From alkali-treated

Sane laboratories (38, 55) reported severe nephrocytanegaly from alkali-treated soy protein while a similar protein, having the same IAL content, does not produce lesions (56). Karayiannis (55) has found that alkali-treated soy protein (supplying 1400-2600 ppm IAL) resulted in nephrocytanegaly whereas 2500 ppm IAL derived from alkali-treated lactalbumin did not induce the lesions. 

Table 3. M- and C-NMR data for the eicosapentaenoic acid derivatives (E-1 and E-2) isolated from alkali-treated EPA prepared by treatment with 70 i 5% humidity at 40 2 C for 6 months according to the methods of ICH stability testing.

The action of alkalis on the disulphide bond is complex and is accompanied by the formation of inorganic sulphides. The bond is severed, but new cross-links arc formed of the type —CHg-S.CHj—, as demonstrated by Horn, Jones, and Ringel J. Biol. Chem., 1941, 138, 141), who isolated lanthionine from alkali-treated wool. 

Figure 8, Distribution of following chromatography of the low-molecular-weight substances from P-labeled gly-copeptide on Bio-Gel P2 (12), The low-molecular-weight substances from alkali-treated peptidophosphogalactomannan that separated from the high-molecular-weight substances on Sephadex G-50 were chromatographed on a column of Bio-Gel P-2, minus 400 mesh (93 X 2.5 cm) with distilled deionized water as the eluent. Fractions (3.4 mL) were analyzed for P and the data are given as cpm per sample.

CAS 9000-70-8 EINECS/ELINCS 232-554-6 Synonyms Gelatine Gelatins White gelatin Definition Complex combination of proteins obtained from partial hydrolysis of collagen derived from animal skin, connective tissues, and bones Type A is derived from acid-treated precursor. Type B from alkali-treated precursor... 

Another difficulty in formulating a simple relationship between LAL and nephrocytomegaly is that proteins of equivalent LAL content produce different biological responses. O Donovan (1976) reported that feeding rats alkali-treated soy protein led to severe nephrocytomegaly, while a different protein with the same LAL content did not produce lesions. Karayiannis (1976) found that alkali-treated soy protein (supplying 1400-2600 ppm LAL) resulted in nephrocytomegaly, whereas 2500 ppm LAL derived from alkali-treated lactalbumin did not. 

The key to the problem seems then to be the measurement of the enzymatic releasability of protein-bound LAL, as mentioned by Slump (1978). Little on this topic can be found in the literature. Using a closed system (pepsin-pancreatin and pepsin-pronase-prolidase-aminopeptidase), Slump (1978) found an LAL release with treated soybean of 3% (1.3 g LAL/16 g N), and of 2% with treated casein (5.5 g LAL/16 g N content) or 0.5% (1.0 g LAL/16 g N content). Using a different vitro digestion system, Finot et al. (1978) reported a 27% release of LAL from alkali-treated lactalbumine. 

Vachon, C., Gauthier, S.F., Jones, J.D., and Savoie, L. (1983) In vitro enzymatic release of amino acids from alkali-treated proteins containing lysinoalanine. Nutr Rep. Intern. 27 119. 

The change of compression strength to percent deformation and the compressibility of the composite samples produced from alkali treated ground bagasse and semichemical pulp, followed the change of both the compression strength and percent deformation (Table 4). 

Definition Complex combination of proteins obtained from partial hydrolysis of collagen derived from animal skin, connective tissues, and bones Type A Is derived from acid-treated precursor. Type B from alkali-treated precursor Properties Faint yel. or amber flake or powd., si. char, boulllon-llke odor In sol n., tasteless sol. In warm water, glycerol, acetic add Insol. In org. soivs., alcohol, chloroform, ether, fixed and volatile oils amphoteric Toxicoiogy LD50 (oral, rat) 5 g/kg may cause anaphylactoid reactions experimental teratogen, reproductive effector TSCA listed Precaution Stable In air when dry, but subject to microbic decomp, when moist or In sol n. 

Table 10. Analysis of fractions isolated from the raw extract obtained from Callophyllis variegata by KCl-fractionation and of the main fraction obtained from alkali-treated (F3T3) by further fractionation with KCl ...

Composite s strength made from alkali treated fibers was superior compared to the composite made from untreated fibers. There was 43% improvement in tensile strength found in sample Aj (229,29 MPa) compared to sample Aj ( 160,81 MPa). Figure 7b shows the rough surface of fibers due to the elimination of the external layer of the fibers during alkali treatment therefore it provides better adhesion between fibers and matrix. Splitting of fibers in multiple area was evidence of this improved interface properties. 

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