2-Cyclohexen-1 -one

Acetylacetonylbenzoic acid, 58, 55, 56 2-Acetyl-l,3-cyclohexadien-l-ol, 59, 62 Acetylcyclohexane, 55, 25 2-Acetylcyclohexanone, 59, 59 2-ACETYL-2-CYCLOHEXEN-1-ONE, 59,... [Pg.111]

The Pacman catalyst selectively oxidized a broad range of organic substrates including sulfides to the corresponding sulfoxides and olefins to epoxides and ketones. However, cyclohexene gave a typical autoxidation product distribution yielding the allylic oxidation products 2-cyclohexene-l-ol (12%) and 2-cyclohexene-1-one (73%) and the epoxide with 15% yield [115]. [Pg.98]

This material is recrystallized from diethyl ether/pentane (2 1) to give 15.1 g (69%) of 2-iodo-2-cyclohexen-1-one as a pale yellow solid, mp 48.5-49°C (Note 7). If desired, an additional 2.4 g (11% mp 48-49°C) can be isolated by concentration of the mother liquor, column chromatography of the residue on 40 g of silica gel eluting with a mixture of 10% ethyl acetate in petroleum ether, and recrystallization of the collected iodoenone from pentane. [Pg.36]

B. 2-(4-Methoxyphenyl)-2-cyclohexen-1-one. A 500-mL, round-bottomed flask, equipped with a 1.5-in. Teflon-coated magnetic stirring bar and an argon inlet adaptor, is charged with 10.02 g (45.1 mmol) of 2-iodo-2-cyclohexen-1-one, 10.69 g (70.4 mmol, 1.56 eq) of 4-methoxyphenylboronic acid (Note 8), 16.72 g (72.1 mmol, 1.6 eq) of silver(l) oxide (Ag20) (Note 9), 0.85 g (2.8 mmol, 6 mol %) of triphenylarsine (Note 10), 0.53 g (1.4 mmol, 3 mol %) of palladium(ll) bis(benzonitrile)dichloride (Note 11), 200 mL of tetrahydrofuran (THF) and 25 mL of water (Note 12). The reaction mixture, flushed with argon, is stirred for 1 hr and then quenched by the addition of 125 mL of saturated aqueous ammonium chloride. After the solution is stirred for 1 hr, the... [Pg.36]

The Suzuki coupling of 2-iodo-2-cyclohexen-1-one and 4-methoxy-phenylboronic acid is achieved using silver(l) oxide as a suspension in aqueous THF as the base. Unlike earlier reports,15-17 in which up to 6 equiv of Ag2mild conditions, rapid conversion can be achieved at room temperature for a large variety of sensitively functionalized partners in near quantitative yields (see Table).18... [Pg.38]

METHOXYPHENYL)-2-CYCLOHEXEN-1-ONE PREPARATION OF 2-IODO-2-CYCLOHEXEN-1-ONE AND SUZUKI COUPLING WITH 4-METHOXYPHENYLBORONIC ACID (2-Cyclohexen-1-one, 2-(4-methoxyphenyl)- and 2-Cyclohexen-1-one, 2-iodo-)... [Pg.182]

A. 2-lodo-2-cyclohexen-1-one. A 500-mL, three-necked, round-bottomed flask equipped with a 1.5-in. Teflon-coated magnetic stirring bar, glass stopper, 50-mL addition funnel, and a reflux condenser is charged with a 1 1 mixture of 75 mL of anhydrous diethyl ether (Note 1) and 75 mL of pyridine. With vigorous stirring, 53 g (0.21 mol) of iodine (Note 2) is added slowly. At the completion of the addition, the dark brown mixture is stirred an additional 10-20 min until complete dissolution is obtained. [Pg.182]

Cyclohexen-1-one (97%) was purchased from Aldrich Chemical Company, Inc. Caution This chemical is highly toxic glove protection is recommended. [Pg.183]

PREPARATION OF 2-IODO-2-CYCLOHEXEN-1 -ONE AND SUZUKI COUPLING WITH 4-METHOXYPHENYL BORONIC ACID... [Pg.291]

Figure 6.34 Bis-(thio)ureas 111-114 derived from IPDA and results of the screening in the DABCO-promoted MBH reaction between cyclohexanecarbaldehyde and 2-cyclohexen-1-one under neat conditions at 10°C.

Cyanocyclohexene 2-Cyclohexen-1 -one Allyl acetate Stilbene Styrene... [Pg.182]

Rabbits and rats treated orally with isophorone excreted unchanged isophorone in the expired air and in the urine (Dutertre-Catella et al. 1978 Truhaut et al. 1970). The urine also contained 3-carboxy-5, 5-dimethyl-2-cyclohexene-1-one and glucuronic conjugates of... [Pg.57]

Furthermore, analytical methods for the detection of isophorone or its metabolites in humans tissues and fluids were not located. Metabolism studies in rats and rabbits, however, indicated that isophorone, isophorol, dihydroisophorone, 3-carboxy-5,5-dimethyl-2-cyclohexene-1-one, and cis- and... [Pg.63]

Dutertre-Catella CH, Nguyen PL, Dang Quoc Q, Truhaut R. 1978. Metabolic transformations of the 3,5,5-2-cyclohexene-1-one trimethyl (isophorone). Toxicol Eur Res 1(4) 209-216. [Pg.100]

SYNTHESIS OF 3-ETH0XY-6-IETHYL-2-CYCL0HEXEN-1-0NE 2-Cyclohexen-1-one, 3-ethoxy-6-nethy 1-)... [Pg.68]

E-l,2-Dichlorovi nyl)-3-ethoxy-6-methy1-2-cyclohexen-1-one 2-Cyclohexen-l-one, 6-(l,2-dichloroethenyl)-3-ethoxy-6-methyl- (10) (73843-25-1) Diisobutylaluminum hydride Aluminum, hydrodiisohutyl- (8) Aluminum, hydro-bis(2-methylpropyl)- (9) (1191-15-7)... [Pg.79]

See also in sourсe #XX -- [ Pg.431 ]

See also in sourсe #XX -- [ Pg.7 , Pg.44 , Pg.45 , Pg.51 , Pg.66 , Pg.67 , Pg.69 , Pg.95 , Pg.97 , Pg.101 , Pg.107 , Pg.189 , Pg.205 ]

See also in sourсe #XX -- [ Pg.7 , Pg.52 , Pg.55 , Pg.59 , Pg.118 ]

See also in sourсe #XX -- [ Pg.11 , Pg.337 , Pg.338 ]

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