Tracheal prosthesis

Okumura N., Nakamura T., Natsume X, Tomihata K., Ikada Y. Shimizu Y. (1994) Experimental study on a new tracheal prosthesis made from collagen-coniugated mesh, tourned of Thoracic (jf Cardiovascular Surgery, 108, 337-45. 

The same copolymer has been used to coat the luminal surface of a tubular scaffold. The scaffold consisted of two collagen layers, extracted from porcine skin, separated by a polypropylene framework, and reinforced with five rings of polypropylene monofilament. This scaffold was implanted in dog [128]. After 14 days, the luminal surface resulted to be completely epithelialized with ciliated columnar and squamous epithelium. Naito et al. [129] developed a tracheal prosthesis using a different approach fibroblast and collagen hydrogels, mechanically supported by osteogenically induced... 

N. Okumura, T. Nakamura, Y. Shimizu, T. Natsume, Y. Ikada, Experimental study of a new tracheal prosthesis made from coUagen-grafted mesh, ASAIO Trans. 37 (3) (1991 Jul-Sep) M317-M319. 

W.E. Neville, J.P. Bolanowski, G.G. Kotia, Clinical experience with the silicone tracheal prosthesis, J. Thorac. Cardiovasc. Surg. 99 (4) (April 1990) 604—612 discussion 612—3. 

Tracheal prosthesis (tracheal stent) of silicone rubber [11] ... 

Siloxane-containing devices have also been used as contact lenses, tracheostomy vents, tracheal stents, antireflux cuffs, extracorporeal dialysis, ureteral stents, tibial cups, synovial fluids, toe joints, testes penile prosthesis, gluteal pads, hip implants, pacemakers, intra-aortic balloon pumps, heart valves, eustachian tubes, wrist joints, ear frames, finger joints, and in the construction of brain membranes. Almost all the siloxane polymers are based on various polydimethylsiloxanes. 

Another development to prevent stent dislocation is the Reynders stent (Reynders Medical Supply, Lennik, Belgium), which is a screw-thread plastic prosthesis. The stent clicks into the tracheal cartilage rings, thus providing better airway-wall adherence. It also has a greater rigidity than sificone stents (Noppen et al. 1996,1999). 

Choi HS, Suh H, Lee JH, Park SN, Shin SH, Kim YH, et al. A polyethylene glycol grafted bi-layered polyurethane scaffold preliminary study of a new candidate prosthesis for repair of a partial tracheal defect. EurArch Otorhinolaryngol 2008 265 809-16. 

Experimental and clinical tracheal repair or anastomosis began in the late 19th century. A few examples of limited tracheal resection and primary anastomosis were cited in the first half of the 20th century [12]. Fmther experimental investigation on potential extent of tracheal resection and primary anastomosis without prosthesis greatly widened these possibilities. Approximately one-half of the adult trachea can be removed and primary reanastomosis performed [99—102], so most tracheal lesions can now be resected and primary anastomosed safely. But resection has several limitations in adult patients, only one-half the tracheal length can be successfully treated and only one-third in pediatric patients [7]. These patients are now treated with palliative techniques such as subpotent laser treatments and stents or T-tubes [14]. 

J. Kim, S.W. Suh, J.Y. Shin, J.H. Kim, Y.S. Choi, H. Kim, Replacement of a tracheal defect with a tissue-engineered prosthesis early results from animal experiments, J. Thorac. Cardiovasc. Surg. 128 (1) (July 2004) 124—129. 

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