Contact with Skin or Eyes

Repeated exposure of skin to Hquid tetrachloroethylene may defat the skin causing dermatitis. When frequent or prolonged contact is likely, gloves of Viton, nitrile mbber, or neoprene should be used, discarding them when they begin to deteriorate. Tetrachloroethylene can cause significant discomfort if splashed in the eyes. Although no serious injury results, it can cause transient, reversible corneal injury. If contact with skin or eyes occurs, foUow standard first-aid practices. 

The major disadvantage with bromination is the extreme toxicity of bromine. Use a fume hood for all operations. Avoid the breathing of fumes or contact with skin or eyes. Protective clothing and gloves are recommended. 

Chemical Substance A substance usually associated with some description of its toxicity or exposure hazard, including solids, liquids, mists, vapors, fumes, gases, and particulate aerosols. Exposure, via inhalation, ingestion, or contacts with skin or eyes, may cause toxic effects, usually in a dose-dependent manner. 

Routes of administration Inhalation, direct contact with skin or eyes Oral and/or parenteral most likely... 

Dry compound or aqueous solution is corrosive. Contact with skin or eyes can cause irritation. 

Contact with skin or eyes causes irritation. Avoid contact with skin and eyes.3 TLV-TWA 5 mg/m3.13... 

Irritates the skin, eyes and respiratory system. Swallowing would result in internal irritation. Avoid breathing dust. Prevent contact with skin or eyes.1... 

Peroxides, which are used as curing agents for methacrylates, are oxidative in nature. These should not be subjected to high temperatures, fire or acids. Certain biocides used in acrylic formulations are toxic in nature. Such products should not be allowed to make contact with skin or eyes. In the event of such contact, thorough washing should be made with clean water. 

Acute exposure to butyric acid would be anticipated to induce irritation or burns following contact with skin or eyes, or if inhaled. Such effects will occur in a concentration-dependent manner. 

Caution Direct liquid contact with skin or eyes may produce severe burns. Vapors are highly irritating to eyes, nose, throat. May cause injury to lungs, liver, kidneys Patty s Industrial Hygiene and Toxicology. voL 2A, G. D. Clayton, F. E. Clayton, Eds. (Wiley-Interscience, New York, 3rd ed., 1981) pp 2798-2800. This substance may reasonably be anticipated to be a carcinogen Fourth Annual Report on Carcinogens (NTP 85-002, 1985) p 115. 

PERSONAL PROTECTION wear a face shield of at least 8 in. size wear appropriate NIOSH/MSHA-approved respirator, gloves, safety goggles and other protective clothing avoid prolonged or repeated exposure do not allow contact with skin or eyes. 

SPILL CLEAN-UP use water spray to cool and disperse vapors dilute spills to form nonflammable mixtures absorb as much as possible with noncombustible materials such as dry earth, sand or vermiculite remove all sources of ignition do not allow contact with skin or eyes. 

EXPOSURE ROUTES primarily occupational exposure inhalation of fine powders direct contact with skin or eyes ingestion adsorption through skin drinking contaminated water inhalation of dust or mist of azo dyes... 

This substance is moderately toxic by oral route. The oral LD50 values published in the literature vary. The LD50 (oral) in rat is with in the range of 700 mg/kg, comparable to that of Silvex. The toxic symptoms are similar to those of other chlorophenoxy acids. Contact with skin or eye can cause irritation. The vapor is irritant to mucous membranes and upper respiratory tract. 

Acute Human Toxicant Chemical that causes harm to humans after short-term exposures. Harm can occur when chemical is inhaled, swallowed, or comes in contact with skin or eye. 

Toxicology Prevent contact with skin or eyes Precaution Moisture sensitive Storage Store tightly closed < 100 F GP-506 Silicone Fluid [Genesee Polymers]... 

Toxicology LD50 (oral, rat) > 3 g/kg, (dermal, rabbit) > 10 g/kg contact with skin or eyes may cause temporary irritation minimal to mild ocular irritation minimal to si. dermal irritation Ertvirortmerttal 5.3% biodeg. in 5 days Precaution Incompat. with strong oxidizing materials Hazardous Decomp. Prods. Thermal decomp, may produce CO, Storage Store in well-ventilated area below 120 F Macol 52 [BASF/Perf. Chems.]... 

Properties Wh. milky emulsion, very little odor 80% < 0.3 p particle size misc. with water sp.gr. = 1 vapor pressure 24 mm Hg m.p. < 32 C b.p. 212 F flash pt. (PMCC) > 212 F pH 7.0 60% solids Toxicology Contact with skin or eyes may cause temporary irritation Precaution Incompat. with strong oxidizing materials thermal decomp, on exposure to air in excess of 150 C may produce carbon and silicone oxides and formaldehyde... 

Toxicology Contact with skin or eyes may cause temporary irritation Storage Store in well-ventilated area at 32-120 F... 

Toxicology LD50 (oral, rat) 3.99 g/kg contact with skin or eyes may cause irritation... 

Consideration and attention to the concentrations of chemicals within any worker s environment are mandatory, such as chemicals in respired air, in water (used at work or for drinking), food contamination, contact with skin or eyes either directly or by vapor, and possibly radiation from specific chemicals used. The gamering of meaningful data has been slow, and changes in acceptable levels occur, as new resources and studies are produced and policy formulations are agreed upon. 

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