Closure device

When dealing with an entire fire detection system that utilizes more than one type of detector, a Detonator Module greatly expands the flexibility and capability of the system. An individual Detonator Module can accept multiple inputs from UV and IR controllers, other Detonator Modules, manual alarm stations, heat sensors, smoke detectors or any contact closure device. In the event of a fire, any of these devices will cause the internal fire circuitry of the module to activate the detonator circuit, sound alarms, and identify the zone that detected the fire. When properly used, a Detonator Module will add only one millisecond to the total system response time. See Figure 8 for an illustration of a fire detection system with a Detonator Module. 

Pericardial ablation procedure Left auricular closure device... 

Krumsdorf U, Ostermayer S, Billinger K, et al. Incidence and clinical course of thrombus formation on atrial septal defect and patient foramen ovale closure devices in 1,000 consecutive patients. J Am Coll Cardiol 2004 43(2) 302-309. Review. 

A spongy dry cake should be obtained. Flood the chamber with nitrogen gas, and close the container(s) with rubber stoppers via the remote closure device (if available). Crimp the vials with aluminium caps. Store the vial(s) in the fridge at 2-8°C until used. 

Improve fencing around the facility. Check the adequacy of locks and other protective equipment. Consider equipping access gates with timed closure devices. Conduct frequent inspections. 

A second study [43] was a prospective, although not randomized study, evaluating only patients undergoing UAE. This study had 342 patients enrolled, 328 of them received a suture-mediated closure device. There were no major complications. Approximately 21% of the patients complained of anteromedial thigh pain that responded to nonsteroidal anti-inflammatory medications. This pain was postulated to result from irritation of the anterior femoral cutaneous nerve and presumably results from the nerve fibers being trapped by the sutures during deployment. 

If closure devices are going to be used, then complications can be minimized by adherence to meticulous sterile technique and confirmation of the appropriate indication and anatomy. Whether the potential risk of the closure device is outweighed by patient satisfaction and convenience is not clear at this point. 

There has been increased use of percutaneous closure devices for closing the femoral artery puncture site. These devices are particularly helpful in patients that are being anticoagulated. There are a number of types of hemostatic devices hemostatic patches, collagen-mediated devices, and suture... 

Wagner SC, Gonsalves CP, Eschelman DJ, Sullivan KL, Bonn J (2003) Complications of a percutaneous suture-mediated closure device versus manual compression for arteriot-omy closure a case-controlled study. J Vase Interv Radiol 14 735-741... 

Chrisman HB, Liu DM, Bui JT, et al. (2005) The safety and efficacy of a percutaneous closure device in patients undergoing uterine artery embolization. J Vase Interv Radiol 16 347-350 quiz 351... 

During the development of a fetus in utero a natural hole in the heart is created to supply oxygenated blood from the placenta and bypass the nonfunctional lungs. At birth this opening will normally seal and ensure that the septum divides the left from the right atria. However, in about 25% of adults a septal defect still remains and the use of a noninvasive biotextile based closure device is now commonly used to repair this type of defect. The design, function and clinical success of this type of biotextile device is described in Chapter 18. 

Gingras, K., Zaruby, J. and Maul, D. (November 2011). Comparison of V-Loc TM 180 wound closure device and QuiUTM PDO knotless tissue-closure device for intradermal closure in a porcine in vivo model Evaluation of biomechanical wound strength./ouma/ of Biomaterials Research B 1-5. 

Congenital heart disease (CHD) occurs in approximately 25 000 births per year in the United States. An atrial septal defect (ASD) is a spedfic form of CHD and is the third most common type of defect. Many people suffer from this disorder and in many cases it is only detected when the patient reaches middle age. Effective and efficient methods of repair are therefore needed to minimize the risks associated with traditional methods of ASD repair. In recent years, transcatheter closure methods for secundum type ASD have been developed. Currently the Amplatzer Septal Occluder, the Gore Helex Septal Occluder and the NMT Medical CardioSEAL-STARFiex Septal Occlusion systems have received FDA approval for ASD repair, the first of these only in 2001. This indicates that the use of these devices is still in its infancy. It can therefore be assumed that much more can be done to develop improved and more effective closure devices. It is the purpose of this chapter to describe ASDs and to outline the available technology with regard to transcatheter ASD repair devices. Hie discussion will centre around their construction and functioning, with special reference to their textile component. 

