Compound Reviews

In an effort to assess the reliability and consistency of visual inspection by medicinal chemists, the following process was implemented. The approximately 22 000 compounds that did not pass the NR filters were broken up into 11 lists of approximately 2000 compounds each. Two chemists were assigned to each of the lists, and each chemist reviewed two lists. A list of the acceptable compounds was compiled from the reviews. A detailed analysis of the study is being prepared for publication [18]. 

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Addition nomenclature, 1, 37 Addition reactions heterocyclic compounds reviews, 1, 70 Additives... 

Homofolic acid, 5,11-methenyl-tetrahydro-biological activity, 3, 327 Homofolic acid, tetrahydro-biological activity, 3, 327 Homoisoflavanones occurrence, 3, 722 thermoisomerization, 3, 722 thermolysis, 3, 728 Homolytic reactions heterocyclic compounds reviews, 1, 74 Homophthalic acid isocoumarins synthesis from, 3, 830 synthesis, 3, 830 Homophthalic anhydride isochroman-l-one synthesis from, 3, 860 20a-Homoporphyrin nomenclature, 1, 30 Homopterocarpin isolation, 4, 998 ( )- D- Homotestosterone synthesis, 1, 453 Homer-Emmons reaction chromene synthesis by, 3, 749 Hortiacine isolation, 3, 149 Hortiamine isolation, 3, 149... 

H-I-benzopyrans in, 3, 665 biosynthesis, 3, 877 Mass spectrometry in biosynthesis methodology, 1, 86 heterocyclic compounds reviews, 1, 77... 

Phosphorus heterocyclic compounds, 1, 493-538 five-membered ring systems, 1, 513-523 nomenclature, 1, 496 six-membered ring systems, 1, 497-513 Photoaromatization oxirenes from, 7, 125-126 Photobleaching chromenes in, 3, 880 Photochemical reactions heterocyclic compound synthesis from, 5, 159 reviews, 1, 56 heterocyclic compounds reviews, 1, 71, 72... 

Quaternary ammonium compounds biocidal activity mechanism, 1, 401 toxicity, 1, 124 Quaternization heterocyclic compounds reviews, 1, 73 ( )-Quebrach amine synthesis, 1, 490 Queen substance synthesis, 1, 439 4, 777 Quercetin occurrence, 3, 878 pentamethyl ether photolysis, 3, 696 photooxidation, 3, 695 Quercetrin hydrolysis, 3, 878 Quinacetol sulfate as fungicide, 2, 514 Quinacridone, 2,9-dimethyl-, 1, 336 Quinacridone pigments, 1, 335-336 Quinacrine... 

Ring transformations heterocyclic compounds reviews, 1, 70 Ring-chain tautomerism polyheteroatom six-membered rings, 3, 1056 Ripariochromene A synthesis, 3, 751, 755 Robinson-Gabriel synthesis oxazoles, 6, 216... 

Ubichromenol synthesis, 3, 752 Ugi reaction, 5, 830 Uliginosin B, bromo-molecular dimensions, 3, 621 Ullman and Fetvadjian synthesis quinolines, 2, 477 Ullman synthesis acridines, 2, 470-benzacridines, 2, 470 Ultraviolet light absorbers in polymers, 1, 397-398 Ultraviolet spectroscopy heterocyclic compounds reviews, 1, 78... 

Most diazotized heteroaromatic amines undergo normal coupling reactions with common aromatic coupling components, as well as with CH acidic compounds (review Butler, 1975). 

The chemistry of these phthalides has much in common with that of the compounds reviewed in the next chapter, i.e., the feMco-triarylmethanes, and in fact, the parent dyes of the two classes share the same basic chromophoric system. However, the latter are true redox systems, rather than pH indicators, and consequently have a different range of technical applications. The situation is complicated further in that the triarylmethane cationic dyes can also bleach at high pH, giving a hydroxide addition... 

No attempt is made to cover all the complex organic compounds that exist. The classes of organic compounds reviewed are those that occur most frequently in combustion processes and photochemical smog. 

This lead has been pursued extensively at Wyeth-Ayerst, resulting in several additional series of active compounds (reviewed in [340]). Activity was retained by replacement of the quinoline by other benzo-fused heterocycles such as benzothiazole and A -methylbenzimidazole, but the benzoxazoles were inactive no correlation was seen between in vitro and in vivo activities... 

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