Design optimisation

D. A., Beaumont, K., Walker, D. K., Property-based design optimisation of drug absorption and pharmacokinetics, J. Med. Chem. 2001, 44, 1313-1333. 

P. Hashemi and Z. Rahmani, A novel homocystine-agarose adsorbent for separation and preconcentration of nickel in table salt and baking soda using factorial design optimisation of the experimental conditions, Talanta, 68(5), 2006, 1677-1682. 

Property-based design optimisation of drug absorption and pharmacokinetics. 

Property based design optimisation of drug absorption and pharmacokinetics. Journal of Medicinal Chemistry, 44, 1313-1333. 

The alumina-superalloy joints are intended to withstand high service temperatures (700 -1000 C) and thermal cycles typical in power generation processes. The fabrication of a joint should provide a relatively good strength but more important that it will remain relatively stable in the service conditions. Therefore, experimental studies for the joint design optimisation should be carried out and the data for novel procedures and for modelling the FG-structure and FE-analysis should be created. 

Representation from Production and the Technology Transfer group are involved early, e.g., during product and process design/optimisation. 

From competing alternatives select a good base case and improve it by using the techniques of Process Integration. Determine targets for utilities, process water and mass separation agents, as well as for the equipment design. Optimise the final flowsheet. 

Two examples are used to explain where the use of plastics is appropriate in car bodies, and where metals are more appropriate. Comparisons between plastics and wood are difficult, since different processing methods apply, and certain designs are optimum for each material. A design optimised for injection moulding in plastic (Sections 13.5 and 13.6), is neither suitable for anisostropic materials like wood, nor easy to construct. 

Predictions of 2D and 3D woven composite stiffness properties have the adequacy level necessary for their use in practical design optimisations. Meso-level predictors for composite stiffness are integrated with macro-level FE tools for structural analysis. 

Yang, X.S. Firefly algorithm, stochastic test functions and design optimisation. Int. J. Bio-Inspired Comput. 2(2), 78-84 (2010a)... 

Drack L, Zadeh HS (2006) Soft computing in engineering design optimisation. J Int Fuzzy Syst... 

The fuzzy finite element method (FFEM) has become a most valuable tool for the analysis of structural dynamics problems with imprecise parameters. The present paper gives an overview of the status of development of the FFEM. The paper focuses specifically on the capabilities of the method, especially in early stages of design analysis. The formulation of design criteria in the presence of parameter uncertainties is reviewed and options for early design optimisation are discussed. 

Design-related information - including design stage (chemistry route selection, chemistry route detailed evaluation, process design optimisation, process plant design, etc.), chemistry, and equipment. 

We have chosen the reactor volume V as an adjustable design parameter for process modification. The modified design optimisation formula is ... 

The RD D programme of the CAREM project has been advanced to the stage when robustness of the design components is to be demonstrated. Development of computer tools to assist the designer in cost-benefit safety design optimisation could be rated as one of important achievements of the CAREM project. 

F. de Souza Dias, L. S. Alves, W. N. Lopes dos Santos, R. E. Bruns and M. A. Bezerra, Mixture design optimisation of an analytical procedure for iron extraction and determination from cassava leaves by slurry sampling flame atomic absorption spectrometry, Spectrosc. Lett., 2011, 44(6), 388-392. 

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