of clear dose-response relationships within a single study. Because of the limited database for oral exposure to -hexane and the lack of toxicokinetic data for this route, no MRL was derived for oral exposure to -hexane. 

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