Defined described

Human pharmacology (Phase I) Assess tolerance Define/describe pharmacokinetics and pharmacodynamics Explore drug metabolism and drug interactions Estimate activity Dose-tolerance studies Single and multiple dose PK and/or PD studies Drug interaction studies... 

Work done in the past is described using past-tense verbs (e.g., analyzed, built, heated, investigated, isolated, measured, performed, synthesized, tested). Knowledge that exists in the present (and presumably into the future) is described using present-tense verbs (e.g., contains, defines, describes, explains, implies, is expected to, provides, suggests). Present tense is also used to describe fixed features of a custom-built instrument (e.g., length and width). Consider the following examples. In each case, the past tense describes actions taken by the researchers that led to their results the present tense describes information that is expected to be true over time. 

This chapter has two aims to demonstrate the necessity of using properly validated and verified methods and to explain what constitutes a validated method, and to provide an introduction to method validation for in-house methods. There is an abundance of published material that defines, describes, and generally assists with method validation, some of which is... 

In this first phase of LCA, the following aspects must be defined/described the purpose and extent of the assessment the descriptive functional unit (represented by a product or service) that is formed and its limits the basis of comparison the components of the product s life cycle and assumptions and possible limitations. 

A function/of the essential variables, is said to be of finite co-dimension if a small perturbation of/gives rise to only a finite number of topological types. It is in this case that a map / of co-rank k can be embedded in a family of deformations (/, x R), parametrized by q variables which form the control space a R. By definition, q, the dimension of the control space, is the co-dimension of the singularity represented by /. The family of functions (/, / X R R) thus defined, describes the universal unfolding of /, in which the function/itself is the member associated with the origin of control space. In our applications the control space is a subset of the nuclear configuration space. 

The methodology for wrapper development is illustrated in Fig. 5.62. It is subdivided into four construction phases (phase 1-4), which are followed by a generation phase (phase 5). In each construction phase specific models are defined, describing both static (phase 1 and. 3) as well as dynamic aspects (phase 2 and 4) of the wrapper. The models are either generated (semi-)automatically (phase 1 and 2) or specified manually (phase 3 and 4). 

The protocol defines how the study will be done (the process, equipment, critical steps, and parameters), and who is responsible for its design, execution, analysis, and approval. The sampling activity is also well defined, describing the locations to be sampled, the sampling devices to be used, the quantities required and time point during processing when they should be taken. The protocol defines all the important process parameters to be studied and analyzed in order to demonstrate each significant step performs reliably in terms of quality and yield. The final approval is reserved for the quality function. 

At the beginning of the planning process, it has to be clarified which questions should be answered by the study. In most cases, the research questions are rather qualitative, unspecific statements than precise algebraic formulations. Hence, such statements have to be operationalized into mathematically manageable terms, l.e. measures have to be defined describing the aspects of the system under study that should be investigated. Such measures are called variables. In the context of experimental studies variables have a lot of attributes depending on their purposes. Table 4.9 shows an overview on the most common attributes of variables. 

However, the periodicity condition (4.518) for paths is to be maintained and properly implemented in approximating the effective-classical partition function (4.525) being, nevertheless, closely and powerfully related with the quantum beloved concept of stationary orbits defined/described by periodic quantum waves/paths. This way, the effective-classical path integral approach appears as the true quantum justification of the quantum atom and of the quantum stabilization of matter in general, providing reliable results without involving observables or operators relaying on special quantum postulates other than the variational principles - with universal (classical or quantum) value. 

Gellin 1990), while chemical leukoderma or toxic vitiligo, although not clearly defined, describes a depigmentation caused by the cutaneous exposure to chemicals that have direct, specific melanocytotoxic effects or suppress the capacity of melanocytes to produce melanin (Cummings and Nordlund 1995). 

For any risk assessment method it is crucial that the problem or risk issue is well defined, described and understood. A common mistake is to start the risk analysis before the process to be analysed is well defined and well delimited. Such an approach is easy to imagine because a problem often creates a sense of urgency that tempts one into action though the framework is not yet understood. This mistake will most likely result in waste of time and persoimel frustration. 

Knowledge define describe identify list name... 

DEFINE, DESCRIBE, AND SPECIFY PERFORMANCE, DESIGN, AND TEST CRITERIA FOR THE SYSTEM ELEMENTS... 

The fundamentals of electronics have evolved to include a wide range of knowledge, empirical data, and a broad range of practice. The focus of this handbook is on the key concepts, models, and equations that enable the engineer to analyze, design, and predict the behavior of complex electrical devices, circuits, instruments, and systems. The reader will find the key concepts of each subject defined, described, and illustrated where appropriate, practical applications are given as well. 

Underline key words, e.g. define , describe , explain , identify and so on. NEBOSH provides definitions of the meanings of these in the examiners reports (see Terminology section later). Using the words in the question when writing the answers will help to keep the answer on track. 

The error signal e is the difference between the output y of the nonlinear system and the output y of the linear system. This signal contains the information how well the nonlinear system N is approximated by the linear model G. In order to quantify this error, a norm on the signal spaces has to be defined, describing the absolute value of a signal. Throughout this presentation we will use the Z/2-norm... 

The strength of a nucleophile is affected by many factors, including polarizability. Polarizability, loosely defined, describes the ability of an atom to distribute its electron density unevenly in response to external influences. Polarizability is directly related to the size of the atom (and more specifically, the number of electrons that are distant from the nucleus). For example, sulfur is veiy large and has many electrons that are distant from the nucleus, and its electron density can be unevenly distributed when it comes near an electrophile. Iodine shares the same feature. As a result, I and HS are particularly strong nucleophiles. This fact will be revisited in the upcoming chapter. 

Remembering Recall previously learned information. Students idenliiy materials in three states of matter, using seientifie terminology (soUd, liquid, gas) and deseribe typical changes of states that oceur when substances are heated or cooled. defines, describes, identifies, knows, labels, lists, matches, names, outlines, reealls, recognises, reproduces, selects, states... 

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