Creosote bush, Larrea

Downum, K. R., Dole, J. and Rodriguez, E. 1988. Nordihyroguaiaretic acid inter- and intrapop-ulational variation in the Sonoran Desert creosote bush (Larrea tridentata, Zygophyllaceae). Biochem. Syst. Ecol. 16 551-555... 

Plant parts often differ in their levels of secondary metabolites (Table 11.4), some containing extremely high levels. For example, the creosote bush, Larrea tridentata, of the western United States has phenolic resins concentrated in leaves, amounting to as much as 18% of dry weight. In experiments, desert woodrats, Neotoma lepida, selected plant parts of creosote bush with low levels of resins (Meyer and Karazov 1989). 

LT025 Fronczek, F. R., P. Caballero, N. H. Fischer, S. Fernandez, E. Hernandez, and L. M. Hurtado. The molecular structure of 3 -demethoxynorisoguai-acin triacetate from creosote bush (Larrea tridentata). J Nat Prod 1987 50(3) 497-499. 

LT046 Granados, H., and R. Gardenas. Biliary calculi in the golden hamster. XXXVII. The prophylactic action of the creosote bush (Larrea tridentata) in pigmented cholelithiasis produced by vitamin A. Rev Gastroenterol Mex 1994 59(1) 31-35. 

LT048 Moinuddin, S. G., S. Hishiyama, M. H. Cho, L. B. Davin, and N. G. Lewis. Synthesis and chiral HPLC analysis of the dibenzyltetrahydrofuran lignans, larreatricins, 8 -epi-larreatricins, 3,3 -didemethoxyverrucosins and meso-3,3 -didemethoxynectandrin B in the creosote bush (Larrea tridentata) evidence for regiospecific control of coupling. Org Biomol Chem 2003 1(13) 2307-2313. 

Nordihydroguaiaretic acid occurs as the mesoform in the resinous exudate of the creosote bush (Larrea divaricata syn. L. tridentata). Under the generic name masoprocol, it has become available... 

Creosote is the common name applied to variety of products, including coal tar, coal tar pitch, wood creosote, and coal tar creosote. These materials are created by the high temperature treatment of hardwoods or coal, or from the sap of the creosote bush (Larrea tridentata). Some of these compounds are used medicinally, as disinfectants or laxatives, and to treat skin diseases. They are also used as coatings to prevent the decomposition of wood, as insecticides, and fungicides. 

Cho, M.H., Moinuddin, S.G.A., Helms, G.L., Hishiyama, S., Eichinger, D., Davin, L.B. and Lewis, N.G. (2003) (+)—Larreatricin hydroxylase, an enantio-specific polyphenol oxidase from the creosote bush Larrea tridentata). Proc. Natl. Acad. Sci. USA., 100,19641-6. 

J Luo, T Chuang, J Cheung, J Quan, J Tsai, C Sullivan, RF Hector, MJ Reed, K Meszaros, SR King, TJ Carlson, GM Reaven. Masoprocol (nordihydrognaiaretic acid) A new antihyperglycemic agent isolated from the creosote bush(Larrea tridentata). Eur J Pharmacol 346 71-79, 1998. 

Luo J, Chuang T, Cheung J, Quan J, Tsai J, Sullivan C, et al. Masoprocol (nordihydroguaiaretic acid) a new antihyperglycemic agent isolated from the creosote bush (Larrea tridentata). Eur J Pharmacol 1998 346 77-9. 

Creosote is the name used for a variety of products that are mixtures of many chemicals. Wood creosotes are derived from the resin from leaves of the creosote bush (Larrea, referred to herein as creosote bush resin) and beechwood (Feigns, referred to herein as beechwood creosote). Coal tars are by-products of the carbonization of coal to produce coke or natural gas. Coal tar... 

Wood creosotes are derived from beechwood (referred to herein as beechwood creosote) and the resin from leaves of the creosote bush (Larrea, referred to herein as creosote bush resin). Beechwood creosote consists mainly of phenol, cresols, guaiacols, and xylenols. It is a colorless or pale yellowish liquid, and it has a characteristic smoky odor and burnt taste (Miyazato et al. 1981). It had therapeutic applications in the past as a disinfectant, laxative, and a stimulating expectorant, but it is not a major pharmaceutical ingredient today in the United States. Beechwood creosote is obtained from fractional distillation (200-220 °C at atmospheric pressure) of beechwood or related plants. The mixture has only recently been characterized to any significant extent (Ogata and Baba 1989). Phenol,/ -cresol, and guaiacols... 

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