Corynebacterium glutamicum metabolic fluxes

Using this approach, general guidelines for experimental design of C-tracer studies with MS could be shown for the central metabolism of Corynebacterium glutamicum comprising various flux scenarios and tracer substrates [26]. [Pg.48]

WittmannC, Kiefer P, Zelder O (2004) Metabolic fluxes in Corynebacterium glutamicum during lysine production with sucrose as carbon source. Appl Environ Microbiol 70 7277-7287... [Pg.17]

Kiefer P, Heinzle E, Zelder O et al (2004) Comparative metabolic flux analysis of lysine-producing Corynebacterium glutamicum cultured on glucose or fructose. Appl Environ Microbiol 70 229-239... [Pg.17]

Becker J, Klopprogge C, Herold A et al (2007) Metabolic flux engineering of L-lysine production in Corynebacterium glutamicum-over expression and modification of G6P dehydrogenase. J Biotechnol 132 99-109... [Pg.17]

Hiiser AT, Chassagnole C, Lindley ND et al (2005) Rational design of a Corynebacterium glutamicum pantothenate production strain and its characterization by metabolic flux analysis and genome-wide transcriptional profiling. Appl Environ Microbiol 71 3255-3268... [Pg.18]

Analysis and Engineering of Metabolic Pathway Fluxes in Corynebacterium glutamicum 23... [Pg.23]

Wittmann C, de Graaf A (2005) Metabolic flux analysis in Corynebacterium glutamicum. In Eggeling L, Bott M (eds) Handbook of Corynebacterium glutamicum. CRC Press, Boca Raton... [Pg.45]

Tryfona T, Bustard MT (2005) Fermentative production of lysine by Corynebacterium glutamicum transmembrane transport and metabolic flux analysis. Proc Biochem 40(2) 499-508 Trzecieski 1 (1983) Lactose-reduced ice cream and process for the production thereof. US Patent... [Pg.54]

A., Bindley, N.D. (1996) Growth rate-dependent modulation of carbon flux through central metabolism and the kinetic consequences for glucose-limited chemostat cultures of Corynebacterium glutamicum. Appl. Environ. Microbiol 62(2), 429-436. [Pg.204]

Wendisch, V.F., de Graaf, A.A., Sahm, H, and Eikmanns, B.J. (2000) Quantitative determination of metabolic fluxes during coutilization of two carbon sources comparative analyses with Corynebacterium glutamicum during growth on acetate and/or glucose. [Pg.204]

C. (2013) Increased lysine production by flux coupling of the tricarboxylic acid cycle and the lysine biosynthetic pathway - metabolic engineering of the availability of succinyl-CoA in Corynebacterium glutamicum. Metab. [Pg.207]

Effects of the changes in enzyme activities on metabolic flux redistribution around the 2-oxoglutarate branch in glutamate production by Corynebacterium glutamicum. Bioprocess Biosyst Eng, 25 (5), 291-298. [Pg.207]

Asakura, Y., Kimura, E., Usuda, Y., Kawahara, Y., Matsui, K., Osumi, T., and Nakamatsu, T. (2007) Altered metabolic flux due to deletion of odhA causes L-glutamate overproduction in Corynebacterium glutamicum. Appl. Environ. Microbiol., 73 (4), 1308-1319. [Pg.208]

Vallino, J.J. and Stephanopoulos, G. (1993) Metabolic flux distributions in Corynebacterium glutamicum during growth and lysine overproduction. Biotechnol Bioeng., 41 (6), 633-646. [Pg.216]

Bartek, T., Blombach, B., Lang, S., Eikmanns, B.J., Wiechert, W, Oldiges, M., Noh, K., and Noack, S. (2011) Comparative C metabolic flux analysis of pyruvate dehydrogenase complex-deficient, L-valine-producing Corynebacterium glutamicum. [Pg.216]

Wittmann, C. (2010) Analysis and engineering of metabolic pathway fluxes in Corynebacterium glutamicum for amino acid production. Adv. Biochem. Eng./Biotechnol., 120, 21-49. [Pg.752]

Metabolic Flux Redistribution by the Induction of Glutamic Acid Production in Corynebacterium Glutamicum... [Pg.473]

Shirai T, Fujimura K, Furusawa C, Nagahisa K, Shioya S, Shimizu H. (2007). Study on roles of anaplerotic pathways in glutamate overproduction of Corynebacterium glutamicum by metabolic flux analysis. Microb Cell Eact, 6, 19. [Pg.494]

AsakuraY, Kimura E, UsudaY, Kawahara Y, Matsui K, Osumi T, et al. Altered Metabolic flux due to deletion of odhA causes I glutamate overproduction in Corynebacterium glutamicum. Appl Environ Microbiol 2007 73 1308-19. [Pg.468]

Marx A, de Graaf AA, Wiechert W, EggeUng L, Sahm H. Determination of the fluxes in the central metabolism of Corynebacterium glutamicum by nuclear magnetic resonance spectroscopy combined with metabolite balancing. Biotechnol Bioeng 1996 49 111-29. [Pg.469]

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