Collagen hydrogels

Ophthalmologic Intraocular lens Contact lens Corneal bandage Poly(methyl methacrylate) Silicone-acrylate, hydrogel Collagen, hydrogel... 

Figure 9.17 Release of anticancer drugs from poly(HEMAF-collagen hydrogels. Controlled release of 5-fluorouracil 130), mitomycin C (M, 334), and bleomycin Ml 1,417) into phosphate-buffered water at 37 °C from p(HEMA) polymerized in the presence of drug and 5% eoUagen. The hydrogels were hydrated ( 40% water) throughout the experiment. Adapted from [57].

Segura T, Chung P H, Shea L D (2005). DNA delivery from hyaluronic acid-collagen hydrogels via a substrate-mediated approach. Biomat. 26 1575-1584. 

Song K, Qiao M et al (2010) Preparation, fabrication and biocompatibility of novel injectable temperature-sensitive chitosan/glycerophosphate/collagen hydrogels. J Mater Sci Mater Med 21 2835 2... 

Ghezzi CE, Muja N, Marelli B, Nazhat SN. Real time responses of fibroblasts to plastically compressed fibrillar collagen hydrogels. Biomaterials 2011 32 4761-72. 

FIGURE 5.45 (a) Temperature dependence of the TSD current for the initial collagen hydrogel and free ... 

Mao, C. and Kisaalita, W.S. 2004. Characterization of 3-D collagen hydrogels for functional ceU-based biosensing. Biosens. Bioelectron. 19 1075-1088. 

Figure 13.1 The tensile test of collagen hydrogel, nanofibre mesh, and their composite-containing fibroblast cells demonstrating that the mechanical property of hydrogel can be increased significantly by hybridisation with nanofibres and cells, which meets the mechanical compatibility for specific application.

Ahn JI, et al. Crosslinked collagen hydrogels as comeal implants effects of sterically bulky vs. non-bulky carbodiimides as crosslinkers. Acta Biomater 2013 9(8) 7796—805. 

The same copolymer has been used to coat the luminal surface of a tubular scaffold. The scaffold consisted of two collagen layers, extracted from porcine skin, separated by a polypropylene framework, and reinforced with five rings of polypropylene monofilament. This scaffold was implanted in dog [128]. After 14 days, the luminal surface resulted to be completely epithelialized with ciliated columnar and squamous epithelium. Naito et al. [129] developed a tracheal prosthesis using a different approach fibroblast and collagen hydrogels, mechanically supported by osteogenically induced... 

S. Taniguchi, Engineering bioartificial tracheal tissue using hybrid fibroblast-mesenchymal stem cell cultures in collagen hydrogels. Interact. Cardiovasc. Thorac. Surg. 12 (2) (Eebruary 2011) 156-161. 

A. El-Fiqi, J.H. Lee, E.J. Lee, and H.W. Kim, Collagen hydrogels incorporated with sur-face-aminated mesoporous nanobioactive glass Improvement of physicochemical stability and mechanical properties is effective for hard tissue engineering, Acta Biomater., 9 (12), 9508-9521, 2013. 

M. G. Albu, and M. Leca, rheological behaviour of some cross-linked collagen hydrogels for drug delivery use, European Cells and Materials, 10 (1), ISSN 1473-2262, 2005. 

Helary, C., Bataille, I., Abed, A., Illoul, C., Anglo, A., Louedec, L., Letourneur, D., Meddahi-Pelle, A., and Giraud-Guille, M. M. (2010). Concentrated collagen hydrogels as dermal substitutes. Biomaterials 31, 481 90. 

Mao H, Kawazoe N, Chen G (2014) Cellular uptake of single-walled caibon nanotubes in 3D extracellular matrix-mimetic composite collagen hydrogels. J Nanosci Nanotechnol 14 (3) 2487-2492... 

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