Syrups promethazine hydrochloride

Each teaspoon (5 mL) of phenergan syrup plain contains 

25 mg promethazine hydrochloride in a flavored syrup base with a pH between 4.7 and 5.2 alcohol, 7%. The inactive ingredients present are artificial and natural flavors, citric acid, D C red no. 33, D C yellow no. 10, FD C blue no. 1, FD C yellow no. 6, glycerin, saccharin sodium, sodium benzoate, sodium citrate, sodium propionate, water, and other ingredients. 

Add item 2 while mixing at slow speed. After addition of item 2, mix for 30 minutes at high speed, temperature 90° to 95 °C. 

Add items 3 and 4 to the manufacturing vessel while mixing and mix until dissolved. 

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Each teaspoon (5 mL) of Phenergan VC with codeine contains 10 mg codeine phosphate (warning — this may be habit forming), 6.25 mg promethazine hydrochloride, and 5 mg phenylephrine hydrochloride in a flavored syrup base with a pH between 4.8 to 5.4 alcohol, 7%. The... 

Strenkoski-Nix LC, Ermer J, DeCleene S, et al. (2000) Pharmacokinetics of promethazine hydrochloride after administration of rectal suppositories and oral syrup to healthy subjects. Am J Health-Syst Pharm 57 1499-1505. 

Prometh with codeine syrup 10 mg codeine phosphate and 6.25 mg promethazine hydrochloride) Promethazine competitively antagonizes histamine at H,-receptor sites and prodnces sedative as well as antiemetic effects. Codeine stimnlates opiate receptors in the CNS in addition to cansing respiratory depression, peripheral vasodilation, inhibition of intestinal peristalsis, stimulation of the chemoreceptors that cause vomiting, increased bladder tone, and suppression of cough. They are indicated in the temporary relief of coughs and upper respiratory tract symptoms associated with allergy or the common cold. 

Prometh VC plain syrup 5 mg phenylephrine hydrochloride and 6.25 promethazine hydrochloride)... 

HYDROCHLORIDE/PHENYLEPHRINE HYDROCHLORIDE/CODEINE PHOSPHATE (Prometh VC w/codeine syrup 6.25 mg promethazine hydrochloride/5 mg phenylephrine hydrochloride/10 mg codeine phosphate/5 mL)... 

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