Colchicum Seeds

Ext. Colchicl Semlnis Fluldum (colchicum seed fluid) Sedative and anodyne. In higher doses. It was emetic and purgative, Used In gout and rheumatism. 

Tincture of Colchicum. Mmst-en 4 troy ounces colchicum seed, in moderately fine powder, with 1 fluid ounce diluted alcohol pack it in a cylindrical percolator, and displace, with diluted alcohol, 2 pints of the tincture. (U. S. Ph.)... 

Eisenmann s Opiated Wine of Colchicum. This consists of a mixture of 0 parts wine of colchicum seed and 1 part wine of opium,... 

Delioux s Wine for Bheuma-tiam, Goutt and Neuralgia. Take 5 parts tincture of colchicum seed, 2 ports tincture of aconite leaves, 1 part tincture of fox-glove, and 200 part.s white Vine. Dose to commence with, i tablc-sponnfnl 3 times a day. 

Bulbs and corns are modified underground stems. They are collected when they are fully grown. Bulbs of Allium cepa and Allium sativa are used. Corm of Colchicum autumnale is the source of the drug. Dried seeds provide source of drugs such as Nux vomica and Ignatia. Lycopodium is produced from spores of the plant Lycopodium clavatum, Opium from the latex of the capsules of the poppy plant, Papaver somniferum and Carbo vegetabilis from the charcoal. Whole plants are also used for the preparation of drugs like Aconitum napellus, Calendula officinalis, Chamomilla, Phytolacca decandra (Cook, 1988). 

An alkaloid obtained from the corm and seeds of the meadow saffron, Colchicum autumnale (Liliaceae) and other Colchicum species. 

Nasreen, A. Gundlach, H. Zenk, M.H. Incorporation of phenethylisoquinolines into colchicine in isolated seeds of Colchicum autumnale. Phytochemistry 1997, 46, 107-115. 

Dehiscence is called porous or apical when the seeds escape through pores at the apex, as in the Poppy valvular, when valye-like orifices form in the wall of the capsule.. Valvular dehiscence is septicidal, when the constituent carpels of a pericarp become disjoined, and then open along their ventral suture. Example Colchicum loculi-cidal, dehiscence into loculij or cells, in wWch each component carpel splits down its dorsal suture, and the dissepiments remain intact. Example Cardamon septifragal dehiscence, a breaking away of the valves from the septa or partitions. Example Orchids (Fig. 98). 

LOIC C Colchicum and demecolchicine Colchicine is an alkaloid, previously extracted from the seeds of the Autumn Crocus or Meadow-saffron, Colchicum autumnale L., but nowadays from the seeds of Gloriosa,... 

AUTUMN CROCUS (or Meadow-Saffron) Colchicum cmtumnak, L., family Colchicaceae, is cultivated as an ornamental plant in gardens. The whole plant, mainly the seed, contains the alkaloid colchicine. 

Major alkaloid extracted from seeds of Colchicum autumnale common meadow saffron. Nausea, vomiting, convulsions, paralysis, death. Used as a treatment for gout and in experimental biology as an arrestor of mitosis to facilitate examination of chromosomes. 

A survey of Yugoslavian Colchicum species revealed the presence of colchicine in C. arenarium, C. autumnale, C. bartolini, C. doerfleri, C. kochii, C. latifolium, C. macedonicum, and C. visianii,178 Unripe seeds of Colchicum plants were found to contain 40 % less colchicine than fully ripe ones. 

Colchlcum The dried root or dried seeds of Colchicum sutmnale, which contain the alkaloid colchicine and possess an emetic, diuretic, and cathartic action. It Is used chiefly for gout and reumatlsm. 

Buchnicek J (1950) Colchicine in ripening seeds of the wild saffron (Colchicum autumnale L). Pharm Acta Helv 25 389 01... 

Colchicum cornigerum Tackh et Drar UAR Corms, seeds... 

Colchicine, CgjHggOgN, was obtained from the seeds and conns of the autumn crocus, Colchicum autumncde L. (Liliacese), by Pelletier and Caventou, and has since been found in other Colchicum spp. and in numerous Liliaceous spp. In Gloriosa superba it occurs with two other alkaloids (a) or CggHggOgNg, leaflets, m.p. 177-8°, and... 

Both the corm and the seed of colchicum (C. autumnale Linn.) contain the alkaloid colchicine (0 4 per cent and 0 3 to 0 6 per cent respectively) and are assayed similarly, so they can be considered together. Only the corm is official in the B.P. 

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