Cold cream formulation

The cooling sensation experienced after applying a cosmetic cold cream on one s skin is the result of the evaporation of an alcohol (e.g., ethanol) contained in the cold cream. Formulators of skin products include ethanol to achieve a variety of benefits. For example, alcohol enhances the ability of the components in the cold cream to dissolve. For the consumer, the presence of alcohol eases the application of the cream on the skin, enhances the perfume quality of the mixture, and provides a cooling effect on the skin. 

Note-. This is a typical cold cream formulation. The cooling effect comes from the slow evaporation of water from the applied films. The aromatic is added at as low a temperature as possible to prevent its loss by volatilization during manufacture. 

Jimenez SMM, Fresno CMJ, Selles Flores E. Proposal and pharmacotechnical study of a modern dermo-pharmaceutical formulation for cold cream. Boll Chim Farm 1996 135 364-373. 

Martens-Lobenhoffer et al. (1999) have studied the stability of 8-methoxypsoralen (8-MOP) in various ointments. They found that after 12 weeks storage, the drug was stable in Unguentum Cordes and Cold Cream Naturel however, the Unguentum Cordes emulsion began to crack after 8 weeks. When formulated in a Carbopol gel, 8-MOP was unstable. 

Emerwax . [Henkel/Emery/Cospha] Synthetic waxes wax, emulsifier for cosmetic and pharmaceutical formulations incl. stic, cold creams, makeup, depilatories. 

Jimenez, M.M. Fresco, M.J, Seltas, E, Propo.sal and Phannacoiechmeal Study of a Modem Detmo-pharmaceutical Formulation for Cold Cream. Boll. Chim. Farm.. 135(6) . 364-373. 1996. 

Skin creams are normally made of oil-in-water or water-in-oil emulsions. An emulsion is a colloidal dispersion of one liquid in another (see Chapter 11 for a discussion of colloids). It tries to soften and moisturize the skin at the same time. Cold creams are used in the removal of makeup and as moisturizers, while vanishing creams make the skin appear younger by filling in wrinkles. Typical formulations for cold cream and vanishing cream are... 

Uses Emulsifier and stabilizer for cold processed formulations of w/o creams and... 

For the same reason the addition of an oily phase to water-based products can help considerably in promoting perfume stability. Most perfume materials are far more readily soluble in fats and in oils than in water, and to the extent that the product formulation provides an oil or fat phase into which they can escape, they are sheltered from the attack by the hydroxy ions of bases, the hydrogen ions of acids, the oxidizing agents and enzymes—all of which operate only in the water phase. Hence cloudy cold wave lotions, which contain emulsified oil, are easier to perfume than clear ones, cream depilatories cause less severe problems than fat-free formulations, and so on. 

Despite these difficulties, connections can be made between the microstructure and the physical and sensory properties. We have already discussed some of these, for example, the correlation between ice crystal size and sensory smoothness shown in Figure 7.5. Analysis of physical and sensory data by PCA and other statistical methods is an important tool for example, we saw in Figure 6.18 how changes in formulation and storage conditions (which alter the microstructure) affect the sensory attributes. Another example is the relationship between the ice and air microstructure, the thermal conductivity and the perception of coldness in the mouth. The high thermal conductivity of water ice means that heat is rapidly removed from your mouth when you eat the product. This is one of the reasons why an ice lolly feels colder than an ice cream even if they are actually at the same temperature. Table 7.3 summarizes established links between microstructure, physical and sensory properties. 

Administration usually creates pain, anxiety and phobia, and requires professionally trained staff. Topical anaesthesia (creams, gels, patches or simply cold to numb the area) is usually performed to help to manage the pain and associated fears, as well as to distract the child. There is no taste issue with the parenteral routes but the excipients used must be biodegradable imder the available metabolic processes. This can be a problem in neonates as not all pathways have fully matured. Moreover, formulation composition is critical as some excipients can be toxic. This includes vehicles, preservatives or even the antiseptic used to disinfect the surface of the skin prior to injection (e.g. iodine-containing antiseptic that can be absorbed through the skin). 

Feati es Permits cold formulations and incorporation of high m.w. monoesters into water-based raw material without soivs. or oils Properties Disp. 250 nm partide size disp. in water Use Level 1-5% (shave creams) 1-8% (aq. prod, opadfier) 1-10% (gel detackifier) 2-10% (skin and hair care, mold lubricants) 2-20% (leather, shoe, automotive, furniture prods. textile wood waterproofing) Toxicology No irritation potential Carnauba Wax SP 8 [Strahl Pitsch]... 

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