Control sexual differentiation

Trisporic acids (Fig. 1) are compounds with a profound physiological action. They are produced by, and act solely on, fungi of the order Mucorales where they control sexual differentiation. The majority of species are heterothallic, where conjugation occurs between two different but compatible... 

Burtis, K. C., and B. X. Baker, Drosophila double sex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides. Cell 56 997-1010, 1989. 

After the fetal gonads are converted into testes by SRY, testosterone and Miillerian-inhibiting substance (MIS) control subsequent sexual differentiation. MIS causes the regression of the Mullerian duct, which would otherwise develop into female genital tracts. Testosterone promotes the development of the Wolffian duct into male internal genitalia, including epididymis, vas deferens, and seminal vesicles. 

McKeown, M., J. M. Belote and B. S. Baker. (1987) "A molecular analysis of transformer, a gene in Drosophila melanogaster that controls female sexual differentiation." Cell 48 489-499. 

A Cascade of Regulated RNA Splicing Controls Drosophila Sexual Differentiation... 

Kallman, K. D., and Schreibman, M. P., 1973, A sex-linked gene controlling gonadotrope differentiation and its significance in determining the age of sexual maturation and size of the platyfish, Xiphophorus maculatus, Gen. Comp. Endocrinol., 21 287. 

TRISPORIC ACID AND THE CONTROL OP SEXUAL DIFFERENTIATION IN THE MUCCXIALES... 

Goldstein, J. L., and Wilson, J. D., 1975, Genetic and hormonal control of male sexual differentiation, J. Cell. Physiol. 85 365. 

Cells from tissues associated with primary and secondary sexual characteristics are under particular endocrine control. Sex hormones determinethe growth, differentiation, and proliferation of such cells. When a tumor develops in such tissues, it is sometimes hormone dependent and the use of anti hormones removes the impetus for the tumor s headlong growth. Many nonsteroidal compounds have estrogenic activity diethylstilbest-jrol (81) may be taken as an example. Certain more bulky an-... 

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