Corynebacterium glutamicum metabolism

Inui M, Suda M, Okino S, Nonaka H, Puskas LG, Vertes AA, Yukawa H (2007) Transcriptional profiling of Corynebacterium glutamicum metabolism during organic acid production under oxygen deprivation conditions. Microbiology 153 2491-2504... [Pg.218]

Kjeldsen, K.R. and Nielsen, J. (2009) In silico genome-scale reconstruction and validation of the Corynebacterium glutamicum metabolic network. Biotechnol Bioeng., 102, 583-597. [Pg.359]

Sahm H, Eggehng L, de Graaf AA. (2000) Pathway analysis and metabolic engineering in Corynebacterium glutamicum. Biol Chem 381 899-910. [Pg.627]

Using this approach, general guidelines for experimental design of C-tracer studies with MS could be shown for the central metabolism of Corynebacterium glutamicum comprising various flux scenarios and tracer substrates [26]. [Pg.48]

Inui, M., Kawaguchi, H., Murakami, S., Vertes, A. A., and Yukawa, H. 2004. Metabolic engineering of Corynebacterium glutamicum for fuel ethanol production under oxygen-deprivation conditions./. Mol. Microbiol. Biotechnol., 8, 243-254. [Pg.261]

WittmannC, Kiefer P, Zelder O (2004) Metabolic fluxes in Corynebacterium glutamicum during lysine production with sucrose as carbon source. Appl Environ Microbiol 70 7277-7287... [Pg.17]

Kiefer P, Heinzle E, Zelder O et al (2004) Comparative metabolic flux analysis of lysine-producing Corynebacterium glutamicum cultured on glucose or fructose. Appl Environ Microbiol 70 229-239... [Pg.17]

Becker J, Klopprogge C, Herold A et al (2007) Metabolic flux engineering of L-lysine production in Corynebacterium glutamicum-over expression and modification of G6P dehydrogenase. J Biotechnol 132 99-109... [Pg.17]

Hiiser AT, Chassagnole C, Lindley ND et al (2005) Rational design of a Corynebacterium glutamicum pantothenate production strain and its characterization by metabolic flux analysis and genome-wide transcriptional profiling. Appl Environ Microbiol 71 3255-3268... [Pg.18]

Analysis and Engineering of Metabolic Pathway Fluxes in Corynebacterium glutamicum 23... [Pg.23]

Table 3 Metabolic engineering of Corynebacterium glutamicum for biotechnological applications. The papers listed comprise either review papers summarizing the progress achieved or recent key contributions.

Lee H-S (2005) Sulfur metabolism and its regulation. In Eggeling L, Bott M (eds) Handbook of Corynebacterium glutamicum. CRC Press, Taylor and Francis, Boca Raton... [Pg.45]

Kromer JO, Wittmann C, Schroder H, Heinzle E (2006) Metabolic pathway analysis for rational design of L-methionine production by Escherichia coli and Corynebacterium glutamicum. Metab Eng 8(4) 353-369... [Pg.46]

Koffas, M.A. Jung, G.Y. Stephanopoulos, G. Engineering metabolism and product formation in Corynebacterium glutamicum by coordinated gene overexpression. Metab. Eng. 2003, 5 (1), 32-41. [Pg.1716]

The mutant which was blocked in the synthesis of branched chain amino acids produced very low levels of methoxy pyrazines. Cultures of this mutant did generate a new N peak and produced a strong butter-like aroma. TVo compounds were identified in these cultures as 2,3,5,6-tetramethy1 pyrazine and diacetyl. The synthesis of tetramethylpyrazine by a Corynebacterium glutamicum that was also metabolically blocked in the branched chain amino acid pathway has previously been reported (24). [Pg.273]

R521 H. Sahm, L. Eggeling and A. A. De Graaf, Pathway Analysis and Metabolic Engineering in Corynebacterium Glutamicum , Biol. Chem., 2000,381, 899... [Pg.36]

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