Preparation of 4,4-Dimethyl-2-Cyclohexen-l-One

Purpose To demonstrate the preparation of a cyclohexanone via sequential conjugate addition and an intramolecular aldol condensation. 

Because volatile and flammable solvents are used in this experiment, flameless heating should be used for heating the reaction under reflux and for distilling the product. However, if it is necessary to use a small microburner to distill the product, be sure that no one is using flammable solvents in the laboratory. 

Be certain that all joints in the apparatus are properly lubricated and firmly mated in order to keep vapors from escaping. 

2-Methylpropanal and 3-buten-2-one are highly volatile irritants with penetrating odors. Do nof breathe their vapors. If possible, these chemicals should be handled in a hood and measured using syringes to minimize their release into the laboratory. 

Preparation Sign in at www.cengage.com/login to answer Pre-Lab Exercises, access videos, and read the MSDSs for the chemicals used or produced in this procedure. Review Sections 2.9. 2.11. 2.13. 2.21. 2.22. 2.29. and 6.4. 

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What is the structure of 2-naphthalenesulfonic acid, and what function does it serve in the preparation of 4,4-dimethyl-2-cyclohexen-l-one ... 

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