Compartmental structure

Wallimann, T., Wyss. M., Brdicza, D., Nicolay, K.. Eppenberger, H.M. (1992). Intracellular compartmentation. structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands The phosphocreatine circuit for cellular energy homeostasis. Biochem. J. 281,21-40. 

Sometimes different competent workers disagree as to the compartmental structure of the same system. 

Therefore, Fick s law, when applied to all elements of the compartmental structure, leads to a system of linear differential equations. There are as many equations as compartments in the configuration. If we set... 

Clearly, once a compartmental structure is postulated, there are many experimental protocols and measurement variables that can be accommodated. One just needs to be sure that the parameters characterizing the compartmental matrix, K, and the parameters characterizing the measurement variables can be estimated from the data generated by the experiment. 

Figure 4 compartmental structure task based crystallizer... 

Smorbukk—a highly compartmentalized structure with a long filling history... 

Chemoattractants and their receptors precisely orchestrate the primary migration of developing lymphocytes into and out of secondary lymphoid organs (SLOs) and the organization of second immune anatomic strucmre within the SLO such as B cell follicles and germinal centers (1-3). Many draining lymph nodes (LN) are located at sites superficially under the skin. They are well-compartmentalized structures with specific microenvironments for lymphocytes. Many lymphocytes reside only temporarily within lymph nodes since they continually recirculate between the blood and the lymph. Most human and mouse lymphocytes enter... 

Eisenfeld, J. (1986). A simple solution to the compartmental structural-identifiability problem. Math. Biosci 79,209-220. 

The first application of the new model approach was to the Ranstad Tailing site in Sweden, a former uranium milling facility. Figures 5.5 and 5.6 illustrate the derivation of a compartmental structure for this site. The tailing layer (T) is situated above a moraine layer (M) and a limestone layer (L). It is surrounded by a collecting ditch that... 

Develop novel capsule architectures, with a compartmentalized structure able to host bioactive compounds with different interfacial properties ... 

The results of experimental and theoretical research on water-soluble (nonstoichio-metric) IPECs based on nonlinear (branched) polyionic species (HPE) complexed with oppositely charged linear PEs (GPE) demonstrated that the main feature of such macromolecular co-assemblies is their pronounced compartmentalized structure, which results from a distinctly nonuniform distribution of the linear GPE chains within the intramolecular volume of the branched HPE. In the case of star-shaped PEs or star-like micelles of ionic amphiphilic block copolymers, this com-partmentalization leads to the formation of water-soluble IPECs with core-corona (complex coacervate core) or core-shell-corona (complex coacervate shell) structures, respectively. Water-soluble IPECs based on cylindrical PE brushes appear to exhibit longitudinally undulating structures (necklace) of complex coacervate pearls decorated by the cylindrical PE corona. 

Compartments. Transitions also include transport of molecules between cell compartments. The set of transitions that a state can be involved in is strictly related to its compartment accordingly, a change in the compartment means a change in the state s information context. The state s compartment is a part of the ontology. As the compartments and their vicinity are cell-type dependent, compartmental structure can be modeled as part of the ontology. Cell membranes create an additional complexity because not only can a molecule be located completely inside the membrane, but it may also communicate with both sides of the membrane as part of the events involved in adjacent compartments. So membranes are considered as separate compartments in the ontology. 

Wallimann T, Wyss M, Brdiczka D, Nicollay K, Eppenberger HM. Significance of intracellular compartmentation, structure and function of creatine kinase isoenzymes for cellular energy homeostasis The Phospho-Creatine Circuit . Biochem J 1992 281 21-24... 

Wallimann, T., M. Bolder, D. Neumann, and U. Schlattner, Compartmentation, structure, and function of creatine kinases a rationale for creatine action, in 6th International Conference on Guanidino Compounds in Biology and Medicine. Cincinatti, OH, 2001 (abstract). 

Wallimann, T., M. Bolder, U. Schlattner, M. Eder, T. Homemann, E. O Gorman, A. Ruck, and D. Brdiczka, Some new aspects of creatine kinase (CK) compartmentation, structure, function and regulation for cellular and mitochondrial bioenergetics and physiology. Biofactors, 8 229-234, 1998. 

Other types of tracer model do not seek to impose a compartmental structure but instead determine a combination of kinetic components which best fit the data. For example the technique of spectral analysis views the tissue response (CjjJ as a convolution between the plasma/blood input (Cp) and a large but finite range of so-called basis functions of the form yexp(-6r) where t is time ... 

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