Cyclizine hydrochloride

Cyclizine Hydrochloride. l-(Diphenylmethyl)-4-methylpipera2ine monohydrochloride [303-25-3] (Mare2ine) (17) is a white crystalline powder, or small colorless crystals, that is odorless or nearly so and has a bitter taste. It melts indistinctly and with decomposition at ca 285°C. One gram of cycli2ine hydrochloride [303-25-3] is soluble in 115 mL water, 115 mL ethanol, and 5 mL chloroform it is insoluble in diethyl ether. It may be made by the synthesis shown in Reference 15. 

Infra-red Spectrum. Principal peaks at wavenumbers 716, 756, 701, 984, 1125, 1496 (cyclizine hydrochloride, KBr disk). (See below)... 

Following a single oral dose of 50 mg of cyclizine hydrochloride to 1 subject, a peak blood concentration of0.069 ig/ml was attained in 2 hours (D. S. Griffin and R. C. Baselt, ibid.). 

Codeine Hydrochloride Dequalinium Acetate Fluorometholone Hexamethonium Bromide Riboflavine Stilbazium Iodide Mianserin Hydrochloride Tacrine Hydrochloride Diclofenac Sodium Vinblastine Sulphate Cyclizine Hydrochloride Amiloride Hydrochloride Protoveratrine B Meclofenamate Sodium 5-Methyltryptamine Hydrochloride Dicoumarol Mebendazole Pipradrol Hydrochloride Carbenoxolone Flucytosine Phanquone Phenytoin... 

Cyclacur, 831 Cycladiene, 537 Cyclaine, 659 Cyclamic acid, xvii Cyclandelate, 496 Cyclazocine, 496 Cyclimorph, 790 Cyclizine, 497, 561 Cyclizine hydrochloride, 497 Cyclizine lactate, 497 Cyclizinium chloride, 497 Cyclobarbital, 498 Cyclobarbitone, 498 Cyclobarbitone calcium, 498 Cyclobec, 535 Cyclobenzaprine, 499 Cyclobenzaprine hydrochloride, 499 Cyclobral, 496... 

Cyclimorph cyclizlne tartrate morphine tartrate, cyclizine [ban, inn) (cyclizIne hydrochloride (usan) cyclizlne tartrate BW 47-83 Valoid ) is one of the piperazine series of histamine H -receptor ANTAGONISTS, and a muscarinic CHOLINOCEPTOR antagonist with SEDATIVE actions. It can be used orally or systemically as an antiemetic in the treatment of nausea, vomiting, vertigo, motion sickness and disorders of the balance function of the inner ear. It is available in preparation together with morphine (e.g. Cyclimorph ). 

A woman who had regularly and uneventfully taken Migral (ergotamine tartrate 2 mg, cyclizine hydrochloride 50 mg, caffeine 100 mg) on a number of previous occasions, took one tablet during a course of treatment with erythromycin 250 mg every 6 hours. Within 2 days she developed severe ischaemic pain in her arms and legs during exercise, with a burning sensation in her feet and hands. When admitted to hospital 10 days later, her extremities were cool and cyanosed. Her pulse could not be detected in the lower limbs. ... 

Migril (Ergotamine tartrate, cyclizine hydrochloride and caffeine hydrate). Wockhardt UK Ltd. Summary of product cha teristics, December 2003. 

Determination of cyclizine hydrochloride in tablets and suppositories 50 mM phosphate (pH 2.3) FSCE [182]... 

Mohammadi A., Kanfer I., Walker R.B., A capillary zone electrophoresis (CZE) method for the determination of cyclizine hydrochloride in tablets and suppositories. J. Pharm. Biomed. Anal, 35, 233-239 (2004). 

Marezine Promethazine (Purepac) Periactin Actidil Tavist Cyclizine hydrochloride Promethazine hydrochloride Cyproheptadine hydrochloride Triprolidine hydrochloride Clemastine fumarate... 

Taking into account the mentioned loss of mass and possible content variation. Table 11.11 presents the required excess of suppositories for increasing batch sizes. This table is based on relatively fast settling substances such as acetylsalicylic acid (180) and cyclizine hydrochloride (180). For instance in paracetamol (45) the content variation... 

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