Taaffe M, Fischer E, Baranowski A, Majunke N, Heinisch C, Leetz M, Hern R, Bayard Y, Btlscheck F, Reschke M, Hoffmann I, Wunderlich N, Wilson N and Sievert H. Comparison of three patent foramen ovale closure devices in a randomized trial (amplatzer versus CardioSEAL-STARflex versus helex occluder). Am J Cardiol 2008 5/1 101(9) 1353-1358. 

Quill PDQ knotless tissue-closure device, 392 Quill SRS suture, 367... 

V-Loc 180 wound closure device, 392 vacuum-remelted (VM) process, 304 Valiant devices, 653-6 Valsalva aortic root graft, 454 Valsalva sinuses, 486 Vascufll monofilament, 295 vascular endothelial growth factor (VEGF),467... 

The history of biomaterials (i.e. the use of natural or artificial materials in restoring the function of tissue or parts of the body) dates further back than even the most ancient ruins on this beautiful island of Sardinia. The Edgar Smith papyrus papers of over 4000 B.C. describe sutures and other wound closure devices. Later work around 2000 B.C. describe metals in bone repair. Somewhat later, the use of goose quills in vascular repair was mentioned. However, it was not until the 1800 s that we saw the real beginning of metals used in bone reconstruction surgery and in the 1930 s (with the beginning of plastic industries) to see the beginning use of polymers in a variety of reconstruction applications. 

Aker, U.T., Kensey, K.R., Heuser, R.R., Sandza, J.G, and Kussmaul, W.G. 3rd. (1994) Immediate arterial hemostasis after cardiac catherization initial experience with a new puncture closure device. Catheterization and Cardiovascular Diagnosis, 31, 228-232. 

One of the most widely used and successful devices for percutaneous PFO closure is the Amplatzer PFO Occluder (St. Jude Medical Inc., St. Paul, MN), which is a device consisting of two nitinol discs that contain a polypropylene mesh (Meier, 2009). These types of devices have demonstrated complication rates of less than 5% and procedural success in 100% of cases (Taaffe et al., 2008). However, only 65% of the patients showed complete occlusion of the foramen ovale at 30 day follow-up. New generations of PFO closure devices could benefit from tissue scaffold technologies to allow rapid healing and tissue integration to achieve complete occlusion of PFOs at... 

Taaffe, M., Fischer, E., Baranowski, A., Majunke, N., Heinisch, C., Leetz, M., Hein, R., Bayard, Y., Buscheck, F., Reschke, M., Hoffmann, L, Wunderhch, N., Wilson, N., Sievert, H., 2008. Comparison of three patent foramen ovale closure devices in a randomized trial (Amplatzer versus CardioSEAL-STARflex versus Helex occluder). American Journal of Cardiology 101, 1353-1358. 

Gemmete JJ, Dasika N, Forauer AR, Cho K, Williams DM (2003) Successfril angioplasty of a superficial femoral artery stenosis caused by a suture-mediated closure device. Cardiovasc Intervent Radiol 26 410-412... 

Step 7-The catheter and sheath are removed and hemostasis is achieved with manual pressure or the use of a closure device. Peripheral pulses are rechecked and documented to make sure they are stable. Though exceedingly rare, significant changes may signify complications such as access artery dissection or distal thrombosis. 

In patients undergoing splenectomy, distal or proximal splenic arteries can be completely occluded to reduce the risk of intraoperative hemorrhage. After the embolization, if patients have thrombocytopenia, a femoral arterial closure device may help promote hemostasis at the puncture site. Patients commonly experience fever, leukocytosis, and ele-... 

The mechanical properties as well as in-vitro testing of cylindrical dumbbells were also studied (Tables 4-6 and 8-14). As can be seen from the tables, the yield strength and modulus of the aromatic poly(anhydride)s developed by the methods described herein are similar to or greater than poly(p-dioxanone), an absorbable polyester used extensively for medical devices, and poly(anhydride)s described by other researchers. This is another indication that the aromatic poly(anhydride)s have the high molecular weights (I.V. > 1.0 dl/g), and consequently, the high strengths required in wound closure devices. 

B. Breitscheidel, G. Olbert, K. Rossato, and U. Storzum, Single piece closure device made of pvc, US Patent 7 337 913, assigned to BASF Aktiengesellschaft (Ludwigshafen, DE), March 4,2008. 

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